The role of competing endogenous RNA network in the development of hepatocellular carcinoma: potential therapeutic targets. [PDF]
Front Cell Dev BiolThe current situation of hepatocellular carcinoma (HCC) management is challenging due to its high incidence, mortality, recurrence and metastasis. Recent advances in gene genetic and expression regulation have unveiled the significant role of non-coding ...
Tang Z +5 more
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Revealing Landscape of Competing Endogenous RNA Networks in Sepsis-Induced Cardiovascular Diseases [PDF]
Reviews in Cardiovascular Medicine, 2023 Cardiovascular dysfunction induced by sepsis is one of the most common phenotypes of cardiovascular diseases (CVDs), which is closely related to the high mortality of sepsis and is an urgent health problem to be solved worldwide. Unfortunately, the exact
Wei Xiong +4 more
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Competing endogenous RNA networks and ferroptosis in cancer: novel therapeutic targets [PDF]
Cell Death and DiseaseAs a newly identified regulated cell death, ferroptosis is a metabolically driven process that relies on iron and is associated with polyunsaturated fatty acyl peroxidation, elevated levels of reactive oxygen species (ROS), and mitochondrial damage. This
Fatemeh Nejadi Orang +1 more
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Competing Endogenous RNA Networks in Glioma
Frontiers in Genetics, 2021 Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high ...
Liang Cen +9 more
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Competing Endogenous RNA: The Key to Posttranscriptional Regulation [PDF]
The Scientific World Journal, 2014 Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA.
Rituparno Sen +4 more
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Competing endogenous RNA networks in ovarian cancer [PDF]
EXCLI Journal : Experimental and Clinical SciencesEpithelial ovarian cancer is responsible for the majority of ovarian malignancies, and its highly invasive nature and chemoresistant development have been major obstacles to treating patients with mainstream treatments.
Roghaiyeh Derogar +2 more
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Role of circular RNA as competing endogenous RNA in ovarian cancer (Review). [PDF]
Int J Mol MedCircular RNA (circRNA), a type of non-coding RNA, plays a regulatory role in biological processes. The special loop structure of circRNA makes it highly stable and specific in diseased tissues and cells, especially in tumors.
Ye W, Xiang N, Wang Q, Lu Y.
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Scientific Reports, 2021 Schizophrenia (SCZ) is a serious psychiatric condition with a 1% lifetime risk. SCZ is one of the top ten global causes of disabilities. Despite numerous attempts to understand the function of genetic factors in SCZ development, genetic components in SCZ
Hani Sabaie +7 more
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Flavonoids Inhibit Cancer by Regulating the Competing Endogenous RNA Network
Frontiers in Oncology, 2022 Flavonoids are present in a wide range of plants. They have been used in the treatment of cancer, but the mechanism underlying this activity is unclear.
Chengshun Li +6 more
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Construction of a circular RNA-based competing endogenous RNA network to screen biomarkers related to intervertebral disc degeneration [PDF]
BMC Musculoskeletal Disorders, 2022 Highlights 1. An IDD-related ceRNA network involving four circRNAs, three miRNAs and 11 mRNAs was constructed. 2. The expression levels of miR-185-5p, miR-486-5p, FOXO1, SMAD2 and TGFB1 were consistent in different databases. 3.
Bin Yu +10 more
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