Results 51 to 60 of about 1,188 (177)

Combined Pulmonary Fibrosis and Emphysema (CPFE): A Review of Pathogenesis, Clinical Characteristics, Management and Prognosis

International audienceCombined pulmonary fibrosis and emphysema (CPFE) is a rare but increasingly recognised condition characterised by the simultaneous coexistence of both upper lobe predominant emphysema and diffuse pulmonary fibrosis mainly in the ...
Khanam, Rawshan Arra
openaire   +2 more sources

Clinical Outcomes and Acute Exacerbation Incidence in Combined Pulmonary Fibrosis and Emphysema

Respirology, Volume 31, Issue 11, Page 1117-1125, November 2026.
This multicentre prospective study of 1016 patients demonstrated that CPFE, defined as ≥ 5% emphysema on visual CT assessment, identified a high‐risk phenotype with significantly worse 5‐year survival compared to non‐CPFE IIP patients (51.4% vs. 63.1%) and COPD patients (51.4% vs. 84.0%) and higher acute exacerbation incidence, validating international
Kazuya Tsubouchi, Yasuaki Kotetsu, Tomotsugu Takano, Hiroaki Ogata, Fumiaki Kiyomi, Katsuyuki Ichiki, Shohei Takata, Yasuhiko Kitasato, Hiroshi Ishii, Kazuhiro Yatera, Kei Yamasaki, Masaki Okamoto, Makoto Yoshida, Masayuki Kawasaki, Masaki Fujita, Tomohiro Ogawa, Kazunori Tobino, Eiji Harada, Noriaki Nakagaki, Masashi Komori, Taishi Harada, Hiroshi Wataya, Yoichi Nakanishi, Isamu Okamoto   +23 more
wiley   +1 more source

A newly-defined entity: combined pulmonary fibrosis and emphysema syndrome

, 2015
Combined pulmonary fibrosis and emphysema (CPFE) syndrome is a rare disease characterized with shortness of breath, upper lobe emphysema, lower lobe fibrosis and impairment of gas exchange.
Ozcelik, Neslihan, Ozsu, Savas
core   +1 more source

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

Histopathology, Volume 89, Issue 3, Page 403-425, September 2026.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson, Wendy A. Cooper, Aurelie Fabre, William Travis, Lida P. Hariri, Ayodeji Adegunsoye, Sara Piciucchi, Christopher J Ryerson   +7 more
wiley   +1 more source

Idiopathic Pulmonary Fibrosis update, comparing the Australasian Interstitial Lung Disease Registry to the Australian Idiopathic Pulmonary Fibrosis Registry

Internal Medicine Journal, Volume 56, Issue 9, Page 1518-1527, September 2026.
Abstract Background and aims Real‐world evaluation of clinical characteristics and treatment profile of patients with idiopathic pulmonary fibrosis (IPF) is needed to establish areas for improvement according to evidence‐based recommendations. This study evaluated the clinical characteristics and treatment profile of patients with IPF from the ...
Michelle Chee, Yet Hong Khor, Dan Jackson, Wendy Cooper, Jason D’Costa, Sally de Boer, Adrienne Edwards, Samantha Ellis, Eli Gabbay, Henry Gallagher, Ian Glaspole, Nicole Goh, Christopher Grainge, Peter Hopkins, Gregory Keir, Benjamin Kwan, John Mackintosh, Yuben Moodley, Irene Moore, Vidya Navaratnam, Chong Ong, Paul Reynolds, Karen Royals, Alan Teoh, Lauren Troy, Elizabeth Veitch, Margaret Wilsher, Jeremy Wrobel, Chris Zappala, Tamera Corte, Francis Thien, on behalf of the AILDR Steering Committee   +31 more
wiley   +1 more source

Differentiating Smoking-Related Interstitial Fibrosis (SRIF) from Usual Interstitial Pneumonia (UIP) with Emphysema Using CT Features Based on Pathologically Proven Cases. [PDF]

PLoS ONE, 2016
To differentiate smoking-related interstitial fibrosis (SRIF) from usual interstitial pneumonia (UIP) with emphysema on CT in combined pulmonary fibrosis and emphysema (CPFE) patients.This study was approved by the institutional review board and informed
Kum Ju Chae, Gong Yong Jin, Hyun Nyeong Jung, Keun Sang Kwon, Hyemi Choi, Yong Chul Lee, Myoung Ja Chung, Ho Sung Park   +7 more
doaj   +1 more source

Combined pulmonary fibrosis and emphysema

, 2018
Introduction: Pulmonary fibrosis is a disease that is characterized by an accumulation of excess fi­brous connective tissue in the interstitium or alveoli. This process is called scarring. The main patho­physiological effect is reduction of oxygen supply
Aleksandrov, Veselin; Medical University of Varna, Veliev, Denis; Medical University of Varna, Vasileva, Nadejda; Medical University of Varna, Hadjimehmed, Adem; Medical University of Varna, Yankov, Kamen; Medical University of Varna   +4 more
core   +1 more source

Serum levels of surfactant proteins in patients with combined pulmonary fibrosis and emphysema (CPFE) [PDF]

1.5 Diffuse Parenchymal Lung Disease, 2015
Introduction: Emphysema and idiopathic pulmonary fibrosis(IPF) are defined by different clinical, functional, radiological, and pathological criteria that coexist in CPFE. Serum surfactant protein(SP) levels increase in patients with COPD and IPF and correlate to disease severity.
Andriana Papaioannou, Konstantinos Kostikas, Georgia Papadaki, Aneza Roussou, Aris Spathis, Argyro Mazioti, Ioannis Tomos, Effrosyni Manali, Stelios Loukides, Petros Karakitsos, Spyros Papiris, Filia Diamantea   +11 more
openaire   +1 more source

Noninvasive Gas Exchange Determinants of Exercise Hemodynamics in Non‐Severe Pulmonary Hypertension Associated With Interstitial Lung Disease

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Level 3 cardiopulmonary exercise testing (CPET) can unmask the dynamic burden of pulmonary vascular disease (PVD), while submaximal exercise testing offers a simpler, noninvasive alternative. Emerging markers such as a gas‐exchange derived estimate of pulmonary vascular capacitance (GXCAP) and ventilatory efficiency (VE/VCO2) may reflect PVD ...
Chebly Dagher, Niala Moallem, Garrett Fiscus, Brett Carollo, Kristen Swanson, Harrison W. Farber, Raj Parikh   +6 more
wiley   +1 more source

Objective quantitative multidetector computed tomography assessments in patients with combined pulmonary fibrosis with emphysema: Relationship with pulmonary function and clinical events.

PLoS ONE, 2020
BackgroundCombined pulmonary fibrosis with emphysema (CPFE) is a clinically meaningful syndrome characterized by coexisting upper-lobe emphysema and lower-lobe interstitial fibrosis.
Masaki Suzuki, Naoko Kawata, Mitsuhiro Abe, Hajime Yokota, Rie Anazawa, Yukiko Matsuura, Jun Ikari, Shin Matsuoka, Kenji Tsushima, Koichiro Tatsumi   +9 more
doaj   +2 more sources