The insider's perspective: The intracellular complosome and immune cell dynamics in cancer. [PDF]
Bennion A, Lysaght J, Lynam-Lennon N.
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Identification of IPF specific genes expressed by lung tissue-derived fibroblasts using next generation sequencing. [PDF]
Seo EJ +8 more
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Shifting From Systemic to Precision-Targeted Complement Therapies: Opportunities and Hurdles. [PDF]
Mannes M, Zelek WM, Trouw LA.
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C/EBP-β-regulated complement hyperactivation in spleen of SFTSV-infected mice: A clue to targeted complement therapy. [PDF]
Liu Y +12 more
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Translational immunothrombosis in autoimmune Heparin-Induced thrombocytopenia: targeting the FcγRIIa-Syk-BTK and complement pathways. [PDF]
Ahmadinia M +5 more
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Complement role in kidney disease: a comprehensive review and therapeutic innovations. [PDF]
Cortez Ferreira B +7 more
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Inhibition of bFGF activity by complement C1s: covalent binding of C1s with bFGF
Cell Biochemistry and Function, 1998The first complement component C1s formed large aggregates with bFGF when bFGF and C1s were incubated at 37 degrees C overnight. Under non-reducing conditions, a part of the aggregates did not penetrate into 5% polyacrylamide gel in the presence of SDS, and the rest penetrated into 5% gel but not into 12% gel.
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Paramyosin inhibits complement C1
The Journal of Immunology, 1992Abstract We report here the results of studies showing that inhibition of C is a property of several invertebrate paramyosins. Paramyosins from Taenia solium, Schistosoma mansoni, and the mussel Mytilus edulis bind polymeric collagen and can be isolated from crude extracts of tissues by collagen affinity.
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Acta Neuropathologica, 1998In situ and in vitro studies suggest that activation of locally produced complement factors may act as a mediator between amyloid deposits and neurodegenerative changes seen in Alzheimer's disease (AD). C1-esterase inhibitor (C1-Inh), which regulates activation of C1 of the complement classical pathway, can be detected immunohistochemically in its ...
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