Results 161 to 170 of about 5,247 (206)

Collectins and viral infection

Trends in Microbiology, 1995
Members of the collectin protein family are beta-inhibitors of influenza virus infectivity. They bind to carbohydrate on the surface of influenza virus and sterically inhibit virus interaction with host cells, and may also act as opsonins. We propose that collectins, by interacting with glycosylated viruses, act as innate inhibitors of viral infection.
R, Malhotra, R B, Sim
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Expanded collectin family in bullfrog (Rana catesbeiana): Identification and characterization of plasma collectins

Developmental & Comparative Immunology, 2021
BLAST searches against databases for the bullfrog (Rana catesbeiana), using the collectin sequence previously identified in tadpoles, revealed the presence of at least 20 members of the collectin gene family. Phylogenetic analysis demonstrated that the bullfrog possesses expanded gene subfamilies encoding mannose-binding lectin (MBL) and pulmonary ...
Masako, Okada, Takanori, Akimoto, Akinori, Ishihara, Kiyoshi, Yamauchi   +3 more
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Surfactant Collectins and Innate Immunity

Neonatology, 2008
Respiratory pathogens encounter various lines of defenses before infection of the host is established. The innate immune response represents an important first-line protection mechanism against potentially pathogenic microorganisms during early stages of infection of the naive host.
Haagsman, H.P., Hogenkamp, A., van Eijk, M., Veldhuizen, E.J.A.   +3 more
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Collectins and collectin receptors in innate immunity

APMIS, 2000
This thesis is based on nine papers and a review on the collectins and collectin receptors in innate immunity. The collectins are a family of proteins in which the individual chains consist of a C-type lectin domain attached to a collagen domain via an alpha-coiled neck region.
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The Role of Collectins in Host Defense

Seminars in Liver Disease, 1997
Mannose-binding protein (MBP) belongs to a group of Ca(2+)-dependent lectins called collectins that play a role in first-line host defense. It recognizes specific carbohydrate residues (mannose and N-acetylglucosamine) on the surface of microorganisms and promotes the killing of microbes either by acting directly as an opsonin or by activating the ...
M, Sumiya, J A, Summerfield
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Collectins: sentinels of innate immunity

BioEssays, 2007
AbstractCollectins, present in plasma and on mucosal surfaces, are humoral molecules of the innate immune system. They were discovered a hundred years ago in 1906 as the first association of an animal lectin with the immune system. They are a family of calcium‐dependent lectins that recognize pathogen‐associated molecular patterns. They share a similar
Gupta, Garima, Surolia, Avadhesha
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The Pulmonary Collectins and Surfactant Metabolism

Annual Review of Physiology, 2001
▪ Abstract  Lung surfactant covers and stabilizes a large, delicate surface at the interface between the host and the environment. The surfactant system is placed at risk by a number of environmental challenges such as inflammation, infection, or oxidant stress, and perhaps not surprisingly, it demonstrates adaptive changes in metabolism in response to
S, Hawgood, F R, Poulain
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Collectins and Ficolins

Protein-carbohydrate interactions are utilized by the immune system for several defense activities. Collectins and ficolins have a key role in maintaining the balance of surfactants in the lungs and supporting the immune system in the lungs, respectively. This chapter provides an extensive description of two soluble pattern recognition receptors (PRRs),
Hajra, Gupta, Ann Mary, Joseph, Mughair, Abdul Aziz, Faryal, Saeed, Rekha, Kumari, Khaled, Masmoudi, Uday, Kishore, Taruna, Madan   +7 more
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Collectins and Pentraxins

2007
Innate immunity is the first line of defense against pathogens. It plays a key role in the activation and orientation of adaptive immunity. Recognition and elimination of pathogens and of dying cells is mediated by pattern recognition receptors (PPRs) that have both cellular and humoral components.
Uday Kishore, Kenneth B.M. Reid
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Collectins and their role in lung immunity

Journal of Leukocyte Biology, 2003
AbstractThe collectins are a small family of secreted glycoproteins that contain C-type lectin domains and collagenous regions. They have an important function in innate immunity, recognizing and binding to microorganisms via sugar arrays on the microbial surface.
Hickling, T.P, Clark, Howard W., Malhotra, R., Sim, R.B.   +3 more
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