Results 51 to 60 of about 5,247 (206)
Background Surfactant Protein D (SP‐D) is a pattern recognition molecule belonging to the family of collectins expressed in multiple human organ systems, including the lungs.
Benjamin Hoffmann‐Petersen +8 more
doaj +1 more source
3D‐printing of Methacryloylated Recombinant Collagen for Tissue Engineering
Recombinant collagen‐like proteins offer promise as alternatives to mammalian collagens. There is less risk of disease transfer, and changes in structure can be readily introduced. Here, a recombinant collagen‐like protein was methacryloylated for extrusion printing and rapid photo‐crosslinking.
Malachy K. Maher +7 more
wiley +1 more source
The Role of Humoral Innate Immunity in Hepatitis C Virus Infection
Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed.
Richard A. Urbanowicz +2 more
doaj +1 more source
Human SP-D is a potent innate immune molecule whose presence at pulmonary mucosal surfaces allows its role in immune surveillance against pathogens. Higher levels of serum SP-D have been reported in the patients with severe acute respiratory syndrome ...
Miao-Hsi Hsieh +13 more
doaj +1 more source
Arg343 in Human Surfactant Protein D Governs Discrimination between Glucose and N-Acetylglucosamine Ligands [PDF]
Surfactant protein D (SP-D), one of the members of the collectin family of C-type lectins, is an important component of pulmonary innate immunity. SP-D binds carbohydrates in a calcium-dependent manner, but the mechanisms governing its ligand recognition
Allen, Martin +5 more
core +3 more sources
Human surfactant protein D (SP-D) belongs to the family of collectins that is composed of a characteristic amino-terminal collagenous region and a carboxy-terminal C-type lectin domain.
Valarmathy Murugaiah +13 more
doaj +1 more source
S-nitrosylation of surfactant protein-D controls inflammatory function. [PDF]
The pulmonary collectins, surfactant proteins A and D (SP-A and SP-D) have been implicated in the regulation of the innate immune system within the lung. In particular, SP-D appears to have both pro- and anti-inflammatory signaling functions. At present,
Chang-Jiang Guo +8 more
doaj +1 more source
In vivo clearance of surfactant lipids during acute pulmonary inflammation. [PDF]
Background A decrease in pulmonary surfactant has been suggested to contribute to the lung dysfunction associated with pulmonary inflammation. A number of studies have implicated surfactant clearance as a possible mechanism for altered pool sizes.
J Goerke +26 more
core +2 more sources
Proteomic profiling of tissue explant‐ and plasma‐derived extracellular vesicles identified colon adenocarcinoma‐associated and healthy‐associated EV proteins. A 10‐protein EV panel enabled highly sensitive blood‐based detection of colon adenocarcinoma, showed marked postoperative changes, and retained performance in an independent validation cohort ...
Yura Seo +33 more
wiley +1 more source
We present the first high‐quality annotated genome of Pinna rudis and an updated genome assembly for Pinna nobilis, two Mediterranean fan mussel species differentially affected by mass mortality events. Comparative genomic analyses of gene sets associated with the “defensome” show that these genes are largely functionally conserved between the two ...
Stéphane Coupé +6 more
wiley +1 more source

