Results 181 to 190 of about 111,659 (285)

Antimicrobial use on <i>Campylobacter</i> revealed by next-generation sequencing in patients with common variable immunodeficiency. [PDF]

Front Microbiol
Jehanne Q, Conrad A, Josserand RN, Benech N, Schatz PM, Bénéjat L, Ducournau A, Aptel J, Martin M, Jauvain M, Dauwalder O, Lehours P.   +11 more
europepmc   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Standing Still: A Case of Stiff Person Syndrome and Common Variable Immunodeficiency. [PDF]

Cureus
Khazar V, Escobar S, Kim J, McClain S, Szema AM.   +4 more
europepmc   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Common Variable Immunodeficiency

Immunology and Allergy Clinics of North America, 2015
Jordan K. Abbott, Erwin W. Gelfand
openaire   +2 more sources

Investigating serum free light chains in patients with common variable immunodeficiency disorder in compare with other immunodeficiency diseases. [PDF]

Sci Rep
Bemanian MH, Khoshmirsafa M, Ahmadi M, Nabavi M, Arshi S, Chavoshzadeh Z, Shokri S, Fallahpour M, Jafariaghdam N, Afrashteh F, Asefi S, Mesdaghi M, Sharafian S.   +12 more
europepmc   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Heterozygous NFKB1 variant causes inflammatory dysregulation shaped by broader genetic context in common variable immunodeficiency. [PDF]

JCI Insight
Hayes KM, Boldt K, Schnorr PJ, Bawa P, Abyazi ML, Ware MS, Gyimesi G, James M, Ko HM, Cunningham-Rundles C, Mizgerd JP, Mostoslavsky G, Kotton DN, Maglione PJ.   +13 more
europepmc   +1 more source

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source