Results 11 to 20 of about 158,014 (317)

SERUM C3 AND SERUM C4 COMPLEMENT IN PATIENTS WITH BURN TRAUMA AND CORRELATION WITH BURN INJURY SEVERITY

Sanamed, 2022
Introduction: Burns, depending on the degree of severity, induce a significant pathophysiological response in the body. The complement system participates in the body's defenses as well as in immune responses after burn-induced trauma. Objectives: The
Arslanagic Selma, Karamehic Jasenko
doaj   +1 more source

Associations Between Genotype and Peripheral Complement Proteins in First-Episode Psychosis: Evidences From C3 and C4

Frontiers in Genetics, 2021
Schizophrenia is a common neuropsychiatric disorder with complex pathophysiology. Recent reports suggested that complement system alterations contributed to pathological synapse elimination that was associated with psychiatric symptoms in schizophrenia ...
Yu Chen, Yu Chen, Zhenguo Zhao, Zhenguo Zhao, Fen Lin, Fen Lin, Lifang Wang, Lifang Wang, Zheng Lin, Weihua Yue, Weihua Yue, Weihua Yue   +11 more
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The Assessment of Complement Proteins in Patients With Severe COVID-19 [PDF]

International Journal of Basic Science in Medicine, 2021
Introduction: The complement system, consisting of more than 20 soluble proteins, has a crucial role in innate immunity and inflammation and eliminates pathogens and viral infections.
Ali Ghazavi, Ghasem Mosayebi, Nafiesh Keshavarzian, Somayeh Rabiemajd, Ali Ganji   +4 more
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The complement component C4 of mammals [PDF]

Biochemical Journal, 1990
Human complement component C4 is coded by tandem genes located in the HLA class III region. The products of the two genes, C4A and C4B, are different in their activity. This difference is due to a degree of ‘substrate’ specificity in the covalent binding reactions of the two isotypes. Mouse also has a duplicated locus, but only one gene produces active
Alister W. Dodds, S K A Law
openaire   +3 more sources

Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components [PDF]

, 2013
Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
A Alitalo, A Alitalo, A Alitalo, A Seling, AC Steere, AM Blom, Andreas Klos, AP van Dam, B Stevenson, C Hammerschmidt, C Siegel, C Siegel, Christine Skerka, Claudia Hammerschmidt, CS Brooks, Dania Richter, E Diza, F Strle, Franz-Rainer Matuschka, H Jiang, H Michel, J Hellwage, J Pietikainen, J Potempa, Jasmin Schwab, JD Lambris, JV McDowell, K Hartmann, K Haupt, K Kurtenbach, K Kurtenbach, K Saito, K Whaley, KM Hovis, KP Hunfeld, L Beinrohr, M Collares-Pereira, M Jusko, M Józsi, MJ Walport, MK Pangburn, MR Bhide, MR Bhide, MR Kenedy, MS Metts, N Marr, ND van Burgel, P Herzberger, P Herzberger, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Ramu, Peter F. Zipfel, Peter Kraiczy, PF Zipfel, PF Zipfel, R Dieterich, R Wallich, Reinhard Wallich, RG Discipio, RJ Ziccardi, S Breitner-Ruddock, S Grosskinsky, S Grosskinsky, S Heinen, S Kühn, SC Bock, SG Rijpkema, SH Rooijakkers, T Fujita, T Fujita, V Brade, Y Terao   +76 more
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Complement content in plasma under different storage conditions

Zhongguo shuxue zazhi, 2023
Objective To investigate the changes in complement content in component blood before blood transfusion. Methods 180 samples from 20 plasma donors were collected at different stages of the preparation process, stored at different temperatures and time ...
Zhi HAN, Yujie HAN, Haihong ZHANG
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Hepatitis C virus NS3/4A protease inhibits complement activation by cleaving complement component 4. [PDF]

PLoS ONE, 2013
BACKGROUND: It has been hypothesized that persistent hepatitis C virus (HCV) infection is mediated in part by viral proteins that abrogate the host immune response, including the complement system, but the precise mechanisms are not well understood.
Seiichi Mawatari, Hirofumi Uto, Akio Ido, Kenji Nakashima, Tetsuro Suzuki, Shuji Kanmura, Kotaro Kumagai, Kohei Oda, Kazuaki Tabu, Tsutomu Tamai, Akihiro Moriuchi, Makoto Oketani, Yuko Shimada, Masayuki Sudoh, Ikuo Shoji, Hirohito Tsubouchi   +15 more
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Hypocomplementemia during tocilizumab treatment

Medicine, 2022
. Hypocomplementemia has been reported in patients with rheumatoid arthritis treated with tocilizumab (TCZ), but its long-term consequences are unknown.
Amir Bieber, MD, Doron Markovits, MD, PhD, Kohava Toledano, MD, Yonit Tavor, MD, Reuven Mader, MD, Alexandra Balbir-Gurman, MD, Yolanda Braun-Moscovici, MD   +6 more
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Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]

, 2020
ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza, Arriens, Cristina, Collins, Christopher E, Dervieux, Thierry, Kalunian, Kenneth C, Massarotti, Elena M, Narain, Sonali, O'Malley, Tyler, Putterman, Chaim, Ramsey-Goldman, Rosalind, Saxena, Amit, Wallace, Daniel J, Weinstein, Arthur   +12 more
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Increased activation product of complement 4 protein in plasma of individuals with schizophrenia

Translational Psychiatry, 2021
Structural variation in the complement 4 gene (C4) confers genetic risk for schizophrenia. The variation includes numbers of the increased C4A copy number, which predicts increased C4A mRNA expression.
Agnieszka Kalinowski, Joanna Liliental, Lauren A. Anker, Omer Linkovski, Collin Culbertson, Jacob N. Hall, Reenal Pattni, Chiara Sabatti, Douglas Noordsy, Joachim F. Hallmayer, Elizabeth D. Mellins, Jacob S. Ballon, Ruth O’Hara, Douglas F. Levinson, Alexander E. Urban   +14 more
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