Results 221 to 230 of about 56,767 (239)
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Cancer Gene Therapy, 2021
Accumulating evidence shows that circular RNA (circRNA) is an important regulator of many diseases, especially cancer. Gastric cancer (GC) is a malignant tumor of the digestive system. The regulatory role and potential mechanism of circRNAs in GC remain unknown.
Tong Han +4 more
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Accumulating evidence shows that circular RNA (circRNA) is an important regulator of many diseases, especially cancer. Gastric cancer (GC) is a malignant tumor of the digestive system. The regulatory role and potential mechanism of circRNAs in GC remain unknown.
Tong Han +4 more
openaire +2 more sources
The BRAF Pseudogene Is a Proto-Oncogenic Competitive Endogenous RNA
Blood, 2014Abstract Non-coding RNAs have long been viewed as non-functional genomic relicts of evolution, but recetn findings have implicated their importance in physiology and disease. Recently, in vitro experiments demonstrated that the pseudogenes of PTEN and KRAS operate as natural miRNA decoys (competitive endogenous RNAs or ceRNAs) that ...
Florian Karreth +5 more
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Competitive endogenous RNA network: potential implication for systemic lupus erythematosus
Expert Opinion on Therapeutic Targets, 2017Competitive endogenous RNA (ceRNA) hypothesis proposes that RNA transcripts, both coding and non-coding, crosstalk with and coregulate each other using microRNA response elements (MREs). CeRNA analysis tremendously expands functional information of coding and non-coding RNAs.
Hai-Feng Pan +2 more
exaly +3 more sources
Clinical and Experimental Medicine, 2020
To investigate lncRNAs acting as competing endogenous RNAs (ceRNAs) involved in oncogenesis and progression of HCC. Different expressed lncRNAs, microRNAs, and mRNAs (DElncRNAs, DEmiRNAs, DEmRNAs), downloaded from The Cancer Genome Atlas (TCGA) database, were identified by edgeR package.
Lili Qu +8 more
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To investigate lncRNAs acting as competing endogenous RNAs (ceRNAs) involved in oncogenesis and progression of HCC. Different expressed lncRNAs, microRNAs, and mRNAs (DElncRNAs, DEmiRNAs, DEmRNAs), downloaded from The Cancer Genome Atlas (TCGA) database, were identified by edgeR package.
Lili Qu +8 more
openaire +2 more sources
Combinatorial Chemistry & High Throughput Screening, 2020
Background: Neonatal sepsis is a serious and difficult-to-diagnose systemic infectious disease occurring during the neonatal period. Objective: This study aimed to identify potential biomarkers of neonatal sepsis and explore its underlying mechanisms.
Ling, Liu +3 more
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Background: Neonatal sepsis is a serious and difficult-to-diagnose systemic infectious disease occurring during the neonatal period. Objective: This study aimed to identify potential biomarkers of neonatal sepsis and explore its underlying mechanisms.
Ling, Liu +3 more
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Immune-Related Hub Genes and the Competitive Endogenous RNA Network in Alzheimer’s Disease
Journal of Alzheimer’s Disease, 2020Background: The pathogenesis of Alzheimer’s disease (AD) involves various immune-related phenomena; however, the mechanisms underlying these immune phenomena and the potential hub genes involved therein are unclear.
Hui, Xu, Jianping, Jia
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Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020
Long noncoding RNAs (lncRNAs) have gain increasing attention in lung adenocarcinoma. In this study, we aimed at constructing and analyzing the lncRNAs and the related proteins based competitive endogenous RNA (ceRNA) network.RNA expression data of lung adenocarcinoma were extracted from the TCGA database.
Chang, Gu +6 more
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Long noncoding RNAs (lncRNAs) have gain increasing attention in lung adenocarcinoma. In this study, we aimed at constructing and analyzing the lncRNAs and the related proteins based competitive endogenous RNA (ceRNA) network.RNA expression data of lung adenocarcinoma were extracted from the TCGA database.
Chang, Gu +6 more
openaire +2 more sources
2019
MicroRNAs (miRNAs) are fine-tuners of gene expression and contribute to the regulation of most, if not all, biological processes in eukaryotes by targeting both coding and noncoding RNAs. Typically, miRNAs repress numerous target transcripts and most target RNAs harbor binding sites for multiple miRNA families. It was recently proposed that transcripts
openaire +2 more sources
MicroRNAs (miRNAs) are fine-tuners of gene expression and contribute to the regulation of most, if not all, biological processes in eukaryotes by targeting both coding and noncoding RNAs. Typically, miRNAs repress numerous target transcripts and most target RNAs harbor binding sites for multiple miRNA families. It was recently proposed that transcripts
openaire +2 more sources
Computational Epigenetics: The Competitive Endogenous RNAs Network Analysis
2023openaire +1 more source