Whole transcriptome sequencing identifies a competitive endogenous RNA network that regulates the immunity of bladder cancer [PDF]
HeliyonKangli Deng
exaly +2 more sources
Related searches:
Computational prediction of competitive endogenous RNA
2015 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2015MicroRNAs (miRNAs) play an important role in the post-transcriptional regulation of gene expression by pairing target messenger RNAs (mRNAs). As the abnormal expression of miRNAs has been implicated in various diseases, there has been many studies on regulating the expression level of miRNA, including “miRNA sponges.” miRNA sponges, which are ...
Seunghyun Park 0001 +3 more
openaire +1 more source
Mimicry, deception and competition: The life of competing endogenous RNAs
WIREs RNA, 2019Since their discovery, small regulatory RNAs (sRNAs) were thought to be regulated exclusively at the transcriptional level. However, accumulating data from recent reports indicate that posttranscriptional signals can also modulate the function and stability of sRNAs.
Marc P, Grüll, Eric, Massé
openaire +2 more sources
Predicting protective gene biomarker of acute coronary syndrome by the circRNA-associated competitive endogenous RNA regulatory network [PDF]
Frontiers in Genetics, 2022 Hengliang Zhang +2 more
exaly +2 more sources
Sp1 is a competitive endogenous RNA of Klf4 during odontoblast differentiation
The International Journal of Biochemistry & Cell Biology, 2017Our previous studies have demonstrated that KLF4 is a critical transcription factor that promotes the odontoblastic differentiation of dental papilla cells. Klf4 mRNA was found to be regulated by multiple microRNAs (miRNAs). Competitive endogenous RNAs (ceRNAs) are a group of transcripts post-transcriptionally regulating each other by competing for ...
Jie, Zhang +7 more
openaire +2 more sources
Construction of a Competitive Endogenous RNA Network Related to Exosomes in Diabetic Retinopathy
Combinatorial Chemistry & High Throughput Screening, 2023Background: The competing endogenous RNA (ceRNA) network plays an important role in the occurrence and development of a variety of diseases. This study aimed to construct a ceRNA network related to exosomes in diabetic retinopathy (DR). Methods: We explored the Gene Expression Omnibus (GEO) database and then analyzed the RNAs of samples to obtain ...
Tong, Wang +6 more
openaire +2 more sources
Competitive Endogenous RNAs Participate in Benzene Hematotoxicity by Promoting Ferroptosis
SSRN Electronic Journal, 2021Background: Benzene exposure leads to hematotoxicity, but we still lack sensitive biomarkers for its monitoring and prevention owing to the complex mechanisms. We previously constructed a competitive endogenous RNA(ceRNA) regulatory network (Lnc-TC-miR-142-5p-CUL4B), which may be potential biomarkers for benzene hematotoxicity, and further explored the
Jing Ren +5 more
openaire +1 more source
Analysis of Competitive Endogenous RNA Regulatory Network of Exosomal Breast Cancer Based on exoRBase [PDF]
Evolutionary Bioinformatics, 2022 Zhu K, Wang Q, Wang L.
exaly +2 more sources
Accumulating evidence shows that circular RNA (circRNA) is an important regulator of many diseases, especially cancer. Gastric cancer (GC) is a malignant tumor of the digestive system. The regulatory role and potential mechanism of circRNAs in GC remain unknown.
Tong Han +4 more
openaire +2 more sources
Pseudogenes as Competitive Endogenous RNAs: Target Prediction and Validation
2014Pseudogenes may regulate expression of their parental genes as well as other protein-coding genes through various mechanisms. One such mechanism is the ability to act as competitive endogenous RNA (ceRNA) and participate in microRNA-mediated cross-regulation.
Karreth, Florian A. +3 more
openaire +4 more sources