Results 201 to 210 of about 325,802 (246)

Current Understanding of the Pathogenesis of ANCA-Associated Vasculitis and Novel Treatment Options Targeting Complement Activation. [PDF]

Life (Basel)
Drouzas K, Kalogeropoulos P, Liapis G, Lionaki S.   +3 more
europepmc   +1 more source

Complement activation at the interface between adipocytes and cancer cells drives tumor progression. [PDF]

JCI Insight
Valdivia A, Isac AM, Cardenas H, Zhao G, Zhang Y, Huang H, Wei JJ, Cuello-Fredes M, Kato S, Gómez-Valenzuela F, Gourronc F, Klingelhutz A, Matei D.   +12 more
europepmc   +1 more source

Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Oechtering J, Schaedelin SA, Stein K, Maleska Maceski A, Melie-Garcia L, Benkert P, Cagol A, Leber S, Galbusera R, Ruberte E, Hu W, Qureshi F, Orleth A, Demuth L, Willemse E, Heijnen I, Regeniter A, Derfuss TJ, Fischer-Barnicol B, Achtnichts L, Mueller S, Hoepner R, Lalive PH, Bridel C, D'Souza M, Pot C, Du Pasquier RA, Gobbi C, Zecca C, Wiendl H, Lieb JM, Lamers C, Kappos L, Trendelenburg M, Leppert D, Granziera C, Kuhle J, Lünemann JD, and the Swiss MS Cohort Study.   +38 more
europepmc   +1 more source

Hypertension in Living Kidney Donors Has No Effect on Complement Activation and Fibrosis.

Kidney Blood Press Res
Wagner N, Angeloni M, Ferrazzi F, Müller-Deile J, Büttner-Herold M, Amann K, Daniel C, Vonbrunn E.   +7 more
europepmc   +1 more source

Complement activation by IgM autoantibodies linked to immune-mediated neuropathies depends on C2. [PDF]

Eur J Neurol
Budding K, Dijkxhoorn K, de Zeeuw E, Bloemenkamp LM, van der Pol WL, Notermans NC, Minnema MC, Leusen JHW, Hack CE, Van de Walle I.   +9 more
europepmc   +1 more source

Complement activation and vascular complications after pediatric allogeneic hematopoietic stem cell transplantation. [PDF]

Sci Rep
Leimi L, Vettenranta K, Meri S.
europepmc   +1 more source

Oxidative Stress and Complement Activation in Aqueous Cells and Vitreous from Patient with Vitreoretinal Diseases: Comparison Between Diabetic ERM and PDR. [PDF]

Antioxidants (Basel)
Dinice L, Cosimi P, Esposito G, Scarinci F, Cacciamani A, Cafiero C, Placentino L, Ripandelli G, Micera A.   +8 more
europepmc   +1 more source

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Bispecific Complement Engagers for Targeted Complement Activation

The Journal of Immunology, 2023
Abstract Activation of the complement system represents an important effector mechanism of endogenous and therapeutic Abs. However, efficient complement activation is restricted to a subset of Abs due to the requirement of multivalent interactions between the Ab Fc regions and the C1 complex.
Dennis V Pedersen, Heidi Gytz, Mikael B L Winkler, Alessandra Zarantonello, Niklas Baumann, Annette G Hansen, Steffen Thiel, Gregers R Andersen, Thomas Valerius, Nick S Laursen   +9 more
openaire   +3 more sources