Results 161 to 170 of about 111,659 (285)

Active surveillance of drug safety in healthcare data: Sequential monitoring of bacterial and serious urinary tract infection risk in sodium‐glucose cotransporter 2 inhibitor users

British Journal of Clinical Pharmacology, EarlyView.
Abstract Introduction Active surveillance of adverse events using healthcare data is emerging as complementary to the monitoring of spontaneous reports and stand‐alone pharmacoepidemiologic studies. The risk of urinary tract infections (UTIs) was listed as a special warning for sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) when marketed in Europe
Haoxin Le, Dilsad Simay Peker, Lukas Frederic Westphal, Nikolai Brun, Christine Erikstrup Hallgreen, Morten Andersen   +5 more
wiley   +1 more source

Genetic Analysis of Patients With Common Variable Immunodeficiency Followed in the Pulmonology Department: A Report of Five Patients. [PDF]

Cureus
Boumekrat L, Bouhamdi A, Elmakhzan B, Aalil S, Es-Sabbahi B, Senhaji L, Karhate M, Serraj M, ElBiaze M, Benjelloun MC, Amara B.   +10 more
europepmc   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Characteristics of the patients followed with the diagnosis of common variable immunodeficiency and the complications

Central European Journal of Immunology, 2019
Semiha Bahceci Erdem, Nesrin Gulez, Ferah Genel, Sait Karaman, Hikmet T. Nacaroglu   +4 more
doaj   +1 more source

Pulmonary embolism and aseptic meningitis complicating IVIG for common variable immunodeficiency syndrome. [PDF]

J Allergy Clin Immunol Glob
Butz D, Adlakha A.
europepmc   +1 more source

Common variable immunodeficiency in a 13-year-old Thoroughbred mare

, 2012
This report describes the clinical progression of a Thoroughbred mare with common variable immunodeficiency (CVID). Equine CVID is a primary immunodeficiency characterized by late-onset B cell lymphopenia or depletion, hypo- or agammaglobulinemia, and ...
Jager, Mason
core  

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source

Liver Disease in Common Variable Immunodeficiency: Current Evidence and Knowledge Gaps. [PDF]

Int J Mol Sci
Nedelea I, Nicoara-Farcau O, Procopet B, Stefanescu H, Radu C, Balan R, Fit AM, Rusu I, Deleanu D.   +8 more
europepmc   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen, Mathilde Rønne Koch, Cecilie Utke Rank, Christen Lykkegaard Andersen, Allan Weimann, Maria Thastrup, Tianwu Yang, Trine Meldgaard Lund, Ib Jarle Christensen, Flemming Nielsen, Tore Bjerregaard Stage, Sara Bisgaard Jensen, Mette Klarskov Andersen, Kjeld Schmiegelow, Kim Dalhoff   +14 more
wiley   +1 more source

Concurrent hereditary angioedema type I and common variable immunodeficiency presenting as suspected antibiotic hypersensitivity: Case report and literature discussion. [PDF]

World Allergy Organ J
Urdea D, Mereuta DV, Iorga RE, Pavel-Tanasa M.   +3 more
europepmc   +1 more source