Results 201 to 210 of about 341,437 (266)

Intraocular complement activation is independent of systemic complement activation and is related to macular vascular remodelling in retinal vein occlusion. [PDF]

BMC Ophthalmol
Liu H, Zhou Y, Qi J, Liang S, Guo T, Chen J, Tan H, Wang J, Xu H, Chen Z.   +9 more
europepmc   +1 more source

House Dust Mite Nebulization Drives Alarmin and Complement Activation in a Murine Tracheal Air-Liquid Interface Culture System. [PDF]

Cells
Ahmad JH, Einwohlt P, Ohms M, Wilflingseder D, Köhl J.   +4 more
europepmc   +1 more source

Modulation of immunoglobulin G oligomerization by variable domain glycans: A mechanism to regulate complement activation. [PDF]

PNAS Nexus
Biersteker R, Abendstein L, van de Bovenkamp S, van Dooren HJ, Hamers SMWR, Kwekkeboom JC, Stork EM, Drijfhout JW, Rispens T, Koeleman CAM, Wuhrer M, Trouw LA, Sharp TH, Toes REM, Kissel T.   +14 more
europepmc   +1 more source

Complement activation and humoral immune dysregulation drive progression of pediatric septic shock: a retrospective cohort study. [PDF]

Am J Transl Res
Xu P, Zhou J, Miao H, Liu Y.
europepmc   +1 more source

Increased Cardiovascular Mortality in Hemodialysis: The Role of Chronic Inflammation, Complement Activation, and Non-Biocompatibility. [PDF]

Toxins (Basel)
Pethő ÁG, Fülöp T, Orosz P, Szénási G, Tapolyai M, Dézsi L.   +5 more
europepmc   +1 more source

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Complement activation

Immunology Today, 1981
When activated, the system of serum proteins known as complement is involved in a wide variety of responses to inflammatory and noxious stimuli. In this article Eric Brown and Michael Frank review the activation of complement by the classical and alternative pathways and discuss some of its biological effects.
E J, Brown, M M, Frank
openaire   +2 more sources

Initiation of Complement Activation

Springer Seminars in Immunopathology, 1984
The complement system is an excellent one to look at as an example of a triggered enzyme system. It is found to use almost all the strategies of enzyme cascades and for initiation which were discussed in the introduction. The classical pathway is a fine example of an active zymogen form of activation and the alternative pathway is the canonical example
P J, Lachmann, N C, Hughes-Jones
openaire   +2 more sources

Activity of Mouse Complement

The Journal of Immunology, 1962
Summary A test has been devised to measure hemolytic complement activity of mouse serum. The chief requirement for detecting mouse hemolytic complement is the use of extremely large amounts of sensitizing antibody. The hemolytic factor measured in mouse serum is indeed complement.
Rosenberg, L T, Tachibana, D K
openaire   +2 more sources

Activation of Complement by Endotoxin

Journal of Infectious Diseases, 1973
Ovine erythrocytes (E) coated with endotoxin (LPS) from Salmonella typhosa 0901 have been used for characterization of the nature of a pathway by which LPS activates complement (C). E-LPS consumed C in normal guinea-pig serum in a manner identical to that in which C is consumed by LPS, that is, with marked consumption of C3-C9 and little depletion of ...
S E, Mergenhagen, R, Snyderman, J K, Phillips   +2 more
openaire   +2 more sources

Bispecific Complement Engagers for Targeted Complement Activation

The Journal of Immunology, 2023
Abstract Activation of the complement system represents an important effector mechanism of endogenous and therapeutic Abs. However, efficient complement activation is restricted to a subset of Abs due to the requirement of multivalent interactions between the Ab Fc regions and the C1 complex.
Dennis V Pedersen, Heidi Gytz, Mikael B L Winkler, Alessandra Zarantonello, Niklas Baumann, Annette G Hansen, Steffen Thiel, Gregers R Andersen, Thomas Valerius, Nick S Laursen   +9 more
openaire   +3 more sources