Results 41 to 50 of about 365,100 (332)

Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Hepatocellular carcinoma (HCC) is a common and lethal type of cancer worldwide. The importance of non-coding RNAs such as long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs) have been recognized in the ...
Mohammad Donyavi, Sadra Salehi-Mazandarani, Parvaneh Nikpour   +2 more
doaj   +1 more source

CircPlekha7 plays an anti-fibrotic role in intrauterine adhesions by modulating endometrial stromal cell proliferation and apoptosis

The Journal of Reproduction and Development, 2020
Circular RNA (circRNA) plays a key role in the development and progression of several diseases; however, its role in intrauterine adhesions (IUAs) is not well understood.
Wei XIE, Min HE, Yuhuan LIU, Xiaowu HUANG, Dongmei SONG, Yu XIAO   +5 more
doaj   +1 more source

The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia

BMC Cancer, 2021
Background As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
Siyuan Zhang
doaj   +1 more source

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]

, 2010
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud, Farese, Robert V, Harris, Charles, Herker, Eva, Hernandez, Céline, Kaehlcke, Katrin, Ott, Melanie, Rosenberg, Arielle R   +7 more
core   +1 more source

A Key mRNA-miRNA-lncRNA Competing Endogenous RNA Triple Sub-network Linked to Diagnosis and Prognosis of Hepatocellular Carcinoma

Frontiers in Oncology, 2020
Growing evidence has illustrated critical roles of competing endogenous RNA (ceRNA) regulatory network in human cancers including hepatocellular carcinoma.
Junjie Zhang, Weiyang Lou
semanticscholar   +1 more source

Integral Analyses of Competing Endogenous RNA Mechanisms and DNA Methylation Reveal Regulatory Mechanisms in Osteosarcoma

Frontiers in Cell and Developmental Biology, 2021
Background: Osteosarcoma (OS) is the most common primary malignant bone tumour in children and adolescents, with rapid growth, frequent metastasis, and a poor prognosis, but its pathogenesis has not been fully elucidated. Exploring the pathogenesis of OS
Tingrui Wu, Bo Wei, Hao Lin, Boan Zhou, Tao Lin, Qianzheng Liu, Hongxun Sang, Huan Liu, Huan Liu, Wenhua Huang, Wenhua Huang, Wenhua Huang   +11 more
doaj   +1 more source

Long Non-Coding RNA- Associated Competing Endogenous RNA Axes in T-Cells in Multiple Sclerosis

Frontiers in Immunology, 2021
Multiple sclerosis (MS) is an immune-mediated demyelinating and degenerative disease with unknown etiology. Inappropriate response of T-cells to myelin antigens has an essential role in the pathophysiology of MS.
Hani Sabaie, Hani Sabaie, Zoha Salkhordeh, Mohammad Reza Asadi, Soudeh Ghafouri-Fard, Nazanin Amirinejad, Mahla Askarinejad Behzadi, Bashdar Mahmud Hussen, Mohammad Taheri, Mohammad Taheri, Maryam Rezazadeh, Maryam Rezazadeh   +11 more
doaj   +1 more source

A Signature of Five Long Non-Coding RNAs for Predicting the Prognosis of Alzheimer's Disease Based on Competing Endogenous RNA Networks

Frontiers in Aging Neuroscience, 2021
Long non-coding RNAs (lncRNAs) play important roles in the pathogenesis of Alzheimer's disease (AD). However, the functions and regulatory mechanisms of lncRNA are largely unclear. Herein, we obtained 3,158 lncRNAs by microarray re-annotation.
Huaying Cai, Jin Xing, Jin Luya, Linhui Ni, S. Di, Xianjun Ding   +5 more
semanticscholar   +1 more source

Differently Expressed Circular RNAs in Lacrimal Sacs From Patients With Chronic Dacryocystitis

Frontiers in Genetics, 2022
This study was designed to identify differently expressed circular RNAs (circRNAs) and investigate their potential roles in lacrimal sacs from patients with chronic dacryocystitis.
Yue Li, Yue Li, Xueru Liu, Xueru Liu, Wenyue Zhang, Wenyue Zhang, Xuefei Song, Xuefei Song, Leilei Zhang, Leilei Zhang, Caiwen Xiao, Caiwen Xiao   +11 more
doaj   +1 more source

Probing the limits to microRNA-mediated control of gene expression [PDF]

, 2016
According to the `ceRNA hypothesis', microRNAs (miRNAs) may act as mediators of an effective positive interaction between long coding or non-coding RNA molecules, carrying significant potential implications for a variety of biological processes.
De Martino, Andrea, Figliuzzi, Matteo, Marinari, Enzo, Martirosyan, Araks   +3 more
core   +6 more sources