Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]
, 2007 Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L., +5 more
core +1 more source
Nonlocal, noncommutative diagrammatics and the linked cluster Theorems [PDF]
, 2011 Recent developments in quantum chemistry, perturbative quantum field theory, statistical physics or stochastic differential equations require the introduction of new families of Feynman-type diagrams. These new families arise in various ways.
Brouder, Christian, Frédéric, Patras
core +3 more sources
An overview of the cycloaddition chemistry of fulvenes and emerging applications
Beilstein Journal of Organic Chemistry, 2019 The unusual electronic properties and unique reactivity of fulvenes have interested researchers for over a century. The propensity to form dipolar structures at relatively low temperatures and to participate as various components in cycloaddition ...
Ellen Swan +2 more
doaj +1 more source
Biomolecules, 2020 The stability and the degradation of polymers in physiological conditions are very important issues in biomedical applications. The copolymer of hyaluronic acid and poly-D,L-lactic acid (made available in a product called DAC®) produces a hydrogel which ...
Tatiana Guzzo +7 more
doaj +1 more source
Similarity-based data mining in files of two-dimensional chemical structures using fingerprint measures of molecular resemblance [PDF]
, 2011 This paper reviews the use of measures of intermolecular similarity for processing databases of chemical structures, which play an important role in the discovery of new drugs by the pharmaceutical industry.
Willett, P.
core +1 more source
Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
Nature Communications, 2020 Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic prenyltransferases and the universality of this cryptic feature is ...
Haibing He +12 more
doaj +1 more source
Library Design in Combinatorial Chemistry by Monte Carlo Methods
, 2000 Strategies for searching the space of variables in combinatorial chemistry experiments are presented, and a random energy model of combinatorial chemistry experiments is introduced.
B. M. Cole +25 more
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Chemoinformatics Research at the University of Sheffield: A History and Citation Analysis [PDF]
, 2003 This paper reviews the work of the Chemoinformatics Research Group in the Department of Information Studies at the University of Sheffield, focusing particularly on the work carried out in the period 1985-2002.
Bishop, N. +3 more
core +1 more source
Química Nova, 2000 Combinatorial chemistry has emerged as a tool to circumvent a major problem of pharmaceutical industries to discover new lead compounds. A rapid and massive evaluation of a myriad of newly synthesised compounds can be carried out. Combinatorial synthesis
Andrei Leitão +2 more
doaj +1 more source
Quantum dot-labelled polymer beads by suspension polymerisation [PDF]
, 2003 CdSe quantum dots with polymerisable ligands have been incorporated into polystyrene beads, via a suspension polymerisation reaction, as a first step towards the optical encoding of solid supports for application in solid phase organic ...
Cummins, Siobhan S. +7 more
core +2 more sources