Results 31 to 40 of about 1,137,818 (369)
Affinity chromatography in dynamic combinatorial libraries: one-pot amplification and isolation of a strongly binding receptor [PDF]
, 2010 We report the one-pot amplification and isolation of a nanomolar receptor in a multibuilding block aqueous dynamic combinatorial library using a polymer-bound template.
Aldaye +63 more
core +2 more sources
Dithioacetal Exchange: A New Reversible Reaction for Dynamic Combinatorial Chemistry.
Chemistry, 2016 Reversibility of dithioacetal bond formation is reported under acidic mild conditions. Its utility for dynamic combinatorial chemistry was explored by combining it with orthogonal disulfide exchange.
Andrea M. Escalante, R. Furlan
semanticscholar +1 more source
3nj Morphogenesis and Semiclassical Disentangling [PDF]
, 2009 Recoupling coefficients (3nj symbols) are unitary transformations between binary coupled eigenstates of N=(n+1) mutually commuting SU(2) angular momentum operators.
Anderson, Roger W. +2 more
core +1 more source
Encoded combinatorial chemistry. [PDF]
Proceedings of the National Academy of Sciences, 1992 The diversity of chemical synthesis and the power of genetics are linked to provide a powerful, versatile method for drug screening. A process of alternating parallel combinatorial synthesis is used to encode individual members of a large library of chemicals with unique nucleotide sequences.
Sydney Brenner, Richard A. Lerner
openaire +3 more sources
Nature Nanotechnology, 2007 This chapter focuses on solid-phase (SP) combinatorial chemistry and libraries, and on their most recent applications in the drug discovery process. The first section provides a short history of combinatorial chemistry, and examines the most relevant trends which appeared recently.
openaire +4 more sources
An overview of the cycloaddition chemistry of fulvenes and emerging applications
Beilstein Journal of Organic Chemistry, 2019 The unusual electronic properties and unique reactivity of fulvenes have interested researchers for over a century. The propensity to form dipolar structures at relatively low temperatures and to participate as various components in cycloaddition ...
Ellen Swan +2 more
doaj +1 more source
Biomolecules, 2020 The stability and the degradation of polymers in physiological conditions are very important issues in biomedical applications. The copolymer of hyaluronic acid and poly-D,L-lactic acid (made available in a product called DAC®) produces a hydrogel which ...
Tatiana Guzzo +7 more
doaj +1 more source
Combinatorial structures to modeling simple games and applications [PDF]
, 2017 We connect three different topics: combinatorial structures, game theory and chemistry. In particular, we establish the bases to represent some simple games, defined as influence games, and molecules, defined from atoms, by using combinatorial structures.
Molinero Albareda, Xavier
core +1 more source
A semantic datagrid for combinatorial chemistry [PDF]
The 6th IEEE/ACM International Workshop on Grid Computing, 2005., 2005 The CombeChem project has designed and deployed an e-science infrastructure using a combination of grid and semantic Web technologies. In this paper we describe the datagrid element of the project, which provides a platform for sophisticated scientific queries and a rich record of experimental data and its provenance.
Taylor, Kieron +5 more
openaire +4 more sources
Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
Nature Communications, 2020 Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic prenyltransferases and the universality of this cryptic feature is ...
Haibing He +12 more
doaj +1 more source