Advancement in Therapeutic Intervention of Prebiotic-Based Nanoparticles for Colonic Diseases [PDF]
International Journal of Nanomedicine, 2022 Yuehong Ren,1,* Linghui Nie,2,* Chunhua Luo,3,* Shiping Zhu,4 Xingwang Zhang1 1Department of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, People’s Republic of China; 2ASD Medical Rehabilitation Center, the Second People’s ...
Ren Y, Nie L, Luo C, Zhu S, Zhang X
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The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats. [PDF]
, 2013 Corticotropin releasing factor receptor 1 (CRF1) is the key receptor that mediates stress-related body responses. However to date there are no CRF1 antagonists that have shown clinical efficacy in stress-related diseases.
Czimmer, József +7 more
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Nonsteroidal anti-inflammatory drug-induced colopathy: An uncommon cause of positive immunochemical faecal occult blood test in the program for colorectal cancer screening [PDF]
Vojnosanitetski Pregled, 2021 Introduction. Nonsteroidal anti-inflammatory drug-induced colopathy is an uncommon condition associated with the long-term use of enteric-coated and slow-release nonsteroidal anti-inflammatory drugs.
Smolović Brigita +3 more
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Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. [PDF]
, 2020 Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium ...
Farzaneh, Ted +8 more
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Radical surgery for non-neoplastic colonic diseases
Zaporožskij Medicinskij Žurnal, 2023 Aim. To improve the results of surgical treatment for patients with non-neoplastic colonic diseases by optimizing the choice of radical surgery extent. Materials and methods.
V. M. Melnyk
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Hemicolectomía radical laparoscópica: opción de mínima invasión para el cáncer de colon
MedUNAB, 2020 Introducción. El cáncer de colon es una de las principales causas de morbimortalidad a nivel mundial. En Colombia se presentan cerca de 145,600 casos nuevos al año.
Luis Ernesto López Gómez +4 more
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Contrasting Autoimmune Comorbidities in Microscopic Colitis and Inflammatory Bowel Diseases
Life, 2023 Background: Inflammatory bowel diseases (Crohn’s disease and ulcerative colitis) and microscopic colitis (lymphocytic and collagenous colitis) are immune-mediated diseases of the gastrointestinal tract, with distinct pathophysiology. Objective: We sought
Istvan Fedor, Eva Zold, Zsolt Barta
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DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis [PDF]
, 2014 Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Bronsky, Jiri +10 more
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K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]
, 2001 Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian +3 more
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Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]
, 2016 open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio +15 more
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