Results 131 to 140 of about 27,207 (241)

Renal C3 complement component: feed forward to diabetic kidney disease [PDF]

, 2015
BACKGROUND: Diabetic nephropathy is the main cause of end-stage renal disease and has reached epidemic proportions. METHODS: Comprehensive genomic profiling (RNAseq) was employed in the ZS (F1 hybrids of Zucker and spontaneously hypertensive heart ...
Dominguez, Jesus H., Kelly, Katherine J., Liu, Yunlong, Zhang, Jizhong   +3 more
core   +2 more sources

Mice lacking acylation stimulating protein (ASP) have delayed postprandial triglyceride clearance

Journal of Lipid Research, 1999
Acylation stimulating protein (ASP) is a 76 amino acid fragment of the third component of complement (C3) which is generated by the interaction of adipsin and factor B with C3.
I. Murray, A.D. Sniderman, K. Cianflone
doaj   +1 more source

Supplementary Figures S1-S7 from The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer

, 2023
Quaovi H. Sodji, Dhanya K. Nambiar, Vignesh Viswanathan, Rie von Eyben, Deana R.C. Colburg, Michael S. Binkley, Caiyun G. Li, Monica M. Olcina, Daniel T. Chang, Quynh‐Thu Le, Amato Giaccia   +10 more
openalex   +3 more sources

Data from The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer

, 2023
Quaovi H. Sodji, Dhanya K. Nambiar, Vignesh Viswanathan, Rie von Eyben, Deana R.C. Colburg, Michael S. Binkley, Caiyun G. Li, Monica M. Olcina, Daniel T. Chang, Quynh‐Thu Le, Amato Giaccia   +10 more
openalex   +1 more source

Association of age-related macular degeneration with complement activation products, smoking, and single nucleotide polymorphisms in South Carolinians of European and African descent

Molecular Vision, 2019
Purpose: Smoking and the incidence of age-related macular degeneration (AMD) have been linked to an overactive complement system. Here, we examined in a retrospective cohort study whether AMD-associated single nucleotide polymorphisms (SNPs), smoking ...
Bärbel Rohrer, Ashley Frazer-Abel, Anthony Leonard, Rinki Ratnapriya, Tyson Ward, Alexandra Pietraszkiewicz, Elizabeth O’Quinn, Katherine Adams, Anand Swaroop, Bethany Jacobs Wolf   +9 more
doaj  

Complement activation pathways in murine immune complex-induced arthritis and in C3a and C5a generationin vitro [PDF]

, 2009
Nirmal K. Banda, Brandt Levitt, Allyson Wood, Kazue Takahashi, Gregory L. Stahl, V. Michael Holers, William P. Arend   +6 more
openalex   +1 more source

Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity. [PDF]

J Clin Invest, 2023
Stokowska A, Aswendt M, Zucha D, Lohmann S, Wieters F, Morán Suarez J, Atkins AL, Li Y, Miteva M, Lewin J, Wiedermann D, Diedenhofen M, Torinsson Naluai Å, Abaffy P, Valihrach L, Kubista M, Hoehn M, Pekny M, Pekna M.   +18 more
europepmc   +1 more source

Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity

Experimental Biology and Medicine
Investigations on some innate immunity proteins can yield misleading information, as investigators often rely on static measurements and assume a direct correlation to function. As protein function is often not directly proportional to protein abundance,
Douglas D. Fraser, Douglas D. Fraser, Swapan Roy, Matt Kuruc, Maritza Quintero, Logan R. Van Nynatten, Gediminas Cepinskas, Gediminas Cepinskas, Haiyan Zheng, Amenah Soherwardy, Devjit Roy   +10 more
doaj   +1 more source

Complement C3a Activates Astrocytes to Promote Medulloblastoma Progression through TNF -α

, 2021
Biao Gong, Duancheng Guo, Chaonan Zheng, Zhen Ma, Jie Zhang, Yanghui Qu, Xinhua Li, Gen Li, Li Zhang, Yuan Wang   +9 more
openalex   +1 more source

Novel structural determinants of the human neutrophil chemotactic activity of leukotriene B. [PDF]

, 1981
A specific 5(S),12(R)-dihydroxy-eicosa-6,8,10(trans/trans/cis), 14(cis)-tetraenoic acid, designated leukotriene B, is generated by the lipoxygenation and subsequent enzymatic hydration of arachidonic acid in a variety of leukocytes. Leukotriene B elicits
Goetzl, EJ, Pickett, WC
core