Results 41 to 50 of about 97,543 (311)

C3 Glomerulopathy: A Rare Entity with Future Directions

Revista Portuguesa de Nefrologia e Hipertensão, 2023
C3 glomerulopathies are a rare group of glomerular diseases resulting from excessive activation of the alternative complement pathway. The pathogenesis involves genetic, acquired, or immunologic defects in regulators of the alternative complement ...
Sara Vilela, Catarina Cardoso, Sara Barreto, Gonçalo Cruz, Pedro Bravo, Cristina Santos   +5 more
doaj   +1 more source

C3 glomerulonephritis with genetically confirmed C3 deficiency in a pediatric patient: a case report [PDF]

Childhood Kidney Diseases
Complement component 3 glomerulonephritis (C3GN) is a rare kidney disease characterized by complement dysregulation that results in prominent complement component 3 (C3) deposition in the kidneys. The clinical course of C3GN varies from mild hematuria to
Hae Min Kim, Jae Il Shin, Ji Hong Kim, Jiyoung Oh, Ji-Man Kang, Hee Gyung Kang, Seong Heon Kim, Byoung Soo Cho, Keum Hwa Lee   +8 more
doaj   +1 more source

Associations Between Complement Components and Vitamin D and the Physical Activities of Daily Living Among a Longevous Population in Hainan, China

Frontiers in Immunology, 2020
Background: Vitamin D and complement components shared some common pathophysiological pathways in the musculoskeletal system, circulation, and metabolism, which were linked to physical function.
Chi Zhang, Chi Zhang, Shihui Fu, Minghao Zhao, Deping Liu, Deping Liu, Yali Zhao, Yao Yao, Yao Yao   +8 more
doaj   +1 more source

C3: High-performance and low-complexity neural compression from a single image or video [PDF]

arXiv, 2023
Most neural compression models are trained on large datasets of images or videos in order to generalize to unseen data. Such generalization typically requires large and expressive architectures with a high decoding complexity. Here we introduce C3, a neural compression method with strong rate-distortion (RD) performance that instead overfits a small ...
arxiv  

Asteroseismic properties of solar-type stars observed with the NASA K2 mission: results from Campaigns 1-3 and prospects for future observations [PDF]

, 2016
We present an asteroseismic analysis of 33 solar-type stars observed in short cadence during Campaigns (C) 1-3 of the NASA K2 mission. We were able to extract both average seismic parameters and individual mode frequencies for stars with dominant frequencies up to ~3300{\mu}Hz, and we find that data for some targets are good enough to allow for a ...
arxiv   +1 more source

Kallikrein Cleaves C3 and Activates Complement

Journal of Innate Immunity, 2017
The human plasma contact system is an immune surveillance system activated by the negatively charged surfaces of bacteria and fungi and includes the kallikrein-kinin, the coagulation, and the fibrinolytic systems. Previous work shows that the contact system also activates complement, and that plasma enzymes like kallikrein, plasmin, thrombin, and FXII ...
Sarah Irmscher, Döring N, Hortense Slevogt, Christine Skerka, Jo Eah, Niklas Beyersdorf, Christine Dunker, Shanshan Luo, Ilse D. Jacobsen, Kopka I, Luke D. Halder, Peter F. Zipfel, Stefan Lorkowski   +12 more
openaire   +3 more sources

Platelet-bound complement (C3) in immune thrombocytopenia [PDF]

Blood, 1977
The fixation of complement to the circulating platelet in immune thrombocytopenia was detected by measurement of one of the complement components, C3, on the surface of platelets from patients with idiopathic thrombocytopenic purpura (ITP) and systemic lupus erythematosus (SLE) using the anti-C3 consumption assay.
Thomas W. Hauch, Wendell F. Rosse
openaire   +4 more sources

Complement C3 and Nonalcoholic Fatty Liver Disease in Chronic Kidney Disease Patients: A Pilot Study

Kidney & Blood Pressure Research, 2020
Context: Evidences have suggested complement C3 is a biomarker for nonalcoholic fatty liver disease (NAFLD) in the general population. Objective: The present study was conducted to explore the predictive function of C3 for NAFLD in chronic kidney disease
Binbin Pan, Xin Wan, Mengqing Ma, Changchun Cao   +3 more
doaj   +1 more source

Complement C3 and C5 deficiency affects fracture healing. [PDF]

PLoS ONE, 2013
There is increasing evidence that complement may play a role in bone development. Our previous studies demonstrated that the key complement receptor C5aR was strongly expressed in the fracture callus not only by immune cells but also by bone cells and ...
Christian Ehrnthaller, Markus Huber-Lang, Per Nilsson, Ronny Bindl, Simon Redeker, Stefan Recknagel, Anna Rapp, Tom Mollnes, Michael Amling, Florian Gebhard, Anita Ignatius   +10 more
doaj   +1 more source

A Novel Homozygous In-Frame Deletion in Complement Factor 3 Underlies Early-Onset Autosomal Recessive Atypical Hemolytic Uremic Syndrome - Case Report

Frontiers in Immunology, 2021
Background and ObjectivesAtypical hemolytic uremic syndrome (aHUS) is mostly attributed to dysregulation of the alternative complement pathway (ACP) secondary to disease-causing variants in complement components or regulatory proteins.
Shirley Pollack, Shirley Pollack, Israel Eisenstein, Adi Mory, Tamar Paperna, Ayala Ofir, Hagit Baris-Feldman, Karin Weiss, Nóra Veszeli, Dorottya Csuka, Revital Shemer, Fabian Glaser, Zoltán Prohászka, Daniella Magen, Daniella Magen   +14 more
doaj   +1 more source