Results 91 to 100 of about 905,894 (352)

Investigation on the Influence of Protein Corona and Platelet Adhesion on Storage Bag Surface on the Platelet Storage Lesion

open access: yesAdvanced Healthcare Materials, EarlyView.
Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra   +7 more
wiley   +1 more source

The role of complement in Streptococcus pneumoniae-associated haemolytic uraemic syndrome [PDF]

open access: yes, 2013
Background. Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase- producing pathogens, such as Streptococcus pneumoniae. Increasing data
Szilágyi, Ágnes
core  

Upward-closed hereditary families in the dominance order [PDF]

open access: yes, 2019
The majorization relation orders the degree sequences of simple graphs into posets called dominance orders. As shown by Hammer et al. and Merris, the degree sequences of threshold and split graphs form upward-closed sets within the dominance orders they ...
Barrus, Michael D., Guillaume, Jean
core   +4 more sources

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam   +9 more
wiley   +1 more source

Effect of thiol compounds on human complement component C4 [PDF]

open access: yesBiochemical Journal, 1993
Thiol compounds have been investigated as inhibitors of the covalent binding reaction of human complement protein C4 using Sepharose-C1s as a combined activating and binding surface. o- and p-substituted aminothiophenols are equally effective inhibitors, whereas the m-substituted compound is a less potent inhibitor. The anti-hypertensive drug captopril
A Gibb, Edith Sim, S Edmonds
openaire   +3 more sources

Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications

open access: yesAdvanced Materials, EarlyView.
Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach   +4 more
wiley   +1 more source

Adsorption and Separation by Flexible MOFs

open access: yesAdvanced Materials, EarlyView.
Flexible metal–organic frameworks (MOFs) present significant potential for gas storage and separation due to their structural dynamic. This review explores the rationale behind the flexible MOFs' enhanced working capacity and separation factors. It also addresses key challenges, including phase transition kinetics, crystal robustness, cycling, shaping,
Irena Senkovska   +4 more
wiley   +1 more source

Complement-Mediated Opsonic Activity in Normal and Infected Human Cerebrospinal Fluid: Early Response During Bacterial Meningitis [PDF]

open access: yes, 2017
A local defense mechanism in bacterial meningitis was evaluated in humans by measuring complement-mediated opsonic activity (CMOA) in normal and infected cerebrospinal fluid (CSF) with a complement-dependent phagocytic bactericidal assay. CMOA was absent
Lambert, Paul-Henri   +4 more
core  

Simple Irreducible Subgroups of Exceptional Algebraic Groups [PDF]

open access: yes, 2014
A closed subgroup of a semisimple algebraic group is called irreducible if it lies in no proper parabolic subgroup. In this paper we classify all irreducible subgroups of exceptional algebraic groups $G$ which are connected, closed and simple of rank at ...
Thomas, Adam
core   +6 more sources

Complement Component C4 Regulates the Development of Experimental Autoimmune Uveitis through a T Cell-Intrinsic Mechanism

open access: yesFrontiers in Immunology, 2017
In addition to its conventional roles in the innate immune system, complement has been found to directly regulate T cells in the adaptive immune system.
Lingjun Zhang   +4 more
doaj   +1 more source

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