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Complement Activation During Hemodialysis
Journal of Biomaterials Applications, 1989Hemodialysis, as other extracorporeal circulation treatments, determines activation of the complement system. In this paper molecular mechanism of complement activation by different hemodialysis membranes are reviewed as well as the biological consequences and clinical relevance of the ac tivation.
A. Agostoni, M. Gardinali, A. Cantaluppi
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Complement Activation and Pregnancy Failure
Clinical Reviews in Allergy & Immunology, 2009Pregnancy represents a physiologic condition where maternal immune system tolerates the semi-allogenic fetus. The fetal tissues are directly exposed to the maternal blood with potential attacks from maternal immune system, including the activation of complement cascade. Small amounts, of both early and late components, of complement are physiologically
TINCANI, Angela +5 more
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Complement Activation and Cardiovascular Disease
Hormone and Metabolic Research, 2008The mechanisms by which tissue injury after acute myocardial infarction occurs have not been fully elucidated, but considerable evidence suggests that activation of complement plays an important role in the pathophysiology. Reperfusion of the ischemic myocardium is strictly necessary to rescue the exposed tissue from eventual death.
Bjerre, Mette +2 more
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Complement activation in hypercholesterolemia.
Nutrition, metabolism, and cardiovascular diseases : NMCD, 2000Inflammatory and lipid factors share an important role in atherosclerosis. This study evaluates their relations in dyslipidemic subjects.We compared the complement system (serum hemolytic activity CH50, C3 and C4 fractions and terminal complex sC5b-9) in 30 hypercholesterolemic patients with elevated cholesterol and decreased HDL-cholesterol levels, 30
PASQUI A. L. +5 more
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Activation of complement by trypanosomes
Experientia, 1977Factors exhibiting anti-complementary activity released from trypanosomes after incubation at 20 degrees C were described. The active material was shown to consume the first component of bovine complement. While the anti-complementary factor(s) from T. lewisi could activate bovine, human and guinea pig complement, the factor(s) from T.
K, Nielsen, J, Sheppard
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Ficolins in complement activation
Molecular Immunology, 2013Ficolins are a group of multimeric lectins made up of single subunits each of which is composed of a collagen-like domain and a fibrinogen-like domain. Most of the ficolins identified to date bind to acetylated compounds such as N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc).
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Haemolytic complement activity in infants
Zeitschrift f�r Kinderheilkunde, 1973In 111 sera of sick and 30 sera of healthy infants aged 14 days to 12 months hemolytic activity of complement was estimated photometrically as described by Kabat, titres being expressed in 50% hemolytic units (C′H50).
M, Büsse, J, Ströder
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Assays for Complement Activation
Clinics in Laboratory Medicine, 1986Complement is a major biologic mediation system that functions in host defense against microorganisms and other pathogens and also aids in the elimination of damaged and abnormal cells. This is accomplished by its ability to mediate the destruction of pathogens and altered cells directly through cytolytic and cytotoxic properties, as well as indirectly
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Activation of Complement by Endotoxin
Journal of Infectious Diseases, 1973Ovine erythrocytes (E) coated with endotoxin (LPS) from Salmonella typhosa 0901 have been used for characterization of the nature of a pathway by which LPS activates complement (C). E-LPS consumed C in normal guinea-pig serum in a manner identical to that in which C is consumed by LPS, that is, with marked consumption of C3-C9 and little depletion of ...
S E, Mergenhagen +2 more
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Mathematical studies of complement activation
Clinica Chimica Acta, 1983Kinetic studies of complement activation were followed by hemolytic assay. Mathematical analysis shows that the curve is composed of two exponents: the first one, which occurs during a short span of time, represents the classical pathway, the second the alternative pathway.
M A, Garrigue, J P, Muh, P, Bardos
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