Results 81 to 90 of about 792,617 (213)

Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN) [PDF]

Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2009
Staphylococcus aureus secretes a number of small proteins that effectively attenuate the human innate immune response. Among these, the staphylococcal complement-inhibitor protein (SCIN) disrupts the function of the complement component 3 (C3) convertase that is initiated through either the classical or the alternative pathway and thereby prevents ...
Brandon L, Garcia, Apostolia, Tzekou, Kasra X, Ramyar, William J, McWhorter, Daniel, Ricklin, John D, Lambris, Brian V, Geisbrecht   +6 more
openaire   +2 more sources

Metaproteome Analysis of Short‐Term Thermal Stress in Three Sympatric Coral Species Reveals Divergent Host Responses

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Short‐term thermal stress triggers distinct molecular responses in three sympatric coral species with contrasting thermal resilience. Proteomic and metabolomic profiling reveal both species‐specific and limited shared pathways underlying these stress responses.
Shrinivas Nandi, Timothy G. Stephens, Erin E. Chille, Samantha Goyen, Line K. Bay, Debashish Bhattacharya   +5 more
wiley   +1 more source

How Escherichia coli Circumvent Complement-Mediated Killing

Frontiers in Immunology, 2017
Complement is a crucial arm of the innate immune response against invading bacterial pathogens, and one of its main functions is to recognize and destroy target cells.
Angela S. Barbosa, Afonso G. Abreu, Afonso G. Abreu   +2 more
doaj   +1 more source

Complement Hyperactivation Is Mediated by Alternative and Lectin Pathways During Early Phase of Severe Vaccination‐Omicron BA.5 Infection

Journal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Jinpeng Cao, Gang Yang, Tingting Cui, Jian Qin, Deyi Huang, Shiqin Jin, Xiaoyun Yang, Mingzhu Huang, Xiaoling Su, Siyi Liu, Yingjiao Xia, Shidong Deng, Chengna Luo, Zhuxiang Zhao, Yunhui Zhang, Nanshan Zhong, Zhongfang Wang   +16 more
wiley   +1 more source

Enhanced expression of human monocyte complement (C3b) receptors by chemoattractants. [PDF]

Clinical and experimental immunology, 1980
The capacity of various leucoattractants to enhance, or unfold, receptors for complement (C3b) on human blood monocytes has been studied. A number of recognized monocyte chemoattractants including casein, supernatants from C. parvum 10390 and from human lymphocytes (cultured either in the presence or absence of phytohaemagglutinin) and the formyl ...
GLASS, EJ, KAY, AB
openaire   +1 more source

Complement Receptor Subtypes C3b and C3d in Lymphatic Tissue and Follicular Lymphoma [PDF]

British Journal of Cancer, 1978
To substantiate the origin of follicular (nodular) lymphoma cells from germinal-centre cells, the lymphoma cells from 7 patients with follicular lymphoma and from 9 tonsils and 2 lymph nodes were studied for the presence and distribution of complement-receptor subtypes (i.e., the receptors for C3b and C3d).
H, Stein, U, Siemssen, K, Lennert
openaire   +2 more sources

Plasma Proteomic Signatures of Pediatric Sepsis Reveal Persistent Inflammation and Phase‐Specific Biomarkers

FASEB BioAdvances, Volume 8, Issue 3, March 2026.
We enrolled a pediatric sepsis cohort at acute and recovery phases for plasma proteomics analysis. Abundantly expressed proteins in sepsis were identified and subjected to machine learning. In addition, the data was compared to adult sepsis and sterile inflammation.
Fahd Alhamdan, Yi‐Cheng Sin, Erik Malm, Hanna Van Pelt, Samuel Kim, LeeAnn Higgins, Yue Chen, Koichi Yuki   +7 more
wiley   +1 more source

Binding of fluid-phase complement components C3 and C3b to human lymphocytes [PDF]

Biochemical Journal, 1981
It is known that a population of B-lymphocytes has receptors for the third component of complement, C3, and that these lymphocytes may be identified by their ability to form rosettes with sheep erythrocytes coated with covalently bound fragments of complement component C3.
E, Sim, R B, Sim
openaire   +2 more sources

Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia, Cesar Augusto Roque‐Borda, Fernando Rogério Pavan, Marlus Chorilli   +3 more
wiley   +1 more source

Purified complement C3b triggers phagocytosis and activation of human neutrophils via Complement receptor 1

, 2022
Abstract The complement system provides vital immune protection against infectious agents by labeling them with complement fragments that enhance phagocytosis by immune cells. Many details of complement-mediated phagocytosis remain elusive, partly because it is difficult to study the role of individual complement proteins on target surfaces ...
Elena Boero, Ronald D. Gorham, Emmet A. Francis, Jonathan Brand, Lay Heng Teng, Dennis J. Doorduijn, Maartje Ruyken, Christian Lehmann, Admar Verschoor, Kok P.M. Kessel, Volkmar Heinrich, Suzan H.M. Rooijakkers   +11 more
openaire   +1 more source