Results 41 to 50 of about 13,102 (151)

Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE) - Table 2

, 2016
Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE) - Table
Matthias Griese (46185), Andriana I. Papaioannou (361264), Georgia Papadaki (2851979), Aris Spathis (298607), Argyro Mazioti (2851997), Konstantinos Kostikas (361271), Ilias Papanikolaou (2851985), Stelios Loukides (2851982), Ioannis Tomos (2851988), Petros Karakitsos (298619), Effrosyni D. Manali (2851991), Aneza Roussou (2851976), Spyros Papiris (999), Kyriakos Chainis (2851994)   +13 more
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source

Reviewer_2_v.1 – Supplemental material for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone

, 2019
Supplemental material, Reviewer_2_v.1 for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone by Chun-guo Jiang, Qiang Fu and Chun-ming Zheng in Therapeutic Advances in Respiratory ...
Qiang Fu (129583), Chun-guo Jiang (7869566), Chun-ming Zheng (7869569)   +2 more
core   +1 more source

Reviewer_2_v.2 – Supplemental material for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone

, 2019
Supplemental material, Reviewer_2_v.2 for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone by Chun-guo Jiang, Qiang Fu and Chun-ming Zheng in Therapeutic Advances in Respiratory ...
Qiang Fu (129583), Chun-guo Jiang (7869566), Chun-ming Zheng (7869569)   +2 more
core   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

Advanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin, Ping Zhang, Qing Song, Tao Li, Yuqin Zeng, Ping Chen   +5 more
wiley   +1 more source

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases [PDF]

Tuberculosis and Respiratory Diseases
Interstitial lung disease (ILD) comprises a heterogeneous group of disorders characterized by interstitial compartment proliferation, inflammatory infiltration, and potential fibrosis with abnormal collagen deposition.
Chul Park, Yoomi Yeo, A La Woo, Jung Wan Yoo, Goohyeon Hong, Jong Wook Shin, Sung Woo Park, on Behalf of the Korean Interstitial Lung Disease Study Group   +7 more
doaj   +1 more source

Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients

The Anatomical Record, EarlyView.
Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey, Benoît Beyer, Elena García‐Vargas, Isabel Torres‐Sánchez, Francisco García‐Río, Markus Bastir   +5 more
wiley   +1 more source

Author_Response_1 – Supplemental material for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone

, 2019
Supplemental material, Author_Response_1 for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone by Chun-guo Jiang, Qiang Fu and Chun-ming Zheng in Therapeutic Advances in Respiratory ...
Qiang Fu (129583), Chun-guo Jiang (7869566), Chun-ming Zheng (7869569)   +2 more
core   +1 more source

Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE). [PDF]

PLoS ONE, 2016
Emphysema and idiopathic pulmonary fibrosis (IPF) present either per se or coexist in combined pulmonary fibrosis and emphysema (CPFE). Serum surfactant proteins (SPs) A, B, C and D levels may reflect lung damage.
Andriana I Papaioannou, Konstantinos Kostikas, Effrosyni D Manali, Georgia Papadaki, Aneza Roussou, Aris Spathis, Argyro Mazioti, Ioannis Tomos, Ilias Papanikolaou, Stelios Loukides, Kyriakos Chainis, Petros Karakitsos, Matthias Griese, Spyros Papiris   +13 more
doaj   +1 more source