Results 51 to 60 of about 697,969 (251)
Function of the activated fourth component of complement (C4b) in activation of C2 [PDF]
FEBS Letters, 1982 In course of pathway activation fourth component complement is by acCT into (8800 M,) C4b (197 M,). It well known C4b forms reversible complex the second of compleC2, with essential participation Mg2+ [ 1,2]. Furthermore, C4b serves as an acceptor for CZ, activated by cleavage by Ci; the complex formed, C4b2a,b is independent of Mg2+ and has ...
G. Schmidt +3 more
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Investigation of complement component C4 copy number variation in human longevity. [PDF]
PLoS ONE, 2014 Genetic factors have been estimated to account for about 25% of the variation in an adult's life span. The complement component C4 with the isotypes C4A and C4B is an effector protein of the immune system, and differences in the overall C4 copy number or
Friederike Flachsbart +6 more
doaj +1 more source
Intensive Care Medicine Experimental, 2020 Background Mechanical ventilation can induce or even worsen lung injury, at least in part via overdistension caused by too large volumes or too high pressures.
Friso M. de Beer +11 more
doaj +1 more source
Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components. [PDF]
PLoS ONE, 2013 Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Jasmin Schwab +7 more
doaj +1 more source
Commensurability classes of 2-bridge knot complements [PDF]
Algebr. Geom. Topol. 8 (2008) 1031-1057, 2006 We show that a hyperbolic 2-bridge knot complement is the unique knot complement in its commensurability class. We also discuss constructions of commensurable hyperbolic knot complements and put forth a conjecture on the number of hyperbolic knot complements in a commensurability class.
arxiv +1 more source
Structural and functional studies of complement inhibitor C4b-binding protein [PDF]
Biochemical Society Transactions, 2002 C4b-binding protein (C4BP) is a potent inhibitor of the classical pathway of the complement system. This large plasma glycoprotein consists of seven identical α-chains and a unique β-chain held together by disulphide bridges. Both types of subunits are composed almost exclusively of complement control protein domains (CCPs).
openaire +4 more sources
Nature Communications, 2023 IgG3 is unique among the IgG subclasses due to its extended hinge, allotypic diversity and enhanced effector functions, including highly efficient pathogen neutralisation and complement activation.
Leoni Abendstein +6 more
semanticscholar +1 more source
Symmetries and hidden symmetries of $(ε, d_L)$-twisted knot complements [PDF]
Algebr. Geom. Topol. 22 (2022) 601-656, 2019 In this paper we analyze symmetries, hidden symmetries, and commensurability classes of $(\epsilon, d_L)$-twisted knot complements, which are the complements of knots that have a sufficiently large number of twists in each of their twist regions. These knot complements can be constructed via long Dehn fillings on fully augmented links complements.
arxiv +1 more source
bioRxiv, 2022 Neisseria gonorrhoeae (Gc) is a human-specific pathogen that causes the sexually transmitted infection gonorrhea. Gc survives in neutrophil-rich gonorrheal secretions, and recovered bacteria predominantly express phase-variable, surface-expressed opacity-
Lacie M. Werner +8 more
semanticscholar +1 more source
Freeze-dried plasma proteins are stable at room temperature for at least 1 year
Clinical Proteomics, 2017 Thirty human EDTA plasma samples from male and female subjects ranging in age from 24 to 74 years were collected on ice, processed ice cold and stored frozen at −80 °C, in liquid nitrogen (LN2), or freeze dried and stored at room temperature in a ...
Jaimie Dufresne +5 more
doaj +1 more source