Results 221 to 230 of about 51,303 (237)

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, Volume 5, Issue 6, June 2025.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Sustainable Water Decontamination: Advanced High‐Valent Iron Active Species‐Driven Peroxymonosulfate Activation for Global Challenges

CleanMat, Volume 2, Issue 2, Page 88-103, June 2025.
Iron‐based catalysts activate peroxymonosulfate (PMS) to generate high‐valent iron‐oxo species for water decontamination and clean water production. The activation efficiency of PMS varies significantly depending on iron catalyst properties, while the generation of reactive high‐valent iron intermediates is governed by catalyst characteristics ...
Junpeng Guo, Miao Lei, Ling Yan, Junhang Huang, Chang Liu, Li Ye, BoLin Li, Xingtao Xu, Ye Li   +8 more
wiley   +1 more source

Stereotactic Body Radiation Therapy for Oligometastatic Recurrent Esophageal Squamous Cell Carcinoma: A Retrospective Cohort Study From a Single Tertiary Center

Cancer Reports, Volume 8, Issue 6, June 2025.
ABSTRACT Background Oligometastatic disease, characterized by a limited number of metastatic lesions, has gained significant attention for its potential to enable long‐term survival with definitive local therapies. Esophageal cancer, an aggressive malignancy often diagnosed at advanced stages, carries a poor prognosis, particularly in cases involving ...
Atsuto Katano, Masanari Minamitani, Shingo Ohira, Subaru Sawayanagi, Hideomi Yamashita   +4 more
wiley   +1 more source

Modeling cancer–microbiome interactions in vitro: A guide to co‐culture platforms

International Journal of Cancer, Volume 156, Issue 11, Page 2053-2067, 1 June 2025.
Abstract The biology of cancer is characterized by an intricate interplay of cells originating not only from the tumor mass, but also its surrounding environment. Different microbial species have been suggested to be enriched in tumors and the impacts of these on tumor phenotypes is subject to intensive investigation.
Kamil Moskal, Nimisha Khurana, Luisa Siegert, Ye Seul Lee, Hans Clevers, Eran Elinav, Jens Puschhof   +6 more
wiley   +1 more source

The microbiologist's guide to metaproteomics

iMeta, Volume 4, Issue 3, June 2025.
Metaproteomics within the multi‐omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs), mapping protein–protein interactions (PPIs), and localizing proteins.
Tim Van Den Bossche, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley‐Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, Daniel Figeys, Lucia Grenga, Timothy J. Griffin, Céline Henry, Robert L. Hettich, Tanja Holstein, Pratik D. Jagtap, Nico Jehmlich, Jonghyun Kim, Manuel Kleiner, Benoit J. Kunath, Xuxa Malliet, Lennart Martens, Subina Mehta, Bart Mesuere, Zhibin Ning, Alessandro Tanca, Sergio Uzzau, Pieter Verschaffelt, Jing Wang, Paul Wilmes, Xu Zhang, Xin Zhang, Leyuan Li, The Metaproteomics Initiative   +31 more
wiley   +1 more source

Gut‐derived Lactobacillus from exceptional responders mitigates chemoradiotherapy‐induced intestinal injury through methionine‐driven epigenetic modulation

iMeta, Volume 4, Issue 3, June 2025.
Using metagenomic sequencing and bioinformatics analysis of fecal samples from rectal cancer patients and corresponding mouse models, our study identifies a strong association between Lactobacillus abundance and acute chemoradiotherapy‐induced intestinal injury (ACRIII). Elevated Lactobacillus levels before treatment were consistently linked to reduced
Lu Yu, Zhenhui Chen, Shengqi Yin, Qiqing Guo, Yuchuan Chen, Jiaying Li, Yafang Wang, Xiangqiang Liu, Zi Xu, Yaowei Zhang, Yuqin Zhang, Zhihao Zheng, Keli Chen, Yanqing Ding, Hongying Fan, Zhifeng Liu, Yi Ding   +16 more
wiley   +1 more source

Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depletion

IUBMB Life, Volume 77, Issue 6, June 2025.
ABSTRACT Serum tyrosine and phenylalanine levels increase during aging and age‐associated disorders. We previously showed that tyrosyl‐tRNA synthetase (TyrRS/YARS1) is reduced in Alzheimer's Disease (AD) brains, and tyrosine and phenylalanine decrease TyrRS in neurons. Here, we found that tau is a negative regulator, whereas estrogen and leucine act as
Megha Jhanji, Ashita Bhan, Colin Arrowood, Dina W. Yakout, Ankit Shroff, Danielle McManus, Henrietta Gifford, Janay Vacharasin, Sofia B. Lizarraga, Taras Y. Nazarko, Angela M. Mabb, Mathew Sajish   +11 more
wiley   +1 more source

Intradiscal Mesenchymal Stromal Cell Therapy for the Treatment of Low Back Pain Due to Moderate‐to‐Advanced Multilevel Disc Degeneration: A Preliminary Report of a Double‐Blind, Phase IIB Randomized Clinical Trial (DREAM Study)

JOR SPINE, Volume 8, Issue 2, June 2025.
This phase IIB randomized controlled trial evaluated the safety and efficacy of intradiscal injections of autologous bone marrow‐derived mesenchymal stromal cells (BM‐MSCs) in patients with chronic low back pain from moderate‐to‐advanced multilevel disc degeneration.
Gianluca Vadalà, Fabrizio Russo, Cristiana Lavazza, Giorgia Petrucci, Luca Ambrosio, Silvia Budelli, Elisa Montelatici, Giuseppina Di Giacomo, Claudia Cicione, Veronica Tilotta, Giuseppe Francesco Papalia, Matteo Pileri, Amalia Bruno, Salvatore La Rosa, Emilio Carrino, Eliodoro Faiella, Massimiliano Carassiti, Lorenza Lazzari, Rocco Papalia, Vincenzo Denaro   +19 more
wiley   +1 more source

The crisis of scientific paradigm in modern psychiatry and a look to the future

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.
Abstract Contemporary psychiatry is going through times of crisis. In this article, I will focus on the epistemological and historical aspect of the phenomenon. Three authors are the main references guiding the argumentation I offer in this text. They are Thomas Kuhn, Georges Lanteri‐Laura and Juan Carlos Stagnaro.
Santiago A. Levín
wiley   +1 more source

Modeling Cut Rose Yield Over an 18‐Month Period After Compost Amendment Using Repeated Sigmoidal Gompertz Curve Fitting

Plant-Environment Interactions, Volume 6, Issue 3, June 2025.
ABSTRACT Understanding the growth, development, and production patterns of perennial crops is crucial for optimizing agricultural practices and enhancing crop productivity. Growth models are valuable tools in this regard, offering insights into how crops respond to different experimental treatments.
E. A. de Nijs, A. Tietema, R. Bol, E. E. van Loon   +3 more
wiley   +1 more source