Results 31 to 40 of about 686 (119)
Clinical characteristics of combined pulmonary fibrosis and emphysema [PDF]
, 2010 The definitive version is available at www.blackwell-synergy.comBackground and objective: Patients with combined pulmonary fibrosis and emphysema (CPFE) are sometimes seen, and we speculate that these patients have some different clinical characteristics
Masayuki HANAOKA +11 more
core +1 more source
Respiratory Medicine Case Reports, 2018 Myeloperoxidase antineutrophil cytoplasmic autoantibody (MPO-ANCA) is well-known as a serological marker for small-vessel vasculitis. However, when a smoker with interstitial lung disease (ILD) exhibits serum ANCA positivity without systemic vasculitis ...
Masahiro Nemoto +7 more
doaj +1 more source
Combined pulmonary fibrosis and emphysema
, 2018 Introduction: Pulmonary fibrosis is a disease that is characterized by an accumulation of excess fibrous connective tissue in the interstitium or alveoli. This process is called scarring. The main pathophysiological effect is reduction of oxygen supply
Aleksandrov, Veselin; Medical University of Varna +4 more
core +1 more source
A Case Report of Combined Pulmonary Fibrosis and Emphysema
Amrita Journal of MedicineCombined pulmonary fibrosis and emphysema (CPFE) is an underdiagnosed condition characterized by upper lobe emphysema and lower lobe fibrosis, most often seen in male smokers.
Supriya Adiody, Vishnu Narayanan
doaj +1 more source
Arthritis Research & Therapy, 2021 Background This study aimed to analyze the literature systematically to determine the clinical characteristics and prognosis of patients with connective tissue disease (CTD) with combined pulmonary fibrosis and emphysema (CPFE) compared to those of ...
Bon San Koo +6 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao +7 more
wiley +1 more source
Advanced Science, EarlyView.Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin +5 more
wiley +1 more source
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
The Anatomical Record, EarlyView.Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases [PDF]
Tuberculosis and Respiratory DiseasesInterstitial lung disease (ILD) comprises a heterogeneous group of disorders characterized by interstitial compartment proliferation, inflammatory infiltration, and potential fibrosis with abnormal collagen deposition.
Chul Park +7 more
doaj +1 more source
Arthritis &Rheumatology, Accepted Article.Objective We evaluated baseline characteristics, treatment patterns, and outcomes in patients with systemic autoimmune rheumatic disease‐associated progressive pulmonary fibrosis (SARD‐PPF) and evaluated whether outcomes differed by SARD subtype. Methods The ILD‐PRO Registry is a prospective multicenter US registry of patients with PPF.
Sonali J Bracken +7 more
wiley +1 more source