Results 261 to 270 of about 125,024 (282)

Circular RNA expression profile and competing endogenous RNA regulatory network in preeclampsia

Placenta, 2022
Preeclampsia (PE) is a pregnancy specific disorder which is significantly associated with maternal and neonatal morbidity and mortality. This study aimed to explore the potential role of circRNAs in PE.The mRNA, miRNA, and circRNA expression profiles of PE were downloaded from GEO database.
Yuan, Yuan, Yunhui, Gong, Lu, Zhong, Xiaohong, Ding, Zhiying, Yang, Xiao, Su, Mi, Chen, Fei, Zhang, Li, Yang   +8 more
openaire   +2 more sources

Differentially expressed circular RNAs and the competing endogenous RNA network associated with preeclampsia

Placenta, 2021
Circular RNAs (circRNAs) are non-coding RNAs that are implicated in preeclampsia (PE) pathogenesis; however, their expression and functions in PE remain unclear. In this study, we aimed to investigate the expression of circRNAs in PE and construct a competing endogenous RNA (ceRNA) network, and analyze the associated pathways in PE pathogenesis.We ...
Bo, Ma, Huanqiang, Zhao, Lili, Gong, Xirong, Xiao, Qiongjie, Zhou, Huiqing, Lu, Yutong, Cui, Huangfang, Xu, Suwen, Wu, Yao, Tang, Yunzhen, Ye, Weirong, Gu, Xiaotian, Li   +12 more
openaire   +2 more sources

Identification of competing endogenous RNA network in laryngeal squamous cell carcinoma

Oral Diseases, 2021
AbstractObjectiveThis study was conducted to investigate key long noncoding RNAs (lncRNAs) involved in competitive endogenous RNA (ceRNA) network associated with laryngeal squamous cell carcinoma (LSCC).Materials and MethodsThree mRNA datasets, two miRNA datasets, and one lncRNA dataset of LSCC were downloaded from GEO database.
Xiao‐Feng Cui, Si‐Lin Zhang, Wei‐Ping Wang, Xiao‐Wu Huang, Xiang‐Jun Chen   +4 more
openaire   +2 more sources

Integrated analysis of long noncoding RNA‐associated competing endogenous RNA network in periodontitis

Journal of Periodontal Research, 2018
Background and ObjectivesLong noncoding RNAs (lncRNAs) play critical and complex roles in regulating various biological processes of periodontitis. This bioinformatic study aims to construct a putative competing endogenous RNA (ceRNA) network by integrating lncRNA, miRNA and mRNA expression, based on high‐throughput RNA sequencing and microarray data ...
S. Li, X. Liu, H. Li, H. Pan, A. Acharya, Y. Deng, Y. Yu, R. Haak, J. Schmidt, G. Schmalz, D. Ziebolz   +10 more
openaire   +4 more sources

Modeling competing endogenous RNA regulatory networks in glioblastoma multiforme

2013 IEEE International Conference on Bioinformatics and Biomedicine, 2013
Recent studies postulated that genes harboring identical microRNA (miRNA) binding sites can crosstalk by competing for a limited pool of the binding miRNAs (the miRNA program), named as the regulation of competing endogenous RNAs (ceRNAs). Incorporating recent biological evidence that ceRNA regulation depends on miRNA program expression levels, we ...
Yu-Chiao Chiu, Eric Y. Chuang, Tzu-Hung Hsiao, Yidong Chen   +3 more
openaire   +1 more source

Comprehensive analysis of long noncoding RNA-associated competing endogenous RNA network in cholangiocarcinoma

Biochemical and Biophysical Research Communications, 2018
Long non-coding RNAs (lncRNAs) can interact with microRNAs (miRNAs) as a competing endogenous RNA (ceRNA) to regulate the expression of target genes, which can largely influence on tumorigenesis and tumor progression. However, the role of lncRNA-mediated ceRNAs in cholangiocarcinoma (CCA) remains unknown.
Wei, Song, Dong-Liu, Miao, Lei, Chen
openaire   +2 more sources

Competing endogenous RNA networks in cervical cancer: function, mechanism and perspective

Journal of Drug Targeting, 2019
In the past several years, competing endogenous RNAs (ceRNAs) have emerged as a potential class of post-transcriptional regulators that alter gene expression through a microRNA (miRNA)-mediated mechanism. An increasing number of studies have found that ceRNAs play important roles in tumorigenesis.
Hui, Du, Ying, Chen
openaire   +2 more sources

Competing endogenous RNA network in pulmonary arterial hypertension

International Journal of Cardiology, 2014
Kai, Ma, Qian, Zhao, Shoujun, Li
openaire   +2 more sources

Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation

Emerging Microbes and Infections, 2020
Xi ZHANG, Hin Chu, Lei Wen
exaly  

An integrated analysis of the competing endogenous RNA network and co-expression network revealed seven hub long non-coding RNAs in osteoarthritis

Bone and Joint Research, 2020
Haitao Chen
exaly