Results 11 to 20 of about 942,109 (243)
Complement C4 Prevents Viral Infection through Capsid Inactivation. [PDF]
Cell Host Microbe, 2019 The complement system is vital for anti-microbial defense. In the classical pathway, pathogen-bound antibody recruits the C1 complex (C1qC1r2C1s2) that initiates a cleavage cascade involving C2, C3, C4, and C5 and triggering microbial clearance. We demonstrate a C4-dependent antiviral mechanism that is independent of downstream complement components ...
Bottermann M +15 more
europepmc +6 more sources
Definitions, 2020 Complement C4-B (1744 aa, ~193 kDa) is encoded by the human C4B and C4B_2 genes. This protein is involved in the propagation of the classical complement pathway.
semanticscholar +2 more sources
Serum complement C4 is an important prognostic factor for IgA nephropathy: a retrospective study. [PDF]
BMC Nephrol, 2019 BackgroundIgA nephropathy (IgAN) is the most common glomerulonephritis worldwide and is an important cause of end-stage renal disease (ESRD). Exploring novel biomarkers is necessary for predicting the disease activity and progression of IgAN patients ...
Bi TD +6 more
europepmc +2 more sources
Evaluation of complement components C3 and C4 in serum of patient with neoplastic diseases
مجلة علوم ذي قار, 2019 The aim of this study is to evaluate the level of complement components C3 and C4 in serum of cancer patients to find which activation pathway of the complment system has the more effect in these cases .
Zeenah weheed Atwan +2 more
doaj +7 more sources
Serum Complement C4 Levels Are a Useful Biomarker for Predicting End-Stage Renal Disease in Microscopic Polyangiitis. [PDF]
Int J Mol Sci, 2023 Matsuda S +10 more
europepmc +3 more sources
Low complement items play different roles on the classification performance of SLICC-2012, EULAR/ACR-2019, and SLERPI [PDF]
Frontiers in MedicineObjectivesThis study aimed to explore the association of low complement items with the performance of the systemic lupus erythematosus (SLE) classification criteria.MethodsThis study included 352 patients with SLE and 385 individuals with positive ...
Shanshan Chen +5 more
doaj +2 more sources
Effect of olanzapine on changes in serum complement factors levels in patients with first-episode schizophrenia [PDF]
BMC PsychiatryObjective An increasing number of studies have demonstrated that patients with schizophrenia (SCZ) exhibit complement system disorders, and alterations in serum complement factor levels may serve as biomarkers for guiding the diagnosis, prognosis, and ...
Yin Cao +5 more
doaj +2 more sources
Complement C4, C4A and C4a – What they do and how they differ [PDF]
Brain, Behavior, & Immunity - HealthMeike Heurich +2 more
doaj +2 more sources