Results 101 to 110 of about 375,488 (189)

Complement and clotting pathway.

, 2014
Brown figures indicate proteins identified in the O. vulgaris library; and blue figures indicate the absent ones. C1q: Complement C1q binding protein; C1R: C1r subcomponent; C1S: Complement C1 subcomponent; C2: Complement component 2; C4: Complement ...
Camino Gestal (645636), Sheila Castellanos-Martínez (645635), David Arteta (429868), Susana Catarino (429867)   +3 more
core   +1 more source

Complement expression profiles in human glomerular mesangial cells, endothelial cells, podocytes and proximal tubular epithelial cells

Frontiers in Immunology
BackgroundLocal expression of complement components in the kidney has been reported sporadically in both diseased and normal kidneys. This study aimed to comprehensively characterize the expression of complement components in human glomerular mesangial ...
Yueming Gao, Qi Li, Yue Wang, Zhenling Deng   +3 more
doaj   +1 more source

Modular structure of the proteases of the C1r/C1s/MASP family and their role in complement activation.

, 2013
(A) The generic modular structure of the proteases of this family is shown. MASP-1 and -3, the two proteases coded by the MASP1 gene, exhibit a common core (yellow) and unique serine protease (SP) domains.
Christine Gaboriaud (227515), Rajesh Kumar Gupta (430759), Gérard J. Arlaud (227514), Lydie Martin (430760), Florence Teillet (430761), Laurence Serre (11711), Nicole M. Thielens (430763), Véronique Rossi (430762), Monique Lacroix (329815)   +8 more
core   +1 more source

C1s targeting antibodies inhibit the growth of cutaneous squamous carcinoma cells

Scientific Reports
Cutaneous squamous cell carcinoma (cSCC) is the most common metastatic skin cancer. The incidence of cSCC is increasing globally and the prognosis of metastatic disease is poor.
Liisa Nissinen, Pilvi Riihilä, Kristina Viiklepp, Vaishnavi Rajagopal, Michael J. Storek, Veli-Matti Kähäri   +5 more
doaj   +1 more source

Complement component C1r mediated cleavage of the heavy chain of the major histocompatibility class I antigens.

, 1992
Udgivelsesdato: 1992-Sep-16Apart from cleaving C1s, we demonstrate for the first time that: 1) at concentrations found in serum, the activated forms of the complement components C1r in addition to C1s can cleave the heavy chain of MHC class I antigens, 2)
Eriksson, H, Nissen, Mogens Holst
core   +1 more source

The complement factsbook /

, 2000
The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins.
Morley, Bernard J., Walport, Mark.
core  

Comment on "Could signal peptide complement C1r/C1s, Uegf, and Bmp1, and epidermal growth factor-containing protein 1 be a therapeutic target in the pathogenesis of preeclampsia?" [PDF]

Rev Assoc Med Bras (1992)
Cheng C, Wang Y.
europepmc   +1 more source

Corrigendum: C1R Mutations Trigger Constitutive Complement 1 Activation in Periodontal Ehlers-Danlos Syndrome

Frontiers in Immunology, 2019
Rebekka Gröbner, Ines Kapferer-Seebacher, Albert Amberger, Rita Redolfi, Fabien Dalonneau, Erik Björck, Erik Björck, Di Milnes, Isabelle Bally, Veronique Rossi, Nicole Thielens, Heribert Stoiber, Christine Gaboriaud, Johannes Zschocke   +13 more
doaj   +1 more source

Increased Serum Signal Peptide-Complement C1r/C1s, Uegf, Bmp1 (CUB)-Epithelial Growth Factor Domain-Containing Protein-1 May Have a Role in the Pathophysiology of Late-Onset Fetal Growth Restriction. [PDF]

Diagnostics (Basel)
Dinc G, Karahan SC, Guven S.
europepmc   +1 more source

Structure of the active form of the catalytic region of the complement protease C1r [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2002
V. Harmat, J. Kardos, P. Gal, O. Barabas, L. Graf, G. Naray-Szabo, P. Zavodszky   +6 more
openaire   +1 more source