circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA [PDF]
eLife, 2023 Circular RNAs represent a class of endogenous RNAs that regulate gene expression and influence cell biological decisions with implications for the pathogenesis of several diseases.
Trine Line Hauge Okholm +13 more
doaj +7 more sources
Flavonoids Inhibit Cancer by Regulating the Competing Endogenous RNA Network
Frontiers in Oncology, 2022 Flavonoids are present in a wide range of plants. They have been used in the treatment of cancer, but the mechanism underlying this activity is unclear.
Chengshun Li +6 more
doaj +4 more sources
Modelling Competing Endogenous RNA Networks. [PDF]
PLoS ONE, 2013 MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs).
Carla Bosia +2 more
doaj +7 more sources
Competing endogenous RNA crosstalk at system level.
PLoS Computational Biology, 2019 microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression ...
Mattia Miotto +2 more
doaj +9 more sources
Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases [PDF]
International Journal of Molecular Sciences, 2020 Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex ...
Leticia Moreno-García +10 more
semanticscholar +5 more sources
Competing Endogenous RNA: The Key to Posttranscriptional Regulation [PDF]
The Scientific World Journal, 2014 Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA.
Rituparno Sen +4 more
doaj +4 more sources
H19 promotes osteogenic differentiation by functioning as a competing endogenous RNA
Journal of Orthopaedic Translation, 2016 Jin-fang Zhang +3 more
doaj +4 more sources
Long Noncoding Competing Endogenous RNA Networks in Pancreatic Cancer [PDF]
Frontiers in Oncology, 2021 Pancreatic cancer (PC) is a highly malignant disease characterized by insidious onset, rapid progress, and poor therapeutic effects. The molecular mechanisms associated with PC initiation and progression are largely insufficient, hampering the ...
Guangbing Xiong +10 more
doaj +3 more sources
Noncoding RNA-associated competing endogenous RNA networks in trastuzumab-induced cardiotoxicity [PDF]
Non-coding RNA ResearchTrastuzumab-induced cardiotoxicity (TIC) is a common and serious disease with abnormal cardiac function. Accumulating evidence has indicated certain non-coding RNAs (ncRNAs), functioning as competing endogenous RNAs (ceRNAs), impacting the progression of
Suifen Xie +8 more
doaj +2 more sources
Revealing Landscape of Competing Endogenous RNA Networks in Sepsis-Induced Cardiovascular Diseases [PDF]
Reviews in Cardiovascular Medicine, 2023 Cardiovascular dysfunction induced by sepsis is one of the most common phenotypes of cardiovascular diseases (CVDs), which is closely related to the high mortality of sepsis and is an urgent health problem to be solved worldwide. Unfortunately, the exact
Wei Xiong +4 more
doaj +2 more sources