Association between copy number variation of complement component C4 and Graves' disease [PDF]
, 2011 Background Gene copy number of complement component C4, which varies among individuals, may determine the intrinsic strength of the classical complement pathway.
Yu-Huei Liu +7 more
core +2 more sources
Complementing antibody profiles: Assessing antibody function on antigen microarrays [PDF]
, 2012 Antibody effector functions other than neutralization depend on interactions with soluble and cellular components of the immune system. Antigen recognition is usually oligoclonal, with the different clones of antibodies belonging to different ...
Papp, Krisztián +2 more
core +1 more source
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation [PDF]
, 2015 Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation.
Agostinis, C +9 more
core +3 more sources
Complement C4 allotypes and psoriasis.
Clinical Chemistry, 1989 Complement C4 allotypes were studied in a group of 100 patients with psoriasis vulgaria. Frequency of C4A and C4B allotypes in 46 randomly selected unrelated healthy subjects of the same ethnic origin, previously described, was taken as a control pattern.
Čvorišćec, Dubravka +2 more
openaire +3 more sources
Serological and Genetic Evidence for Altered Complement System Functionality in Systemic Lupus Erythematosus: Findings of the GAPAID Consortium. [PDF]
, 2016 Systemic lupus erythematosus is a chronic autoimmune disease with multifactorial ethiopathogenesis. The complement system is involved in both the early and late stages of disease development and organ damage.
Czirják, László +6 more
core +1 more source
Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
core +1 more source
Pharmacological management of immune and oxidative disturbances in patients with encephalopathy on the background of hypertension [PDF]
, 2016 Inclusion of a comprehensive drug treatment of patients with discirculatory encephalopathy cerebrolysin combination with meksidol normalizes the concentration of C3 and C4 components of the complement system, IgG, malondialdehyde, catalase activity ...
Bistrova, N. A. +2 more
core +2 more sources
Renal C3 complement component: feed forward to diabetic kidney disease [PDF]
, 2015 BACKGROUND: Diabetic nephropathy is the main cause of end-stage renal disease and has reached epidemic proportions. METHODS: Comprehensive genomic profiling (RNAseq) was employed in the ZS (F1 hybrids of Zucker and spontaneously hypertensive heart ...
Dominguez, Jesus H. +3 more
core +2 more sources
Health Science Reports, 2022 Purpose SARS‐CoV‐2 infection has spread in each corner of the world. Many health systems have dealt with it intensively. The complement system is an instrumental component in the inflammatory immune response and plays a role in the activation of blood ...
Ahmad Bagherimoghaddam +2 more
doaj +1 more source
Frontiers in Endocrinology, 2021 IntroductionGestational Diabetes Mellitus (GDM) development is related to underlying metabolic syndrome that is associated with elevated complement C3 and C4.
Manjunath Ramanjaneya +13 more
doaj +1 more source