Results 11 to 20 of about 2,494,908 (263)

Combinatorial Chemistry

open access: yesCHIMIA, 2000
In many areas of chemical synthesis, drug discovery, and materials research, combinatorial approaches are becoming more and more important. One of the most serious bottlenecks in this area is the chemical analysis and screening of the products ...
Renato Zenobi
doaj   +5 more sources

Structurally divergent dynamic combinatorial chemistry on racemic mixtures [PDF]

open access: yesNature Communications, 2020
Structurally divergent reactions on racemic mixtures, which produce distinct chemical species from an enantiomeric mixture, are extremely rare in the literature.
Tiberiu-M. Gianga, G. Dan Pantoș
doaj   +2 more sources

Mesofluidic devices for DNA-programmed combinatorial chemistry. [PDF]

open access: yesPLoS ONE, 2012
Hybrid combinatorial chemistry strategies that use DNA as an information-carrying medium are proving to be powerful tools for molecular discovery. In order to extend these efforts, we present a highly parallel format for DNA-programmed chemical library ...
Rebecca M Weisinger   +3 more
doaj   +2 more sources

Combinatorial chemistry [PDF]

open access: yesDrug Discovery Today, 2002
Morten Meldal, Michael Pirrung
exaly   +6 more sources

The RNA-First Fallacy: Conflating Evolutionary Ancestry with Prebiotic Primacy [PDF]

open access: yesLife
The RNA-World hypothesis remains the most widely accepted framework in origins-of-life research, anchored in compelling biochemical evidence for RNA’s deep evolutionary ancestry.
Amit Kahana
doaj   +2 more sources

Combinatorial chemistry [PDF]

open access: yesNature Biotechnology, 1998
Abstract The field of combinatorial chemistry was instigated primarily in response to the need for large libraries of novel compounds to feed the high throughput screening facilities developed by biologists. Traditional methods of organic synthesis involving the sequential synthesis of individual molecules are simply orders of magnitude ...
J A, Ellman, M A, Gallop
  +9 more sources

The production and characterisation of inorganic combinatorial libraries [PDF]

open access: yes, 2010
With the increasing demand for research into new materials, techniques which are able to produce and characterise a large number of samples rapidly are becoming indispensable.
Karimi, O.
core   +7 more sources

Combinatorial ink-jet printing for ceramic discovery [PDF]

open access: yes, 2006
PhDAn aspirating and dispensing printer established inside a robot gantry equipped with furnace and measurement table is used to prepare thick-film combinatorial libraries.
Wang, Jian
core   +4 more sources

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