Results 171 to 180 of about 5,247 (206)

Structures and Functions of Mammalian Collectins

2001
Protein-carbohydrate interactions serve multiple functions in the immune system. Many animal lectins (sugar binding proteins) mediate both pathogen recognition and cell-pathogen interactions using structurally related calcium-dependent carbohydrate recognition domains (C-type CRDs).
U, Kishore, K B, Reid
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Collectins and pulmonary innate immunity

Immunological Reviews, 2000
Summary: The surfactant‐associated proteins SP‐A and SP‐D are members of a family of host defense lectins, designated collectins. There is increasing evidence that these pulmonary, epithelial‐derived proteins are important components of the innate immune response to microbial challenge and participate in other aspects of immune and inflammatory ...
E, Crouch, K, Hartshorn, I, Ofek
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A collectin-like protein from tunicates

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2000
Collectins are a sub-family of C-type lectins from mammals and birds that are characterized by their collagen-like domains. The mammalian collectin, mannose binding lectin, has attracted considerable interest because it can activate complement components via a lectin-mediated complement pathway that is independent of immunoglobulins.
S V, Nair, S, Pearce, P L, Green, D, Mahajan, R A, Newton, D A, Raftos   +5 more
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The role of the collectin system in pulmonary defence

Paediatric Respiratory Reviews, 2001
The human collectin system comprises the serum protein, mannose- binding lectin and the hydrophilic surfactant proteins A and D. The three proteins possess structural and functional similarities and are important components of innate immunity. Through a variety of mechanisms, including direct opsonisation and complement activation, they assist in host ...
J, Davies, M, Turner, N, Klein
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Purification, Quantification, and Functional Analysis of Collectins

2020
Native and recombinant collectins are purified by using mannan-agarose and an anti-collectin antibody column. The use of sandwich enzyme-linked immunosorbent assay (ELISA) with two antibodies against human mannan-binding lectin (MBL) enables elucidation of the collectin concentration in the blood, serum, and plasma.
Katsuki, Ohtani, Nobutaka, Wakamiya
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Collectins in urinary tract and kidney diseases

International Urology and Nephrology, 2017
The innate immune system serves as the frontline defense against invading pathogens and initiates an inflammatory response to microorganisms. Collectins are C-type lectins that are structurally characterized by a collagen-like sequence and a carbohydrate recognition domain. Moreover, they are widely expressed throughout the body and are involved in the
Yongfang, Qin, Jingjing, Liu, Jiao, Liu, Fengqi, Hu   +3 more
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Characterization of the Mouse Collectin Gene Locus

American Journal of Respiratory Cell and Molecular Biology, 1999
Abstract Three of the four known mouse collectin genes have been mapped to chromosome 14. To further characterize the spatial relationship of these genes, a bacterial artificial chromosome (BAC) library of mouse chromosome 14 was screened using mouse surfactant protein (SP)-A and -D complementary DNAs (cDNAs).
J, Akiyama, S V, Volik, I, Plajzer-Frick, A, Prince, H, Sago, H U, Weier, J N, Vanderbilt, S, Hawgood, F R, Poulain   +8 more
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The roles of collectins in renal diseases and transplantation

Immunology Letters
The collectins are soluble C-type lectins and a group of proteins characterized with common structural features: a collagen-like domain and a carbohydrate-binding domain. These proteins are essential components of the innate immune system, pivotal for recognizing and eliminating pathogens to protect against infections. Over recent decades, research has
Fu Lv, Wuding Zhou, Ke Li
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Collectins and host defence.

Novartis Foundation symposium, 2007
The collectins are a small family of soluble oligomeric proteins containing collagenous regions and C-type lectin domains. They are related in structure and function to complement protein C1q, and to H-, L- and M-ficolins. In humans, the collectins mannose-binding lectin (MBL) and surfactant proteins A and D (SP-A, SP-D) have important roles in innate ...
Sim, R.B., Clark, H., Hajela, K., Mayilyan, K.R.   +3 more
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Pulmonary Collectins

2022
Paul S. Kingma, Nicholas Guiot, Jeffrey A. Whitsett   +2 more
openaire   +1 more source