Results 31 to 40 of about 351,891 (343)
Competing endogenous RNAs in lung cancer
Cancer Biology and Medicine, 2021 Competing endogenous RNAs (ceRNAs) containing microRNA response elements can competitively interact with microRNA via miRNA response elements, which can combine non-coding RNAs with protein-coding RNAs through complex ceRNA networks. CeRNAs include non-coding RNAs (long non-coding RNAs, circular RNAs, and transcribed pseudogenes) and protein-coding ...
Jianguo Feng, Liling Tang, Meilian Zhao
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Regulatory Potential of Competing Endogenous RNAs in Myotonic Dystrophies [PDF]
International Journal of Molecular Sciences, 2021 Non-coding RNAs (ncRNAs) have been reported to be implicated in cell fate determination and various human diseases. All ncRNA molecules are emerging as key regulators of diverse cellular processes; however, little is known about the regulatory interaction among these various classes of RNAs.
Edyta Koscianska +2 more
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Competing endogenous RNA network for esophageal cancer progression [PDF]
Annals of Translational Medicine, 2021 Esophageal cancer (ESCA) constitutes one of the most common cancers worldwide. The identification of potential biomarkers is important to improving the diagnostic accuracy and treatment efficiency for patients with ESCA. In this study, we aimed to identify biomarkers related to ESCA progression through a comprehensive analysis of long non-coding RNAs ...
Chen Saihua +9 more
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Competing endogenous RNA database [PDF]
Bioinformation, 2012 A given mRNA can be regulated by interactions with miRNAs and in turn the availability of these miRNAs can be regulated by their interactions with alternate mRNAs. The concept of regulation of a given mRNA by alternate mRNA (competing endogenous mRNA) by virtue of interactions with miRNAs through shared miRNA response elements is poised to become a ...
Subbaya Subramanian, Aaron L. Sarver
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BMC Gastroenterology, 2022 Background Patients with ulcerative colitis are at an increased risk of developing colorectal cancer with a prolonged disease course. Many studies have shown that alterations in the immune microenvironment play a key role in ulcerative colitis-associated
Shi Yin +8 more
doaj +1 more source
International Journal on Biological Sciences, 2021 The nuclear paraspeckle assembly transcript 1 (NEAT1) is a long non-coding RNA (lncRNA) that is upregulated in a variety of human cancer types. Increasing evidence has shown that the elevation of NEAT1 in cancer cells promotes cell growth, migration, and
Kun Li +4 more
semanticscholar +1 more source
PceRBase: a database of plant competing endogenous RNA [PDF]
Nucleic Acids Research, 2016 Competition for microRNA (miRNA) binding between RNA molecules has emerged as a novel mechanism for the regulation of eukaryotic gene expression. Competing endogenous RNA (ceRNA) can act as decoys for miRNA binding, thereby forming a ceRNA network by regulating the abundance of other RNA transcripts which share the same or similar microRNA response ...
Nicola Illing +6 more
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Integrated analysis of competing endogenous RNA in esophageal carcinoma [PDF]
Journal of Gastrointestinal Oncology, 2021 The Competing endogenous RNA (CeRNA) network plays important roles in the development and progression of multiple human cancers. Increasing attention has been paid to CeRNA in esophageal carcinoma (ESCA).We explored The Cancer Genome Atlas (TCGA) database and then analyzed the RNAs of 142 samples to obtain long non-coding RNAs (lncRNAs), micro RNAs ...
Nanzheng Chen +5 more
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Progress in Competing Endogenous RNA and Cancer [PDF]
Journal of Cancer Therapy, 2015 The competing endogenous RNA (ceRNA) hypothesis was introduced as a previously unrecognized gene regulatory layer. This is a recently discovered hypothesis about how mRNAs, pseudogene transcripts, long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) regulate post-transcriptional expression by sharing common microRNA response elements (MREs ...
Weiguo Huang, Ting Zhang
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BMC Plant Biology, 2021 Background Water deficit is an abiotic stress that retards plant growth and destabilizes crop production. Long non coding RNAs (lncRNAs) are a class of non-coding endogenous RNAs that participate in diverse cellular processes and stress responses in ...
Jiajia Chen, Yuqing Zhong, Xin Qi
semanticscholar +1 more source