Results 51 to 60 of about 1,981,264 (328)
Controlling variation in the comet assay
Frontiers in Genetics, 2014 Variability of the comet assay is a serious issue, whether it occurs from experiment to experiment in the same laboratory, or between different laboratories analysing identical samples.
Andrew Richard Collins +5 more
doaj +1 more source
The Comet Assay as a Tool to Detect the Genotoxic Potential of Nanomaterials
Nanomaterials, 2019 The interesting physicochemical characteristics of nanomaterials (NMs) has brought about their increasing use and, consequently, their increasing presence in the environment.
A. García-Rodríguez +6 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay
International Journal of Molecular Sciences, 2019 Single cell gel electrophoresis, also known as the comet assay, has become a widespread DNA damage assessment tool due to its sensitivity, adaptability, low cost, ease of use, and reliability.
M. Karbaschi +8 more
semanticscholar +1 more source
The comet assay: past, present, and future [PDF]
Frontiers in Genetics, 2015 The alkaline comet assay (single cell gel electrophoresis) is the most widely used method for measuring DNA damage in eukaryotic cells (Neri et al., 2015). It detects strand breaks (SBs) and alkali-labile sites at frequencies from a few hundred to several thousand breaks per cell—a biologically useful range, extending from low endogenous damage levels ...
Langie, Sabine A. S. +2 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre +3 more
wiley +1 more source
Comet assay on mice testicular cells
Frontiers in Genetics, 2015 Heritable mutations may result in a variety of adverse outcomes including genetic disease in the offspring. In recent years the focus on germ cell mutagenicity has increased and the “Globally Harmonized System of Classification and Labelling of ...
Anoop Kumar Sharma
doaj +1 more source
Advanced Materials, EarlyView.A recombinant spider silk protein was functionalized by incorporating genetically encoded bio‐orthogonal reactive azido‐groups. The azido‐functionalized proteins were produced in a scalable biotechnological process, and particles, films, as well as nanofibers were established as anchorage for fully functional antibodies via site‐specific bio‐orthogonal
Claudia Lacombe +4 more
wiley +1 more source
Epithelial cells as alternative human biomatrices for comet assay
Frontiers in Genetics, 2014 The comet assay is a valuable experimental tool aimed at mapping DNA damage in human cells in vivo for environmental and occupational monitoring, as well as for therapeutic purposes, such as storage prior to transplant, during tissue engineering, and in ...
Emilio eRojas +4 more
doaj +1 more source
The Effect of Obstructive Sleep Apnea on DNA Damage and Oxidative Stress [PDF]
Clinical and Experimental Otorhinolaryngology, 2013 ObjectivesObstructive sleep apnea syndrome (OSAS) is associated with repeated hypoxia and re-oxygenation. This characteristic of OSAS may cause oxidative stress and DNA damage.
Il Gyu Kang, Joo Hyun Jung, Seon Tae Kim
doaj +1 more source