Results 51 to 60 of about 13,102 (151)

Outcomes in Progressive Pulmonary Fibrosis in Systemic Autoimmune Rheumatic Diseases: Real‐World Data From the ILD‐PRO Registry

Arthritis &Rheumatology, EarlyView.
Objective We evaluated baseline characteristics, treatment patterns, and outcomes in patients with systemic autoimmune rheumatic disease–associated progressive pulmonary fibrosis (SARD‐PPF) and evaluated whether outcomes differed by SARD subtype. Methods The ILD‐PRO Registry is a prospective multicenter US registry of patients with PPF.
Sonali J. Bracken, Jeremy M. Weber, Megan L. Neely, Aparna C. Swaminathan, Scott M. Palmer, Erin M. Wilfong, Ann D. Chauffe, Elizabeth R. Volkmann   +7 more
wiley   +1 more source

Reviewer_1_v.1 – Supplemental material for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone

, 2019
Supplemental material, Reviewer_1_v.1 for Prognosis of combined pulmonary fibrosis and emphysema: comparison with idiopathic pulmonary fibrosis alone by Chun-guo Jiang, Qiang Fu and Chun-ming Zheng in Therapeutic Advances in Respiratory ...
Qiang Fu (129583), Chun-guo Jiang (7869566), Chun-ming Zheng (7869569)   +2 more
core   +1 more source

Analysis of external respiratory function disturbances in combined pulmonary fibrosis and emphysema

Терапевтический архив
Aim. To analyze the features of indicators of the external respiration function and their dynamics in patients with a combined pulmonary fibrosis and emphysema (CPFE). Materials and methods.
Nikita V. Markov, Natalia A. Khodorik, Mikhail M. Ilkovich, Lubov N. Novikova, Iuliia D. Rabik, Elena V. Privalova, Nadezhda T. Panina, Alexandr N. Kulikov   +7 more
doaj   +1 more source

Combined pulmonary fibrosis and emphysema

, 2018
Introduction: Pulmonary fibrosis is a disease that is characterized by an accumulation of excess fi­brous connective tissue in the interstitium or alveoli. This process is called scarring. The main patho­physiological effect is reduction of oxygen supply
Aleksandrov, Veselin; Medical University of Varna, Veliev, Denis; Medical University of Varna, Vasileva, Nadejda; Medical University of Varna, Hadjimehmed, Adem; Medical University of Varna, Yankov, Kamen; Medical University of Varna   +4 more
core   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Clinical Outcomes and Acute Exacerbation Incidence in Combined Pulmonary Fibrosis and Emphysema

Respirology, EarlyView.
This multicentre prospective study of 1016 patients demonstrated that CPFE, defined as ≥ 5% emphysema on visual CT assessment, identified a high‐risk phenotype with significantly worse 5‐year survival compared to non‐CPFE IIP patients (51.4% vs. 63.1%) and COPD patients (51.4% vs. 84.0%) and higher acute exacerbation incidence, validating international
Kazuya Tsubouchi, Yasuaki Kotetsu, Tomotsugu Takano, Hiroaki Ogata, Fumiaki Kiyomi, Katsuyuki Ichiki, Shohei Takata, Yasuhiko Kitasato, Hiroshi Ishii, Kazuhiro Yatera, Kei Yamasaki, Masaki Okamoto, Makoto Yoshida, Masayuki Kawasaki, Masaki Fujita, Tomohiro Ogawa, Kazunori Tobino, Eiji Harada, Noriaki Nakagaki, Masashi Komori, Taishi Harada, Hiroshi Wataya, Yoichi Nakanishi, Isamu Okamoto   +23 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Pathological and radiological correlation in an autopsy case of combined pulmonary fibrosis and emphysema [PDF]

, 2015
We report an educational autopsy case of combined pulmonary fibrosis and emphysema. Radiological patterns of the upper lung were considered as mostly emphysema, but pathological observation revealed significant interstitial fibrosis of usual interstitial
Fukuoka, Junya, Tabata K, Otani, Kyoko, Otani K, Hayashi R, Karata, Hiroki, Karata H, Egashira R, Tanaka, Tomonori, Hayashi, Ryuji, Tanaka T, Fukuoka J, Tabata, Kazuhiro, Egashira, Ryoko, Hori, Takashi, Hori T   +15 more
core   +1 more source

Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation

Insights into Imaging, 2019
Cigarettes are well-recognized risk factors responsible for the emergence of a variety of pathologic conditions affecting both the airways and the lungs.
Célia Sousa, Márcio Rodrigues, André Carvalho, Bárbara Viamonte, Rui Cunha, Susana Guimarães, Conceição Souto de Moura, António Morais, José Miguel Pereira   +8 more
doaj   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source