Results 1 to 10 of about 351,891 (343)

Competing Endogenous RNA Networks in Glioma [PDF]

Frontiers in Genetics, 2021
Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high ...
Liang Cen, Liang Cen, Ruochen Liu, Ruochen Liu, Wei Liu, Wei Liu, Qianqian Li, Hongjuan Cui, Hongjuan Cui, Hongjuan Cui   +9 more
doaj   +4 more sources

Role of circular RNA as competing endogenous RNA in ovarian cancer (Review). [PDF]

Int J Mol Med
Circular RNA (circRNA), a type of non-coding RNA, plays a regulatory role in biological processes. The special loop structure of circRNA makes it highly stable and specific in diseased tissues and cells, especially in tumors.
Ye W, Xiang N, Wang Q, Lu Y.
europepmc   +4 more sources

Competing endogenous RNA networks and ferroptosis in cancer: novel therapeutic targets [PDF]

Cell Death and Disease
As a newly identified regulated cell death, ferroptosis is a metabolically driven process that relies on iron and is associated with polyunsaturated fatty acyl peroxidation, elevated levels of reactive oxygen species (ROS), and mitochondrial damage. This
Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +1 more
doaj   +3 more sources

Kinetic modelling of competition and depletion of shared miRNAs by competing endogenous RNAs [PDF]

, 2018
Non-conding RNAs play a key role in the post-transcriptional regulation of mRNA translation and turnover in eukaryotes. miRNAs, in particular, interact with their target RNAs through protein-mediated, sequence-specific binding, giving rise to extended ...
A Arvey, A Baccarini, A Fatica, A Franks, A Helwak, A Joshi, A Loinger, A Martirosyan, A Martirosyan, A Nadal, A Raveh, A Re, A Riba, A Sanchez, A Sanchez-Mejias, AD Bosson, AK Leung, AM Gurtan, AS Flynt, B Du, B Obermayer, C Bosia, C Bosia, C Bosia, CW Hsu, D Baek, D Kim, DP Bartel, DP Bartel, DP Bartel, DT Gillespie, E Anastasiadou, E Berezikov, E Koller, E Levine, E Levine, FA Karreth, G Tkacik, H Liang, H Teimouri, I Alvarez-Garcia, I Bose, I Legnini, J Breda, J Das, J Fiorentino, J Kwon, J Noorbakhsh, J Tsang, JM Franco-Zorrilla, JM Schmiedel, L López-Maury, L Salmena, L Tsimring, M Chekulaeva, M Figliuzzi, M Figliuzzi, M Gerstein, M Jens, M Klein, M Mauri, M Nitzan, M Osella, M Osella, M Samoilov, MA Gibson, MA Valencia-Sanchez, MS Ebert, MS Ebert, NG Kampen Van, P Flondor, P Mehta, P Sumazin, PB Detwiler, PS Swain, R Denzler, R Denzler, RC Brewster, RC Friedman, RI Gregory, S Djuranovic, S Grigolon, S Guil, S Jonas, S Mukherji, S Pitchiaya, S Sass, S Wang, SD Chandradoss, TB Hansen, TR Cech, U Ala, U Alon, V Siciliano, X Lai, X Wang, X Yuan, Y Liang, Y Shimoni, Y Tay, Y Tay, Y Yuan   +101 more
core   +8 more sources

Competing endogenous RNA networks in ovarian cancer [PDF]

EXCLI Journal : Experimental and Clinical Sciences
Epithelial ovarian cancer is responsible for the majority of ovarian malignancies, and its highly invasive nature and chemoresistant development have been major obstacles to treating patients with mainstream treatments.
Roghaiyeh Derogar, Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +2 more
doaj   +2 more sources

The role of competing endogenous RNA network in the development of hepatocellular carcinoma: potential therapeutic targets. [PDF]

Front Cell Dev Biol
The current situation of hepatocellular carcinoma (HCC) management is challenging due to its high incidence, mortality, recurrence and metastasis. Recent advances in gene genetic and expression regulation have unveiled the significant role of non-coding ...
Tang Z, Li X, Zheng Y, Liu J, Liu C, Li X.   +5 more
europepmc   +2 more sources

Long Noncoding RNA LINC01234 Functions as a Competing Endogenous RNA to Regulate CBFB Expression by Sponging miR-204-5p in Gastric Cancer

Clinical Cancer Research, 2018
Purpose: Long noncoding RNAs (lncRNAs) have emerged as important regulators in a variety of human diseases, including cancers. However, the overall biological roles and clinical significance of most lncRNAs in gastric carcinogenesis are not fully ...
Xin Chen, Zhenyao Chen, Shanxun Yu, Fengqi Nie, Shuai Yan, Pei Ma, Qinnan Chen, Chenchen Wei, Hangjiang Fu, Tianwei Xu, Shengnan Ren, Ming Sun, Zhaoxia Wang   +12 more
openalex   +2 more sources

Competing endogenous RNA (ceRNA) networks in Parkinson's disease: A systematic review. [PDF]

Front Cell Neurosci, 2023
Parkinson's disease (PD) is a distinctive clinical syndrome with several causes and clinical manifestations. Aside from an infectious cause, PD is a rapidly developing neurological disorder with a global rise in frequency.
Asadi MR, Abed S, Kouchakali G, Fattahi F, Sabaie H, Moslehian MS, Sharifi-Bonab M, Hussen BM, Taheri M, Ghafouri-Fard S, Rezazadeh M.   +10 more
europepmc   +2 more sources

Systematic analysis of lncRNA–miRNA–mRNA competing endogenous RNA network identifies four-lncRNA signature as a prognostic biomarker for breast cancer [PDF]

Journal of Translational Medicine, 2018
Increasing evidence has underscored the role of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) in the development and progression of tumors. Nevertheless, lncRNA biomarkers in lncRNA-related ceRNA network that can predict the
Chunni Fan, Lei Ma, Ning Liu
openalex   +2 more sources

Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia

Scientific Reports, 2021
Schizophrenia (SCZ) is a serious psychiatric condition with a 1% lifetime risk. SCZ is one of the top ten global causes of disabilities. Despite numerous attempts to understand the function of genetic factors in SCZ development, genetic components in SCZ
Hani Sabaie, Madiheh Mazaheri Moghaddam, Marziyeh Mazaheri Moghaddam, Noora Karim Ahangar, Mohammad Reza Asadi, Bashdar Mahmud Hussen, Mohammad Taheri, Maryam Rezazadeh   +7 more
doaj   +2 more sources