Results 31 to 40 of about 68,863 (264)

Serum complements and immunoglobulin profiles in systemic lupus erythematosus patients: An observational study at a teaching hospital

open access: yesJournal of Family Medicine and Primary Care, 2022
Context: Serum complement proteins and autoantibodies play an important role in the pathogenesis and diagnosis of systemic lupus erythematosus (SLE). Abnormalities in various immunoglobulin levels are described in patients of SLE.
Ranjan Singh Rana   +5 more
doaj   +1 more source

Evaluation of complement components C3 and C4 in serum of patient with neoplastic diseases

open access: yesمجلة علوم ذي قار, 2019
The aim of this study is to evaluate the level of complement components C3 and C4 in serum of cancer patients to find which activation pathway of the complment system has the more effect in these cases .
Zeenah weheed Atwan   +2 more
doaj   +4 more sources

Complement Activation Is Associated With Mortality in Patients With Necrotizing Soft-Tissue Infections—A Prospective Observational Study

open access: yesFrontiers in Immunology, 2020
Aim: We assessed whether different complement factors and complement activation products were associated with poor outcome in patients with necrotizing soft-tissue infection (NSTI).Methods: We conducted a prospective, observational study in an intensive ...
Markus Korsholm Kristensen   +8 more
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Serum complement levels in immune thrombocytopenia: Characterization and relation to clinical features

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Background Complement may contribute to platelet destruction in immune thrombocytopenia (ITP), but serum complement levels of ITP patients are not well defined. This study characterized C3, C4, and CH50 levels from 108 ITP patients in comparison with 120
Abraham Z. Cheloff   +2 more
doaj   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

DIAGNOSTIC SIGNIFICANCE OF IMMUNITY MARKERS IN INFLAMMATORY CARDIOMYOPATHY PATIENTS

open access: yesРоссийский кардиологический журнал, 2017
Aim. To evaluate diagnostic significance of biomarkers for inflammatory cardiomyopathy (ICM).Material and methods. Totally, 35 patients included with suspected inflammatory cardiomyopathy, chronic heart failure of I-III functional class (FC), decreased ...
S. N. Tereschenko   +7 more
doaj   +1 more source

Neural Network Adaptive Control With Long Short‐Term Memory

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
ABSTRACT In this study, we propose a novel adaptive control architecture that provides dramatically better transient response performance compared to conventional adaptive control methods. This is accomplished by the synergistic employment of a traditional adaptive neural network (ANN) controller and a long short‐term memory (LSTM) network.
Emirhan Inanc   +4 more
wiley   +1 more source

The Interplay of Cluster and Galaxy Evolution [PDF]

open access: yesAstrophys.SpaceSci.285:157-165,2003, 2003
We review here the interplay of cluster and galaxy evolution. As a case study, we consider the Butcher-Oemler effect and propose that it is the result of the changing rate of cluster merger events in a hierarchical universe. This case study highlights the need for new catalogs of clusters and groups that possess quantified morphologies. We present such
arxiv   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

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