Results 201 to 210 of about 638,552 (336)

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Occurrence of Complement Activation Specific Neonantigens on Peripheral Blood Leukocytes [PDF]

, 1978
John S. Sundsmo, William P. Kolb, John G. Curd, Hans J. Müller‐Eberhard   +3 more
openalex   +1 more source

Role of local complement activation in kidney fibrosis and repair. [PDF]

J Clin Invest
Portilla D, Sabapathy V, Chauss D.
europepmc   +1 more source

The Role of C1q in the Internal Activation of the First Component of Complement (C1): Studies in Serum of a Selective C1q-Deficient Patient [PDF]

, 1978
Michael Loos, Rolf Thesen, A.I. van Berkel   +2 more
openalex   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Complement Activation in BK Polyoma Virus Nephropathy: What's the Story? [PDF]

Kidney Int Rep
Stokes MB.
europepmc   +1 more source

THE GROUP B STREPTOCOCCUS (GBS) AND COMPLEMENT (C) ACTIVATION: CLINICAL AND LABORATORY CORRELATES WITH GRAM NEGATIVE SEPSIS [PDF]

, 1977
Lawrence J. Fenton, Robert C. Strunk, Grant Morrow   +2 more
openalex   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Complement activation by the artificial surface of cardiopulmonary bypass is a persistent clinical problem. [PDF]

Sci Rep
Bierer JD, Stanzel R, Henderson M, El-Rabahi T, Sapp J, Andreou P, Marshall JS, Conrad D, Horne D.   +8 more
europepmc   +1 more source

Activation of Human Complement by Human Lymphoid Cells Sensitized with Histocompatibility Alloantisera

, 1973
Soldano Ferrone, Neil R. Cooper, M. A. Pellegrino, R. Reisfeld   +3 more
openalex   +1 more source