Results 221 to 230 of about 4,342,004 (341)

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Cell, 2016
Hansen Lui, Jiasheng Zhang, S. Makinson, Michelle K. Cahill, Kevin W. Kelley, Hsin-Yi Huang, Yulei Shang, M. Oldham, L. H. Martens, Fuying Gao, G. Coppola, S. Sloan, Christine L. Hsieh, Charles C. Kim, E. Bigio, S. Weintraub, M. Mesulam, R. Rademakers, I. Mackenzie, W. Seeley, A. Karydas, B. Miller, B. Borroni, R. Ghidoni, Robert V Farese, J. Paz, B. Barres, E. Huang   +27 more
semanticscholar   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang, Jianli Zhao, Xue Zhao, Xiaowei Hu, Zichun Xiao, Jie Wu, Xiaowen Li, Jing Xu, Yu‐Jing Li   +8 more
wiley   +1 more source

IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy. [PDF]

Neurol Neuroimmunol Neuroinflamm
Krijgsman D, Dijkxhoorn K, de Zeeuw E, Bloemenkamp LM, Bos JW, van Eijk RPA, Van de Walle I, Huizinga R, Jacobs BC, Leusen JHW, Pasterkamp RJ, Hack CE, Budding K, van der Pol WL.   +13 more
europepmc   +1 more source

The response to lipopolysaccharide of mouse spleen lymphocytes fractionated on the basis of surface immunoglobulin and complement receptor using fluorescence-activated cell sorting and rosetting techniques.

, 1979
David L. Brandon, Andrew J. Edwards, R. M. E. Parkhouse   +2 more
openalex  

Local complement activation in aqueous humor in patients with age-related macular degeneration

Eye, 2017
Michael Kirschfink, Tina Schick, Marlin Steinhauer, A. Aslanidis, L. Altay, Marcus Karlstetter, T. Langmann, Sascha Fauser   +7 more
semanticscholar   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Complement activation assessed by C3bc and C5b-9 terminal complex as diagnostic biomarkers for deep vein thrombosis. [PDF]

PLoS One
Wikan VE, Øverli Ø, Ueland T, Mollnes TE, Brækkan SK, Michelsen AE, Yeganeh GJ, Hansen JB, Brodin EE.   +8 more
europepmc   +1 more source

Complement activation by IgG subclasses is governed by their ability to oligomerize upon antigen binding [PDF]

Nikolaus Frischauf, Jürgen Strasser, Ellen G. F. Borg, Aran F. Labrijn, Frank J. Beurskens, Johannes Preiner   +5 more
openalex   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

House Dust Mite Nebulization Drives Alarmin and Complement Activation in a Murine Tracheal Air-Liquid Interface Culture System. [PDF]

Cells
Ahmad JH, Einwohlt P, Ohms M, Wilflingseder D, Köhl J.   +4 more
europepmc   +1 more source