Results 71 to 80 of about 796,318 (197)

Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics

open access: yesBMC Biotechnology, 2018
Background Preclinical studies have evaluated haptoglobin (Hp) polymers from pooled human plasma as a therapeutic protein to attenuate toxic effects of cell-free hemoglobin (Hb).
Christian A. Schaer   +12 more
doaj   +1 more source

Szerin proteázok az immunrendszerben: szerkezet, funkció, fiziológiai jelentőség = Serine proteases of the immune system: structure, function, physiological significance [PDF]

open access: yes, 2008
A komplement rendszer egy szerin proteázokból álló kaszkádrendszer, amely a természetes immunitás részeként fontos szerepet tölt be a fertőzések elleni védekezésben.
Ambrus, Géza   +7 more
core  

Positivity of Lyapunov exponents for a continuous matrix-valued Anderson model

open access: yes, 2007
We study a continuous matrix-valued Anderson-type model. Both leading Lyapunov exponents of this model are proved to be positive and distinct for all ernergies in $(2,+\infty)$ except those in a discrete set, which leads to absence of absolutely ...
A. Klein   +11 more
core   +1 more source

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

open access: yes, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima   +18 more
core  

The role of proteases in pathologies of the synovial joint [PDF]

open access: yes, 2008
Synovial (diarthrodial) joints are employed within the body to provide skeletal mobility and have a characteristic structure adapted to provide a smooth almost frictionless surface for articulation.
Buttle, D, Jones, GC, Riley, GP
core   +1 more source

Macrophage-derived extracellular vesicles carrying component 1r induce fibroblast activation in silicosis mice

open access: yes环境与职业医学
BackgroundSilicosis, an occupational lung disease induced by chronic silica (SiO2) exposure, is pathologically defined by progressive pulmonary fibrosis, and its associated molecular mechanisms are not yet fully elucidated.ObjectiveTo understand the ...
Ziqi WANG   +3 more
doaj   +1 more source

PAR1 activation induces the release by Schwann cells of factors promoting cell survival and neuritogenesis [PDF]

open access: yes, 2017
Protease-activated receptor 1 (PAR1) is a member of a family of four G-protein-coupled receptors which are activated by proteolytic cleavage of their N-terminal extracellular domain.
Artico, M.   +7 more
core  

A robust proof of the instability of naked singularities of a scalar field in spherical symmetry

open access: yes, 2017
Published in 1999, Christodoulou proved that the naked singularities of a self-gravitating scalar field are not stable in spherical symmetry and therefore the cosmic censorship conjecture is true in this context.
Li, Junbin, Liu, Jue
core   +1 more source

MINI-REVIEW: SYSTEMIC LUPUS ERYTHEMATOSUS AND DEFICIENCIES OF EARLY COMPONENTS OF THE COMPLEMENT CLASSICAL PATHWAY

open access: yesFrontiers in Immunology, 2016
The complement system plays an important role in the innate and acquired immune response against pathogens. It consists of more than 30 proteins found in soluble form or attached to cell membranes. Most complement proteins circulate in inactive forms and
Lourdes eIsaac, Ana Catarina Lunz Macedo
doaj   +1 more source

Complement evasion factor (CEF), a novel immune evasion factor of Streptococcus pyogenes

open access: yesVirulence, 2022
Streptococcus pyogenes, a leading human pathogen, is responsible for a wide range of diseases, including skin and soft tissue infections and severe invasive diseases. S.
Haniyeh Aghababa   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy