Results 101 to 110 of about 12,621 (239)

C1s targeting antibodies inhibit the growth of cutaneous squamous carcinoma cells

Scientific Reports
Cutaneous squamous cell carcinoma (cSCC) is the most common metastatic skin cancer. The incidence of cSCC is increasing globally and the prognosis of metastatic disease is poor.
Liisa Nissinen, Pilvi Riihilä, Kristina Viiklepp, Vaishnavi Rajagopal, Michael J. Storek, Veli-Matti Kähäri   +5 more
doaj   +1 more source

Nanofiber PVA‐Based Membranes Incorporating Functionalized Spanish Broom Derivatives for Sustainable Water Purification

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study investigates Spanish broom (Spartium junceum) as a renewable source for electrospun composite membranes in sustainable water purification. MCC and biochar were functionalized with eco‐friendly precursors and nanomaterials (i.e., HNT, β‐CDs) to develop hybrid PVA nanofiber composites.
Giulia Rando, Silvia Sfameni, Jozefien Geltmeyer, Alessandra Palella, Lorenzo Spadaro, Alberto Riminucci, Karen De Clerck, Maria Rosaria Plutino   +7 more
wiley   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

Movement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar, Pinky Agarwal, Karen Anderson, Daniel Claassen, Marissa Dean, Andrew Duker, Burton Scott, Benjamin Hoehn, Ann Mongan, Ping Lin, Ellen Cahir‐McFarland, Lori Taylor, Glenn Morrison, Ted Yednock, Sanjay Keswani, Henk‐Andre Kroon   +15 more
wiley   +1 more source

The Role of Cold Atmospheric Plasma in Surface Modification and Adhesion Behavior of Polypropylene/Flax Biocomposites

Polymer Composites, EarlyView.
Effects of plasma surface treatment on adhesive bonding of PP/flax biocomposites. ABSTRACT The emphasis on environmental sustainability has accelerated the adoption of biocomposites as alternatives to synthetic composites. However, their low surface energy may limit adhesion in bonding applications.
Asil Ayaz, Kutlay Sever, Gizem Dilara Özdemir, Utku Kürşat Ercan   +3 more
wiley   +1 more source

MINI-REVIEW: SYSTEMIC LUPUS ERYTHEMATOSUS AND DEFICIENCIES OF EARLY COMPONENTS OF THE COMPLEMENT CLASSICAL PATHWAY

Frontiers in Immunology, 2016
The complement system plays an important role in the innate and acquired immune response against pathogens. It consists of more than 30 proteins found in soluble form or attached to cell membranes. Most complement proteins circulate in inactive forms and
Lourdes eIsaac, Ana Catarina Lunz Macedo
doaj   +1 more source

Moment bounds for a class of fractional stochastic heat equations [PDF]

, 2014
We consider fractional stochastic heat equations of the form $\frac{\partial u_t(x)}{\partial t} = -(-\Delta)^{\alpha/2} u_t(x)+\lambda \sigma (u_t(x)) \dot F(t,\, x)$. Here $\dot F$ denotes the noise term.
Foondun, Mohammud, Liu, Wei, Omaba, McSylvester   +2 more
core   +1 more source

Surface Engineering of Ti3C2Tx MXenes via Silanol Functionalization for Improved Electrochemical Performance

Small, EarlyView.
This study explores the covalent functionalization of Ti3C2Tx using 5,5′‐bis(triisopropoxysilyl)‐2,2′‐bipyridine in different solvents, revealing that only m‐xylene enables effective covalent bonding, ensuring structural stability and preventing layer swelling.
Abelardo Sánchez‐Oliva, Verónica Montes‐García, Ke Li, Kaitlyn Prenger, Xuyun Guo, Iwona Janica, Wojciech Kukułka, Adrián Tamayo, Pilar Prieto, Paolo Samorì, Valeria Nicolosi, Artur Ciesielski   +11 more
wiley   +1 more source

Influence of Temperature on the Reliability of Graphene‐Based Ozone Sensors

Small, EarlyView.
The reliability and stability of inkjet‐printed graphene flake sensors are evaluated. Stress assessments take place in ozone‐rich environments and at elevated temperatures, with the observation of a change in resistance. Surface‐sensitive techniques serve to investigate the failure and degradation mechanisms of printed graphene.
Archa Jain, Kathrin Ganzhorn, Aleksandr Baklanov, Tim Schaffus, Werner Breuer, Jasper Ruhkopf, Janio Venturini, Sebastian Troll, Annalisa Cappellani, Max C. Lemme   +9 more
wiley   +1 more source

Novel insights into the treatment of complement-mediated hemolytic anemias

Therapeutic Advances in Hematology, 2019
Complement-mediated hemolytic anemias can either be caused by deficiencies in regulatory complement components or by autoimmune pathogenesis that triggers inappropriate complement activation.
Sigbjørn Berentsen, Anita Hill, Quentin A. Hill, Tor Henrik Anderson Tvedt, Marc Michel   +4 more
doaj   +1 more source

Ultrasensitive MicroRNA Detection Combining Reduced Graphene Oxide Electrolyte‐Gated Transistors and Machine Learning

Small, EarlyView.
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo, Gabrielle Coelho Lelis, Maria Luisa Braunger, Stefano Casalini, Yasmin Watanabe, Gabriel Ravanhani Schleder, Wilson Tiago Fonseca, Rafael Furlan de Oliveira   +7 more
wiley   +1 more source