Results 31 to 40 of about 515,713 (283)

Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components [PDF]

, 2013
Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Christine Skerka, Skerka, Christine, Schwab, Jasmin, Peter Kraiczy (36173), Jasmin Schwab (105418), Christine Skerka (105424), Zipfel, Peter F., Richter, Dania, Peter Kraiczy, Peter F Zipfel, Dania Richter (105422), Franz-Rainer Matuschka, Peter F. Zipfel, Kraiczy, Peter, Reinhard Wallich (57833), Matuschka, Franz-Rainer, Dania Richter, Claudia Hammerschmidt, Wallich, Reinhard, Hammerschmidt, Claudia, Reinhard Wallich, Jasmin Schwab, Claudia Hammerschmidt (105420), Peter F. Zipfel (105431), Franz-Rainer Matuschka (105426)   +24 more
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Biochemical and functional studies of a novel complement inhibitor, CRIT, with its interaction partners [PDF]

, 2005
Complement C2 receptor trispanning (CRIT), a three transmembrane receptor, was first discovered on the surface of the parasite Schistosoma haematobium and formerly termed Schistosoma trispanning orphan receptor (Sh-TOR). This receptor acts as decoy C2-
Hui, Kwok-Min
core   +1 more source

Complement C4 allotypes and psoriasis.

Clinical Chemistry, 1989
Complement C4 allotypes were studied in a group of 100 patients with psoriasis vulgaria. Frequency of C4A and C4B allotypes in 46 randomly selected unrelated healthy subjects of the same ethnic origin, previously described, was taken as a control pattern.
Čvorišćec, Dubravka, Stavljenić Rukavina, Ana, Vukelić, B.   +2 more
openaire   +3 more sources

Carbohydrate recognition and complement activation by rat ficolin-B [PDF]

, 2010
Ficolins are innate immune components that bind to PAMPs and structures on apoptotic cells. Humans produce two serum forms (L-and H-ficolin) and a leukocyte-associated form (M-ficolin), whereas rodents and most other mammals produce ficolins-A and -B ...
Roscher, Silke, Umakhanth Venkatraman Girija, Russell Wallis, Mitchell, Daniel A., Girija, Umakhanth Venkatraman, Wallis, Russell, Wallis, R., Mitchell, D. A., Venkatraman Girija, U., Roscher, S., Daniel A. Mitchell, Silke Roscher   +11 more
core   +1 more source

Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis

, 2022
Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk.
Aguirre, MA, Ríos, R, Castellvi, I, Nash, P, Rodríguez-Rodríguez, L, Carreira, P, García-Hernández, FJ, Fernández-Nebro, A, Acosta-Herrera, M, Callejas, JL, Simeón-Aznar, CP, Fernández-Gutiérrez, B, Kerick, M, Portales, RG, et al., Assassi, S   +15 more
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A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo [PDF]

, 2000
The strongest susceptibility genes for the development of systemic lupus erythematosus (SLE) in humans are null mutants of classical pathway complement proteins. There is a hierarchy of disease susceptibility and severity according to the position of the
H. Terence Cook, Savill, John, Henson, Peter M, Cook, HT, Valerie A. Fadok, Taylor, P.R, Henson, PM, Mark J. Walport, Savill, JS, Walport, MJ, Philip R. Taylor, John S. Savill, Michael C. Carroll, Botto, M, Andrews, Mark, Taylor, PR, Fadok, Valerie A, Anna Carugati, Carroll, Michael C, Walport, Mark J, Carroll, MC, Marina Botto, Carugati, A, Peter M. Henson, Andrews, M, Mark Andrews, Botto, Marina, Fadok, VA, Carugati, Anna, Cook, H. Terence   +29 more
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The Role of Complement in Cancer Immunotherapy [PDF]

, 2022
The dual role of complement in both cancer development and treatment has been investigated extensively and is characterized by a substantial literature that documents the conditions in which complement can either enhance tumor growth or promote the ...

core   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Schmid, Ralf, Schwaeble, Wilhelm J., Wilhelm J. Schwaeble, Anthony H. Keeble, Russell Wallis, Mitchell, Daniel A., Keeble, Anthony H., Wallis, Russell, Ralf Schmid, Daniel A. Mitchell   +9 more
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Complement component C4-like protein in Atlantic cod (Gadus morhua L.) - Detection in ontogeny and identification of post-translational deimination in serum and extracellular vesicles [PDF]

, 2019
The complement system is a critical part of teleost immune defences, with complement component C4 forming part of the classical and lectin pathways.
Lange, S., Kraev, Igor, Dodds, Alister W., Magnadottir, B., Lange, Sigrun, Dodds, A.W., Magnadóttir, Bergljót, Kraev, I.   +7 more
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Crosstalk Between Activated Platelets and the Complement System [Elektronisk resurs]

, 2010
Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems.
Hamad, Osama A.,, Truedsson, Lennart,, Ekdahl-Nilsson, Kristina,, Nilsson, Bo,   +3 more
core   +8 more sources