Prognosis of patients with acute exacerbation of combined pulmonary fibrosis and emphysema: a retrospective single-centre study [PDF]
Background Previous analyses of combined pulmonary fibrosis and emphysema (CPFE) cohorts have provided conflicting data on the survival of patients with CPFE.
Yuichi Ikuyama +11 more
doaj +2 more sources
Single-cell RNA sequencing elucidates potential mechanisms of endothelial cells in lung region-specific repair and remodeling in combined pulmonary fibrosis and emphysema [PDF]
Background Combined pulmonary fibrosis and emphysema (CPFE) is a severe and progressive lung disease with limited therapeutic options and poor prognosis. CPFE manifests as emphysema and fibrosis in different lung regions and is frequently associated with
Huiyuan Hu +11 more
doaj +2 more sources
Combined pulmonary fibrosis and emphysema and lung transplantation: current evidence and future directions. [PDF]
Background: Combined pulmonary fibrosis and emphysema (CPFE) patients generally have a poorer prognosis compared to those with either pulmonary fibrosis or chronic obstructive pulmonary disease (COPD)/emphysema alone, as demonstrated by several studies ...
Hage R +3 more
europepmc +2 more sources
Mortality surrogates in combined pulmonary fibrosis and emphysema. [PDF]
Background: idiopathic pulmonary fibrosis (IPF) with co-existent emphysema, termed combined pulmonary fibrosis and emphysema (CPFE) may associate with reduced forced vital capacity (FVC) declines compared to non-CPFE IPF patients.
Zhao A +42 more
europepmc +3 more sources
Effect of combined pulmonary fibrosis and emphysema on patients with connective tissue diseases and systemic sclerosis: a systematic review and meta-analysis [PDF]
Background This study aimed to analyze the literature systematically to determine the clinical characteristics and prognosis of patients with connective tissue disease (CTD) with combined pulmonary fibrosis and emphysema (CPFE) compared to those of ...
Bon San Koo +6 more
doaj +2 more sources
Combined Pulmonary Fibrosis and Emphysema (CPFE): A “New” Smoking-Related Interstitial Lung Disease (ILD) [PDF]
Background: Combined Pulmonary Fibrosis and Emphysema (CPFE) is a distinct syndrome characterized by upper-lobe emphysema and lower-lobe fibrosis, predominantly in older male smokers. Despite often preserved spirometric volumes, patients exhibit severely
Carina Adina Afloarei +7 more
doaj +2 more sources
Combined pulmonary fibrosis and emphysema in a tyre industry worker
We report a case of combined pulmonary fibrosis and emphysema (CPFE) with severe pulmonary hypertension in a 46-year-old man, nonsmoker, tyre industry worker. CPFE is commonly reported to be associated with tobacco smoking.
Vinaya S Karkhanis, J M Joshi
doaj +2 more sources
Rheumatoid arthritis presenting by combined pulmonary fibrosis and emphysema with clubbing and pulmonary hypertension: A rare case report [PDF]
Key Clinical Message A 60‐year‐old male smoker came with dyspnea. A rare condition known as combined pulmonary fibrosis and emphysema (CPFE) was observed on a chest CT scan.
Reza Basiri +2 more
doaj +2 more sources
Combined Pulmonary Fibrosis and Emphysema (CPFE) Clinical Features and Management [PDF]
René Hage,1,2 Fiorenza Gautschi,1,2 Carolin Steinack,1,2 Macé M Schuurmans1,2 1University Hospital Zurich, Division of Pulmonology, Zurich, Switzerland; 2University of Zurich, Faculty of Medicine, Zurich, SwitzerlandCorrespondence: Ren ...
Hage R +3 more
doaj +2 more sources
Pulmonary function measures predict mortality differently in IPF versus combined pulmonary fibrosis and emphysema [PDF]
The composite physiologic index (CPI) was derived to represent the extent of fibrosis on high-resolution computed tomography (HRCT), adjusting for emphysema in patients with idiopathic pulmonary fibrosis (IPF).
Martinez, Fernando J. +13 more
core +5 more sources

