Diversity and bioactivity of culturable bacteria from Acanthus ebracteatus
Acanthus ebracteatus is a special kind of rare mangrove plant, possessing great medicinal value. In this paper, in order to study the diversity of endophytic and rhizosphere culturable bacteria in the A.
Zhe LI+6 more
doaj +1 more source
Similarity-based data mining in files of two-dimensional chemical structures using fingerprint measures of molecular resemblance [PDF]
This paper reviews the use of measures of intermolecular similarity for processing databases of chemical structures, which play an important role in the discovery of new drugs by the pharmaceutical industry.
Willett, P.
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The synthesis of a small library of prospective growth hormone secretagogues [PDF]
Employing tools of combinatorial chemistry, an original methodological approach has been developed and applied for the design and synthesis of a small library of peptide-like compounds, prospective growth hormone (GH) secretagogues.
Pejović Vojislav+2 more
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Towards the Development of Sequence-Selective Artificial Proteases
The development of artificial sequence-selective proteolytic metal complexes is endeavoured by use of encoded combinatorial chemistry.
Helma Wennemers
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Nonlocal, noncommutative diagrammatics and the linked cluster Theorems [PDF]
Recent developments in quantum chemistry, perturbative quantum field theory, statistical physics or stochastic differential equations require the introduction of new families of Feynman-type diagrams. These new families arise in various ways.
Brouder, Christian, Frédéric, Patras
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Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta+3 more
wiley +1 more source
The development of new engineering alloy chemistries is a time consuming and iterative process. A necessary step is characterization of the nano/microstructure to provide a link between the processing and properties of each alloy chemistry considered ...
De Geuser, F.+3 more
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A user-friendly Matlab program and GUI for the pseudorotation analysis of saturated five-membered ring systems based on scalar coupling constants [PDF]
Background: The advent of combinatorial chemistry has revived the interest in five-membered heterocyclic rings as scaffolds in pharmaceutical research. They are also the target of modifications in nucleic acid chemistry.
Hendrickx, Pieter, Martins, José
core +4 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Synthesis of Novel 2-(Pyridin-2-yl) Pyrimidine Derivatives and Study of Their Anti-Fibrosis Activity
A pyrimidine moiety exhibiting a wide range of pharmacological activities has been employed in the design of privileged structures in medicinal chemistry. To prepare libraries of novel heterocyclic compounds with potential biological activities, a series
Yi-Fei Gu+6 more
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