Results 31 to 40 of about 49,973 (249)

Cell-bound complement activation products associate with lupus severity in SLE

Lupus Science and Medicine, 2020
Objectives To evaluate the association between lupus severity and cell-bound complement activation products (CB-CAPs) or low complement proteins C3 and C4.Methods All subjects (n=495) fulfilled the American College of Rheumatology (ACR) classification ...
Richard A Furie, Daniel J Wallace, Judith A James, Susan Manzi, Amit Saxena, Rosalind Ramsey-Goldman, Chaim Putterman, John Conklin, Anca Askanase, Jill P Buyon, Elena Massarotti, Roberta Vezza Alexander, Sonali Narain, Cristina Arriens, Kenneth C Kalunian, Christopher E Collins, Ghalib A Bello, Joseph Ahearn   +17 more
doaj   +1 more source

Sequence of the gene for murine complement component C4

Journal of Biological Chemistry, 1989
The gene for murine complement component C4 lies in the S region of the murine major histocompatibility (H-2) complex; in this paper, we report the nucleotide sequence of this gene. The present sequence extends from a SmaI restriction enzyme cleavage site near the 5' end of the gene to a KpnI restriction enzyme cleavage site 569 nucleotides 3' of the ...
R T, Ogata, P A, Rosa, N E, Zepf
openaire   +2 more sources

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

DIAGNOSTIC SIGNIFICANCE OF IMMUNITY MARKERS IN INFLAMMATORY CARDIOMYOPATHY PATIENTS

Российский кардиологический журнал, 2017
Aim. To evaluate diagnostic significance of biomarkers for inflammatory cardiomyopathy (ICM).Material and methods. Totally, 35 patients included with suspected inflammatory cardiomyopathy, chronic heart failure of I-III functional class (FC), decreased ...
S. N. Tereschenko, A. A. Skvortsov, A. Yu. Schedrina, O. Yu. Narusov, K. A. Zykov, A. A. Safiullina, A. V. Sychev, I. V. Zhirov   +7 more
doaj   +1 more source

Serum complements and immunoglobulin profiles in systemic lupus erythematosus patients: An observational study at a teaching hospital

Journal of Family Medicine and Primary Care, 2022
Context: Serum complement proteins and autoantibodies play an important role in the pathogenesis and diagnosis of systemic lupus erythematosus (SLE). Abnormalities in various immunoglobulin levels are described in patients of SLE.
Ranjan Singh Rana, Bitan Naik, Mahima Yadav, Usha Singh, Anup Singh, Shailja Singh   +5 more
doaj   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Rapid activation of the complement system by cuprophane depends on complement component C4 [PDF]

Kidney International, 1998
Hemodialysis with cuprophane dialyzer membranes promotes rapid activation of the complement system, which is thought to be mediated by the alternative pathway. Complete hereditary deficiency of complement C4, a classical pathway component, in two hemodialysis patients provided the opportunity to investigate a possible role of the classical pathway.
Lhotta, Karl, Würzner, Reinhard, Kronenberg, Florian, Oppermann, Martin, König, Paul   +4 more
openaire   +2 more sources

Modeling Dislocation Cutting of γ′ Precipitates in Ni‐Base Superalloys: Linking Atomistic and Dislocation Dynamics Simulations

Advanced Engineering Materials, EarlyView.
Dislocation cutting of γ′ precipitates in Ni‐based superalloys is investigated by linking atomistic simulations with discrete dislocation dynamics. The critical cutting stress is shown to be governed by the antiphase boundary energy, while line tension effects promote edge‐preferred cutting.
Frédéric Houllé, Siwen Gao, Marc Fivel, Anxin Ma, Daria Smirnova, Sriram Anand, Arun Prakash, Julien Guénolé, Alexander Hartmaier, Erik Bitzek   +9 more
wiley   +1 more source

Complement Activation Is Associated With Mortality in Patients With Necrotizing Soft-Tissue Infections—A Prospective Observational Study

Frontiers in Immunology, 2020
Aim: We assessed whether different complement factors and complement activation products were associated with poor outcome in patients with necrotizing soft-tissue infection (NSTI).Methods: We conducted a prospective, observational study in an intensive ...
Markus Korsholm Kristensen, Marco Bo Hansen, Marco Bo Hansen, Martin Bruun Madsen, Cecilie Bo Hansen, Katrine Pilely, Ole Hyldegaard, Ole Hyldegaard, Peter Garred   +8 more
doaj   +1 more source

Spiro‐Phenothiazine Hole‐Transporting Materials: Unlocking Stability and Scalability in Perovskite Solar Cells

Advanced Materials, EarlyView.
Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora, Seung Ju Choi, Jaeki Jeong, Silvia Orecchio, Inés García‐Benito, Manuel Pérez‐Escribano, Joaquín Calbo, Likai Zheng, Minseop Byun, Seyeong Song, Gi‐Hwan Kim, Shaik M. Zakeeruddin, Seog‐Young Yoon, Yimhyun Jo, Agustín Molina‐Ontoria, Enrique Ortí, Nazario Martín, Michael Grätzel   +17 more
wiley   +1 more source