Results 41 to 50 of about 351,891 (343)

Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs

open access: yesRespiratory Research, 2020
Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao   +5 more
doaj   +1 more source

The emerging roles of non-coding competing endogenous RNA in hepatocellular carcinoma

open access: yesCancer Cell International, 2020
Accumulating evidence has emerged revealing that noncoding RNAs (ncRNAs) play essential roles in the occurrence and development of hepatocellular carcinoma (HCC). However, the complicated regulatory interactions among various ncRNAs in the development of
Gang Xu   +6 more
doaj   +1 more source

A Novel Immune-Related Competing Endogenous RNA Network Predicts Prognosis of Acute Myeloid Leukemia

open access: yesFrontiers in Oncology, 2020
BackgroundAcute myeloid leukemia (AML) is a genetically, biologically and clinically heterogeneous hematopoietic malignancy that is highly dependent on the bone marrow (BM) microenvironment.
Shujuan Wang   +7 more
doaj   +1 more source

MiR-96 induced non-small-cell lung cancer progression through competing endogenous RNA network and affecting EGFR signaling pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): Non-small cell lung cancer (NSCLC) has become a serious global health problem in the 21st century, and tumor proliferation and metastasis are the leading causes of death in patients  with lung cancer.
Hao Ding   +5 more
doaj   +1 more source

Roles of competing endogenous RNAs in gastric cancer [PDF]

open access: yesBriefings in Functional Genomics, 2015
Long noncoding RNA (lncRNA) is >200 nucleotides long and lacks coding ability. LncRNA was regarded as transcript noise, until emerging results showed its roles in development, homeostasis and carcinogenesis. LncRNAs containing microRNA (miRNA) response elements could compete with the miRNA target gene and regulate its expression through decreasing free
Jing-Yuan Fang   +3 more
openaire   +3 more sources

Comprehensive circRNA-microRNA-mRNA network analysis revealed the novel regulatory mechanism of Trichosporon asahii infection

open access: yesMilitary Medical Research, 2021
Background Invasive Trichosporon asahii (T. asahii) infection frequently occurs with a high mortality in immunodeficient hosts, but the pathogenesis of T. asahii infection remains elusive.
Ming-Wang Zhang   +6 more
doaj   +1 more source

The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA [PDF]

open access: yes, 2016
Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells.
Bozzoni, Irene   +8 more
core   +2 more sources

Comparative Transcriptome Analysis Reveals Regulatory Mechanism of Long Non-Coding RNAs during Abdominal Preadipocyte Adipogenic Differentiation in Chickens

open access: yesAnimals, 2022
Long non-coding RNAs (lncRNAs) are implicated in mammalian adipogenesis and obesity. However, their genome-wide distribution, expression profiles, and regulatory mechanisms during chicken adipogenesis remain rarely understood.
Weihua Tian   +6 more
doaj   +1 more source

Analyzing the lncRNA, miRNA, and mRNA-associated ceRNA networks to reveal potential prognostic biomarkers for glioblastoma multiforme

open access: yesCancer Cell International, 2020
Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu   +5 more
doaj   +1 more source

Establishment and analysis of the lncRNA-miRNA-mRNA network based on competitive endogenous RNA identifies functional genes in heart failure

open access: yesMathematical Biosciences and Engineering, 2021
Heart failure (HF), a common disease in adults, accounts for significantly global morbidity and mortality. Due to population aging, therapeutic progression in acute cardiovascular events, the prevalence of HF is increasing, in spite of the efficacy of ...
Xudan Ma   +5 more
doaj   +1 more source

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