Results 271 to 280 of about 80,578 (289)

Comparative genomic hybridization and prenatal diagnosis

Current Opinion in Obstetrics & Gynecology, 2006
Microarray-based comparative genomic hybridization (array-CGH) which detects aneuploidies and submicroscopic deletions and duplications in one assay is now offered for genetic diagnosis in children and adults. Its application to prenatal diagnosis is still limited, but very promising.
Ignatia B, Van den Veyver, Arthur L, Beaudet   +1 more
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[CGH (comparative genomic hybridization)].

Nihon rinsho. Japanese journal of clinical medicine, 1996
Comparative Genomic Hybridization (CGH) is a powerful new method which allows genome-wide mapping of regions with DNA sequence copy number changes (both increases and decreases) in a single experiment without previous knowledge of the locations of the regions of abnormality.
M, Sakamoto, H, Sakamoto, Y, Suehiro, T, Akiya, H, Iwabuchi, H, Sakunaga, T, Muroya, T, Noda, T, Sugishita, Y, Tenjin   +9 more
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Quantitative analysis of comparative genomic hybridization

Cytometry, 1995
AbstractComparative genomic hybridization (CGH) is a new molecular cytogenetic method for the detection of chromosomal imbalances. Following cohybridization of DNA prepared from a sample to be studied and control DNA to normal metaphase spreads, probes are detected via different fluorochromes.
S, du Manoir, E, Schröck, M, Bentz, M R, Speicher, S, Joos, T, Ried, P, Lichter, T, Cremer   +7 more
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Array-Based Comparative Genomic Hybridization (aCGH)

2016
Copy number variations (CNVs) in the genomes have been suggested to play important roles in human evolution, genetic diversity, and disease susceptibility. A number of assays have been developed for the detection of CNVs, including fluorescent in situ hybridization (FISH), array-based comparative genomic hybridization (aCGH), PCR-based assays, and next-
Zhang, Chengsheng, Cerveira, Eliza, Romanovitch, Mallory, Zhu, Qihui   +3 more
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Comparative Genomic Hybridization of Wilms’ tumor

2013
Cytogenetic analysis of solid tumors including Wilms' tumor is challenging due to poor chromosome morphology, complexity of abnormalities, and to the possibility of stromal cell overgrowth in tissue culture. Molecular cytogenetic techniques such as chromosomal comparative genomic hybridization (CGH) have improved the diagnosis of chromosomal ...
Shahrad Rod, Rassekh, Evica, Rajcan-Separovic   +1 more
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[Comparative genomic hybridization(CGH)].

Human cell, 1994
A new molecular cytogenetic method, comparative genomic hybridization(CGH), was reviewed. CGH produces a map of DNA sequence copy number on a normal metaphase spread after hybridization with the mixture of tumor DNA and normal reference DNA, which are detected with different fluorochromes, respectively.
M, Matsuta, I, Nishiya
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Array Comparative Genomic Hybridization in Osteosarcoma

2013
Osteosarcoma, the most frequent primary bone tumor, is a malignant mesenchymal sarcoma with a peak incidence in young children and adolescents. Left untreated, it progresses relentlessly to local and systemic disease, ultimately leading to death within months.
Bekim, Sadikovic, Paul C, Park, Shamini, Selvarajah, Maria, Zielenska   +3 more
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Comparative Genomic Hybridization on Single Cells

2007
Comparative genomic hybridization (CGH) is a molecular cytogenetic technique developed for the analysis of chromosome imbalance in tumors and constitutional chromosome abnormalities. It is based on the analysis of genomic DNA and has the advantage over conventional karyotyping in that it does not require that metaphase chromosomes be obtained from the ...
Lucille, Voullaire, Leeanda, Wilton
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Comparative Genomic Hybridization Analysis

2003
Binaifer R, Balsara, Jianming, Pei, Joseph R, Testa   +2 more
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Array Comparative Genomic Hybridization in Pathology

2008
Comparative genomic hybridization (CGH) is a molecular cytogenetic method for the detection and mapping of chromosomal gains and losses.1 It is based on the cohybridization of differentially labeled test and reference DNAs onto metaphase spreads, which usually have been prepared from peripheral blood lymphocytes of a healthy donor. The signal intensity
openaire   +3 more sources