Background: Vitamin D and complement components shared some common pathophysiological pathways in the musculoskeletal system, circulation, and metabolism, which were linked to physical function.
Chi Zhang +8 more
doaj +1 more source
Complement C4 allotypes and psoriasis.
Complement C4 allotypes were studied in a group of 100 patients with psoriasis vulgaria. Frequency of C4A and C4B allotypes in 46 randomly selected unrelated healthy subjects of the same ethnic origin, previously described, was taken as a control pattern.
D Cvorisćec, A Stavljenić, B Vukelić
openaire +4 more sources
Complement C4 - A Genetic Marker in Arthritides [PDF]
KEYWORDS Complement C4; juvenile arthritis; rheumatoid arthritis; osteo arthritis; phenotypes; arthritides ABSTRACT The present study aims at evaluating the role of complement C4 and its specific eletromorphic association with arthritides. C4 typing of the serum samples was carried out by PAGE on 41 juvenile arthritis, 101 rheumatoid arthritis, 25 ...
Ravi Babu, N. Pratibha, A. Padmini
openaire +1 more source
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation [PDF]
Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation.
Agostinis, C +9 more
core +2 more sources
Rapid activation of the complement system by cuprophane depends on complement component C4 [PDF]
Hemodialysis with cuprophane dialyzer membranes promotes rapid activation of the complement system, which is thought to be mediated by the alternative pathway. Complete hereditary deficiency of complement C4, a classical pathway component, in two hemodialysis patients provided the opportunity to investigate a possible role of the classical pathway.
Karl Lhotta +4 more
openaire +3 more sources
Complementing antibody profiles: Assessing antibody function on antigen microarrays [PDF]
Antibody effector functions other than neutralization depend on interactions with soluble and cellular components of the immune system. Antigen recognition is usually oligoclonal, with the different clones of antibodies belonging to different ...
Papp, Krisztián +2 more
core +1 more source
Serological and Genetic Evidence for Altered Complement System Functionality in Systemic Lupus Erythematosus: Findings of the GAPAID Consortium. [PDF]
Systemic lupus erythematosus is a chronic autoimmune disease with multifactorial ethiopathogenesis. The complement system is involved in both the early and late stages of disease development and organ damage.
Czirják, László +6 more
core +1 more source
Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
core +1 more source
Pharmacological management of immune and oxidative disturbances in patients with encephalopathy on the background of hypertension [PDF]
Inclusion of a comprehensive drug treatment of patients with discirculatory encephalopathy cerebrolysin combination with meksidol normalizes the concentration of C3 and C4 components of the complement system, IgG, malondialdehyde, catalase activity ...
Bistrova, N. A. +2 more
core +2 more sources
Renal C3 complement component: feed forward to diabetic kidney disease [PDF]
BACKGROUND: Diabetic nephropathy is the main cause of end-stage renal disease and has reached epidemic proportions. METHODS: Comprehensive genomic profiling (RNAseq) was employed in the ZS (F1 hybrids of Zucker and spontaneously hypertensive heart ...
Dominguez, Jesus H. +3 more
core +1 more source

