Results 31 to 40 of about 117,682 (268)

The Rayleigh-Schr\"odinger perturbation series of quasi-degenerate systems [PDF]

open access: yes, 2010
We present the first representation of the general term of the Rayleigh-Schr\"odinger series for quasidegenerate systems. Each term of the series is represented by a tree and there is a straightforward relation between the tree and the analytical ...
Albeverio   +67 more
core   +5 more sources

Aplicações da química combinatória no desenvolvimento de fármacos Applications of combinatorial Chemistry to drug development

open access: yesQuímica Nova, 2001
Combinatorial Chemistry has become a very efficient methodology in drug research. Recent progress in combinatorial synthesis performed both in solid and solution phase have led to a change in the paradigm for the identification and optimization of lead ...
Ricardo L. Araújo Dias   +1 more
doaj   +1 more source

Synthesis of Novel 2-(Pyridin-2-yl) Pyrimidine Derivatives and Study of Their Anti-Fibrosis Activity

open access: yesMolecules, 2020
A pyrimidine moiety exhibiting a wide range of pharmacological activities has been employed in the design of privileged structures in medicinal chemistry. To prepare libraries of novel heterocyclic compounds with potential biological activities, a series
Yi-Fei Gu   +6 more
doaj   +1 more source

Diversity and bioactivity of culturable bacteria from Acanthus ebracteatus

open access: yesGuangxi Zhiwu, 2023
Acanthus ebracteatus is a special kind of rare mangrove plant, possessing great medicinal value. In this paper, in order to study the diversity of endophytic and rhizosphere culturable bacteria in the A.
Zhe LI   +6 more
doaj   +1 more source

Combinatiorial method for surface-confined sensor desing and fabrication [PDF]

open access: yes, 2005
The procedure for the combinatorial fabrication of new sensing materials for cations and anions based on self-assembled monolayers (SAM) is discussed. A library of different sensitive substrates is generated by sequential deposition of fluorophores and ...
Basabe Desmonts, Lourdes   +3 more
core   +3 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition

open access: yeseLife, 2021
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases.
Erich Stefan   +7 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Combinatorial synthesis of oxysulfides in the lanthanum-bismuth-copper system [PDF]

open access: yes, 2020
Establishing synthesis methods for a target material constitutes a grand challenge in materials research, which is compounded with use-inspired specifications on the format of the material.
Gregoire, John M.   +6 more
core  

Programmable biomaterials for dynamic and responsive drug delivery [PDF]

open access: yes, 2016
Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the
Almquist, BD, Kiani, MT, Stejskalova, A
core   +1 more source

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