Association between copy number variation of complement component C4 and Graves' disease [PDF]
, 2011 Background Gene copy number of complement component C4, which varies among individuals, may determine the intrinsic strength of the classical complement pathway.
Yu-Huei Liu +7 more
core +2 more sources
Complement C4 allotypes and psoriasis.
Clinical Chemistry, 1989 Complement C4 allotypes were studied in a group of 100 patients with psoriasis vulgaria. Frequency of C4A and C4B allotypes in 46 randomly selected unrelated healthy subjects of the same ethnic origin, previously described, was taken as a control pattern.
Čvorišćec, Dubravka +2 more
openaire +3 more sources
Cutaneous vasculitis and recurrent infection caused by deficiency in complement factor I [PDF]
, 2018 Cutaneous leukocytoclastic vasculitis arises from immune complex deposition and dysregulated complement activation in small blood vessels. There are many causes, including dysregulated host response to infection, drug reactions, and various autoimmune ...
Despina Eleftheriou +9 more
core +2 more sources
Complementing antibody profiles: Assessing antibody function on antigen microarrays [PDF]
, 2012 Antibody effector functions other than neutralization depend on interactions with soluble and cellular components of the immune system. Antigen recognition is usually oligoclonal, with the different clones of antibodies belonging to different ...
Papp, Krisztián +2 more
core +1 more source
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation [PDF]
, 2015 Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation.
Agostinis, C +9 more
core +3 more sources
Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
core +1 more source
Complement system biomarkers in first episode psychosis [PDF]
, 2019 Several lines of evidence implicate immunological/inflammatory factors in development of schizophrenia. Complement is a key driver of inflammation, and complement dysregulation causes pathology in many diseases.
Di Forti, Marta +8 more
core +2 more sources
Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]
, 2020 ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza +12 more
core +2 more sources
Pharmacological management of immune and oxidative disturbances in patients with encephalopathy on the background of hypertension [PDF]
, 2016 Inclusion of a comprehensive drug treatment of patients with discirculatory encephalopathy cerebrolysin combination with meksidol normalizes the concentration of C3 and C4 components of the complement system, IgG, malondialdehyde, catalase activity ...
Bistrova, N. A. +2 more
core +2 more sources
Renal C3 complement component: feed forward to diabetic kidney disease [PDF]
, 2015 BACKGROUND: Diabetic nephropathy is the main cause of end-stage renal disease and has reached epidemic proportions. METHODS: Comprehensive genomic profiling (RNAseq) was employed in the ZS (F1 hybrids of Zucker and spontaneously hypertensive heart ...
Dominguez, Jesus H. +3 more
core +2 more sources