Results 121 to 130 of about 341,437 (266)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Molecular determinants of STEC-HUS: from complement activation to microvascular thrombosis. [PDF]

Front Immunol
Santarsiero D, Galbusera M, Gastoldi S, Bresin E, Piras R, Alberti M, Vivarelli M, Prandini S, Conti S, Zotta F, Schubart A, Benigni A, Remuzzi G, Noris M, Aiello S.   +14 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Yersinia enterocolitica O:3 Outer Membrane Vesicles as a Platform for Complement Activation. [PDF]

J Extracell Vesicles
Battaglino C, Bodnaruk I, Czyszczoń P, Skurnik M, Filip-Psurska B, Jarych D, Maciejewska A, Gadzinowski M, Malik K, Potocka I, Migdał P, Kruszakin R, Cedzyński M, Kasperkiewicz K, Lukasiewicz J, Świerzko AS.   +15 more
europepmc   +1 more source

Complement Activation in Pemphigus

Journal of Investigative Dermatology, 1980
openaire   +2 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Complement activation in secondary thrombotic microangiopathies. [PDF]

Nephrol Dial Transplant
Morelle J, Caravaca-Fontan F, Fakhouri F, Frangou E, Bruchfeld A, Floege J, Mirioglu S, Moran SM, Steiger S, Stevens KI, Teng OYK, Aydin S, Java A, Timmermans SAMEG, Kronbichler A.   +14 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Engineering Liposomes and Polymer Conjugates: A Platform for Mechanistic Complement Activation Studies and Controlled Release Applications. [PDF]

ACS Appl Mater Interfaces
Hoecherl K, Konrad J, Reiner C, Streif S, Spitzenberg C, Sommer C, Pauly D, Breunig M, Baeumner AJ.   +8 more
europepmc   +1 more source

Compliments from complement: a fourth pathway of complement activation? [PDF]

Nephrology Dialysis Transplantation, 2006
Mohamed R, Daha, Cees, van Kooten, Anja, Roos   +2 more
openaire   +2 more sources