Results 91 to 100 of about 9,987 (203)

Low complement C4B gene copy number predicts short-term mortality after acute myocardial infarction. [PDF]

, 2009
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldBACKGROUND AND OBJECTIVES: Some recent data indicate that risk of death after acute coronary syndrome is under genetic control.
Arason, Gudmundur Johann, Sigurdarson, Sigurdur Thor, Kolka, Ragnhildur, Thorgeirsson, Gudmundur, Blasko, Bernadett, Füst, George, Sasvári-Székely, Mária, Bödvarsson, Sigurdur, Prohászka, Zoltán, Rónai, Zsolt, Kovács, Margit, Sigurdsson, Gardar, Thorbjornsdottir, Perla   +12 more
core   +1 more source

How Escherichia coli Circumvent Complement-Mediated Killing

Frontiers in Immunology, 2017
Complement is a crucial arm of the innate immune response against invading bacterial pathogens, and one of its main functions is to recognize and destroy target cells.
Angela S. Barbosa, Afonso G. Abreu, Afonso G. Abreu   +2 more
doaj   +1 more source

Serum complement C4b, fibronectin, and prolidase are associated with the pathological changes of pulmonary tuberculosis. [PDF]

BMC Infect Dis, 2014
AbstractBackgroundMycobacterium tuberculosisinfection can activate the immune system, leading to characteristic pathological changes such as inflammatory granuloma, caseous necrosis, and cavity formation.MethodsClinical data of 187 cases of pulmonary tuberculosis (PTB) were analyzed using statistical methods, while serum levels of complement C4b (C4b),
Wang C, Li YY, Li X, Wei LL, Yang XY, Xu DD, Jiang TT, Li ZJ, Chen ZL, Zhang X, Liu JY, Ping ZP, Li JC.   +12 more
europepmc   +4 more sources

Chandipura Virus: An Emerging Neurological Threat Transmitted by Sandflies in India

Immunity, Inflammation and Disease, Volume 14, Issue 7, July 2026.
Chandipura virus (CHPV), a neurotropic arbovirus transmitted primarily by sandflies, has emerged as a significant public health concern in India following recurrent outbreaks with high pediatric fatality rates. This review highlights the virus's virology, transmission dynamics, clinical features, and the urgent need for improved diagnostics ...
Abrar Ahmad Zargar, Reena Gupta, P. Krishnamoorthy   +2 more
wiley   +1 more source

An age-associated decrease in the frequency of C4B*Q0 indicates that null alleles of complement may affect health or survival [PDF]

, 2007
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldWe studied the distribution of complement C4, C3, and factor B allotypes in 423 healthy Icelandic subjects from 17 to 89 years of age.
Arason, Gudmundur Johann, Sigurdarson, Sigurdur Thor, Füst, Georg, Gudmundsson, Sveinn, Thorgeirsson, Gudmundur, Kramer, Judit, Bodvarsson, Sigurdur, Sigurdsson, Gardar   +7 more
core   +1 more source

Identification of SNPs Associated With mRNA Expression Differences of the Complement Receptor Type 1‐Like Gene in Landrace Weaned Piglets

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
ABSTRACT Objective The aim of this study is to investigate the association between single nucleotide polymorphisms (SNPs) of porcine complement receptor 1‐like (CR1‐like) gene and its mRNA expression. Methods SNP identification, qRT‐PCR absolute quantification, linkage disequilibrium analysis and dual‐luciferase reporter assay were performed using 392 ...
Wei Yin, Jiachen Cheng, Qiongyu Li, Luyang Xu, Hongquan Li, Kuohai Fan, Zhenbiao Zhang, Na Sun, Panpan Sun, Huizhen Yang   +9 more
wiley   +1 more source

Independent association of serum amyloid P component, protein S, and complement C4b with complement C4b-binding protein and subsequent association of the complex with membranes.

Journal of Biological Chemistry, 1990
C4b-binding protein (C4BP) is a large complex assembly of eight subunits that functions as an inhibitor of the complement cascade. A portion of the C4BP in serum exists as a complex with protein S. This study demonstrated that another protein, serum amyloid P component (SAP), also formed a calcium-dependent complex with C4BP.
R A, Schwalbe, B, Dahlbäck, G L, Nelsestuen   +2 more
openaire   +2 more sources

LigB binds complement proteins C3b and C4b. [PDF]

, 2012
Recombinant Lig proteins were tested for interaction with human C3b (A) and C4b (B) in an ELISA described in Materials and Methods. The means and standard deviations or ranges (uncapped error bars) from multiple independent determinations (indicated in ...
Henry A. Choy (36168)
core   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, Volume 9, Issue 6, Page 1142-1166, June 2026.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Early and extensive CD55 loss from red blood cells supports a causal role in malarial anaemia. [PDF]

, 2011
BACKGROUND\ud \ud Levels of complement regulatory proteins (CrP) on the surface of red blood cells (RBC) decrease during severe malarial anaemia and as part of cell ageing process.
Fried, Michal, Moses Gwamaka, Michal Fried, Duffy, Patrick E, Patrick E Duffy, Gwamaka, Moses, Gonzalo Domingo, Domingo, Gonzalo   +7 more
core   +1 more source