Results 31 to 40 of about 365,100 (332)
Animals, 2022 Long non-coding RNAs (lncRNAs) are implicated in mammalian adipogenesis and obesity. However, their genome-wide distribution, expression profiles, and regulatory mechanisms during chicken adipogenesis remain rarely understood.
Weihua Tian +6 more
doaj +1 more source
Model-guided design of ligand-regulated RNAi for programmable control of gene expression [PDF]
, 2008 Progress in constructing biological networks will rely on the development of more advanced components that can be predictably modified to yield optimal system performance.
Chase L Beisel +4 more
core +5 more sources
Cell Death and Differentiation, 2019 The regulatory loop between long noncoding RNAs (lncRNAs) and microRNAs has a dynamic role in transcriptional and translational regulation, and is involved in cancer.
Min Wang +16 more
semanticscholar +1 more source
Cancer Cell International, 2020 Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu +5 more
doaj +1 more source
Mathematical Biosciences and Engineering, 2021 Heart failure (HF), a common disease in adults, accounts for significantly global morbidity and mortality. Due to population aging, therapeutic progression in acute cardiovascular events, the prevalence of HF is increasing, in spite of the efficacy of ...
Xudan Ma +5 more
doaj +1 more source
lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA. [PDF]
PLoS ONE, 2014 Long noncoding RNA (lncRNA) influences post-transcriptional regulation by interfering with the microRNA (miRNA) pathways, acting as competing endogenous RNA (ceRNA).
Shaoli Das +3 more
doaj +1 more source
KCNQ1OT1: An Oncogenic Long Noncoding RNA
Biomolecules, 2021 Long noncoding RNAs (lncRNAs) are transcripts greater than 200 nucleotides that do not code for proteins but regulate gene expression. Recent studies indicate that lncRNAs are involved in the modulation of biological functions in human disease.
Patrice Cagle +3 more
doaj +1 more source
Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response [PDF]
, 2017 Background: The mammalian endoplasmic reticulum (ER) continuously adapts to the cellular secretory load by the activation of an unfolded protein response (UPR).
Bulleid, Neil J. +4 more
core +2 more sources
Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases
International Journal of Molecular Sciences, 2020 Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex ...
Leticia Moreno-García +10 more
semanticscholar +1 more source
Expression profiling dataset of competing endogenous RNA in pre-eclampsia
Data in Brief, 2019 This data descriptor is an extended version of the methodologies which have been described in a related paper [1]; its purpose is to disseminate the raw data and analyzed data produced in this experiment. For more insight please see the research article,
Xiaopeng Hu +5 more
doaj +1 more source