Results 111 to 120 of about 51,303 (237)

Do Gadolinium‐Based Contrasts Represent a High Risk for Genotoxicity in Mammalian Cells? A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT The scientific rationale for this review stems from the increasing global use of gadolinium‐based contrast agents in medical imaging and the concerns over the long‐term environmental accumulation of gadolinium waste, which may pose biological risks.
Thiago Guedes Pinto, Rogerio Aparecido Dedivits, Daniel Araki Ribeiro   +2 more
wiley   +1 more source

Multi‐Scale Analysis of Regional Pathology in the Human Trapezium During Osteoarthritis Progression

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Trapeziometacarpal (TMC) osteoarthritis (OA) is a prevalent condition that significantly impacts hand function and quality of life. In this study we sought to close gaps in knowledge related to the initiation and progression of TMC OA on the tissue scale by evaluating the morphology and gross appearance, wear patterns, mechanical properties ...
Brendan D. Stoeckl, Kendall M. Masada, Lorielle G. Laforest, Hannah H. Lee, Robert L. Mauck, David R. Steinberg   +5 more
wiley   +1 more source

Development of a Core Outcome Set for Intervention Studies in Adults With Laryngotracheal Stenosis

The Laryngoscope, EarlyView.
We used a rigorous two round Delphi process informed by multiple stakeholder groups to gain consensus on seven core outcomes for inclusion in future research relating to adults with laryngotracheal stenosis. Use of this core outcome set will standardise outcomes measured in future research studies, ensuring they are comparable. ABSTRACT Objective Adult
Gemma M. Clunie, Amy Freeman‐Sanderson, Chadwan Al‐Yaghchi, Justin W. G. Roe, Caroline Alexander, Guri Sandhu, Alison McGregor, Louise Rose   +7 more
wiley   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Genotoxic Potential of Thymol on Honey Bee DNA in the Comet Assay. [PDF]

Insects, 2023
Glavinić U, Rajković M, Ristanić M, Stevanović J, Vejnović B, Djelić N, Stanimirović Z.   +6 more
europepmc   +1 more source

Deoxyribonucleic acid damage in Iranian veterans 25 years after wartime exposure to sulfur mustard [PDF]

, 2013
• Background: More than 100,000 Iranian veterans and civilians still suffer from various long-term complications due to their exposure to sulfur mustard (SM) during the Iran–Iraq war in 1983–88. The aim of the study was to investigate DNA damage of SM in
Balali-Mood, Mahdi, Behravan, Effat, Blain, Peter G., Jowsey, Paul, Khateri, Shahriar, Maraghi, Elham, Moallem, Seyed Adel   +6 more
core   +3 more sources

Differential Effects of Wild Blueberry (Poly)Phenol Metabolites in Modulating Lipid Metabolism and Oxidative Stress in 3T3‐L1 Adipocytes

Molecular Nutrition &Food Research, EarlyView.
Metabolites derived from wild blueberry (poly)phenols, such as syringic (SA), vanillic (VA), and isoferulic acids (IA), can modulate lipid metabolism and oxidative stress markers in mature 3T3‐L1 adipocytes treated with free fatty acids (FFAs; oleic/palmitic acid, 750 µM, 2:1 ratio).
Samuele Venturi, Marco Rendine, Mirko Marino, Dorothy Klimis‐Zacas, Patrizia Riso, Cristian Del Bo'   +5 more
wiley   +1 more source

Measuring DNA modifications with the comet assay: a compendium of protocols. [PDF]

Nat Protoc, 2023
Collins A, Møller P, Gajski G, Vodenková S, Abdulwahed A, Anderson D, Bankoglu EE, Bonassi S, Boutet-Robinet E, Brunborg G, Chao C, Cooke MS, Costa C, Costa S, Dhawan A, de Lapuente J, Bo' CD, Dubus J, Dusinska M, Duthie SJ, Yamani NE, Engelward B, Gaivão I, Giovannelli L, Godschalk R, Guilherme S, Gutzkow KB, Habas K, Hernández A, Herrero O, Isidori M, Jha AN, Knasmüller S, Kooter IM, Koppen G, Kruszewski M, Ladeira C, Laffon B, Larramendy M, Hégarat LL, Lewies A, Lewinska A, Liwszyc GE, de Cerain AL, Manjanatha M, Marcos R, Milić M, de Andrade VM, Moretti M, Muruzabal D, Novak M, Oliveira R, Olsen AK, Owiti N, Pacheco M, Pandey AK, Pfuhler S, Pourrut B, Reisinger K, Rojas E, Rundén-Pran E, Sanz-Serrano J, Shaposhnikov S, Sipinen V, Smeets K, Stopper H, Teixeira JP, Valdiglesias V, Valverde M, van Acker F, van Schooten FJ, Vasquez M, Wentzel JF, Wnuk M, Wouters A, Žegura B, Zikmund T, Langie SAS, Azqueta A.   +78 more
europepmc   +1 more source

Gas Chromatography‐Mass Spectrometry Analysis, Genoprotective, and Antioxidant Potential of Curio radicans (L. f.) P.V. Heath

ChemistryOpen, EarlyView.
The ethyl acetate extract of Curio radicans is found to contain a higher proportion of bioactive compounds (55% vs 30% in the ethanolic extract) by gas chromatography‐mass spectrometry, and it exhibits stronger antioxidant activity in the DPPH assay (75% vs 65% inhibition) as well as clear genoprotective effects against H2O2‐induced DNA damage ...
Muhammad Naseer, Muhammad Adil, Sarir Ahmad, Mikhlid H. Almutairi, Abdulwahed Fahad Alrefaei, Sajid Ali, Fayaz Asad   +6 more
wiley   +1 more source

Outcomes of periodontal therapy: Strengthening the relevance of research to patients. A co‐created review

Periodontology 2000, EarlyView., 2023
Abstract Periodontitis is a long‐term condition affecting up to half of the population globally and causing significant impacts on life quality. Successful management depends on taking life‐long ownership of the condition by those affected. There is a wealth of research to inform on management options. However, most of the research has been designed by
Ian Needleman, Neil Almond, Natalie Leow, Jim Phillips   +3 more
wiley   +1 more source