Results 251 to 260 of about 83,602 (280)

Competing endogenous RNA network of endometrial carcinoma: A comprehensive analysis

Journal of Cellular Biochemistry, 2019
AbstractCompeting endogenous RNA (ceRNA) network is dysregulated in the initiation and progression of tumors. In the present study, we explored the regulatory mechanism of ceRNA in endometrial carcinoma (EC) and the potential key molecules with potential value in the diagnosis, treatment, and prognosis of EC.
Wenjun Cheng, Nie Sipei, Jinhui Liu
exaly   +3 more sources

A Method for Constructing an Integrative Network of Competing Endogenous RNAs

2021
Since the new gene regulation involving competing endogenous RNA (ceRNA) interactions targeted by common microRNAs (miRNAs) was found, several computational methods have been proposed to derive ceRNA networks. However, most of the ceRNA networks are restricted to represent either miRNA-target RNA interactions or lncRNA-miRNA-mRNA interactions. From the
Seokwoo Lee, Wook Lee, Shulei Ren, Kyungsook Han   +3 more
openaire   +1 more source

Competing endogenous RNAs: a target-centric view of small RNA regulation in bacteria [PDF]

Nature Reviews Microbiology, 2016
International audienceMany bacterial regulatory small RNAs (sRNAs) have several mRNA targets, which places them at the centre of regulatory networks that help bacteria to adapt to environmental changes.
Nara Figueroa-Bossi, Lionello Bossi
exaly   +2 more sources

Circular RNA expression profile and competing endogenous RNA regulatory network in preeclampsia

Placenta, 2022
Preeclampsia (PE) is a pregnancy specific disorder which is significantly associated with maternal and neonatal morbidity and mortality. This study aimed to explore the potential role of circRNAs in PE.The mRNA, miRNA, and circRNA expression profiles of PE were downloaded from GEO database.
Yuan, Yuan, Yunhui, Gong, Lu, Zhong, Xiaohong, Ding, Zhiying, Yang, Xiao, Su, Mi, Chen, Fei, Zhang, Li, Yang   +8 more
openaire   +2 more sources

Differentially expressed circular RNAs and the competing endogenous RNA network associated with preeclampsia

Placenta, 2021
Circular RNAs (circRNAs) are non-coding RNAs that are implicated in preeclampsia (PE) pathogenesis; however, their expression and functions in PE remain unclear. In this study, we aimed to investigate the expression of circRNAs in PE and construct a competing endogenous RNA (ceRNA) network, and analyze the associated pathways in PE pathogenesis.We ...
Bo, Ma, Huanqiang, Zhao, Lili, Gong, Xirong, Xiao, Qiongjie, Zhou, Huiqing, Lu, Yutong, Cui, Huangfang, Xu, Suwen, Wu, Yao, Tang, Yunzhen, Ye, Weirong, Gu, Xiaotian, Li   +12 more
openaire   +2 more sources

Noncoding RNA-Associated Competing Endogenous RNA Networks in Doxorubicin-Induced Cardiotoxicity

DNA and Cell Biology, 2022
Accumulating evidence has indicated that noncoding RNAs (ncRNAs) are involved in doxorubicin-induced cardiotoxicity (DIC). However, the ncRNA-associated competing endogenous RNA (ceRNA)-mediated regulatory mechanisms in DIC remain unclear. In this study, we aimed to systematically investigate the alterations in expression levels of long noncoding RNA ...
Zijun Xiao, Shanshan Wei, Jie Huang, Jiaqin Liu, Jian Liu, Bikui Zhang, Wenqun Li   +6 more
openaire   +2 more sources

Identification of Long Non-Coding RNA-Associated Competing Endogenous RNA Network in the Differentiation of Chicken Preadipocytes [PDF]

Genes, 2019
Emerging evidence indicates that long noncoding RNAs (lncRNAs) play important roles in the regulation of cell differentiation by acting as competing endogenous RNA (ceRNA).
Kaizhou Xie, , Jinyu Wang
exaly   +2 more sources

A New Network-Based Tool to Analyse Competing Endogenous RNAs

2020
Interactions between microRNA targets are defined as competing endogenous RNAs. After discovery of the repressive activity of microRNAs with different mechanisms, various experimental or computational approaches have been developed to understand the relationships among their targets.
Selcen Ari Yuka, Alper Yilmaz 0003
openaire   +2 more sources

Identification of competing endogenous RNA network in laryngeal squamous cell carcinoma

Oral Diseases, 2021
AbstractObjectiveThis study was conducted to investigate key long noncoding RNAs (lncRNAs) involved in competitive endogenous RNA (ceRNA) network associated with laryngeal squamous cell carcinoma (LSCC).Materials and MethodsThree mRNA datasets, two miRNA datasets, and one lncRNA dataset of LSCC were downloaded from GEO database.
Xiao‐Feng Cui, Si‐Lin Zhang, Wei‐Ping Wang, Xiao‐Wu Huang, Xiang‐Jun Chen   +4 more
openaire   +2 more sources

Modeling competing endogenous RNA regulatory networks in glioblastoma multiforme

2013 IEEE International Conference on Bioinformatics and Biomedicine, 2013
Recent studies postulated that genes harboring identical microRNA (miRNA) binding sites can crosstalk by competing for a limited pool of the binding miRNAs (the miRNA program), named as the regulation of competing endogenous RNAs (ceRNAs). Incorporating recent biological evidence that ceRNA regulation depends on miRNA program expression levels, we ...
Yu-Chiao Chiu, Eric Y. Chuang, Tzu-Hung Hsiao, Yidong Chen 0002   +3 more
openaire   +1 more source