Results 51 to 60 of about 424,323 (243)

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model

Biomedicines, 2022
Introduction: immune-mediated necrotising myopathy (IMNM) is associated with pathogenic anti-signal recognition particle (SRP) or 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies, at least partly through activation of the classical pathway of ...
Sarah Julien, Douangsone Vadysirisack, Camil Sayegh, Sharan Ragunathan, Yalan Tang, Emma Briand, Marion Carrette, Laetitia Jean, Rachid Zoubairi, Henri Gondé, Olivier Benveniste, Yves Allenbach, Laurent Drouot, Olivier Boyer   +13 more
doaj   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source

Complement factor C5 in Atlantic salmon (Salmo salar): characterization of cDNA, protein and glycosylation [PDF]

, 2019
Complement component 5 (C5) is an essential factor of the defensive complement system in all vertebrates. We report the characterization of C5 cDNA and protein from Atlantic salmon (Salmo salar), a teleost fish species of high importance in aquaculture ...
Johansen, Wenche, Moen, Anders, Agusti-Ridaura, Celia, Grove, Søren, Anonsen, Jan Haug, Strætkvern, Knut Olav, Azar, Amir Sefidmouy   +6 more
core   +1 more source

Defect‐Engineered Microwave‐Responsive Ni@C Composites From Waste PET for Catalytic Plastic Upcycling

Advanced Materials, EarlyView.
A circular upcycling strategy transforms waste poly(ethylene terephthalate) bottles into microwave‐responsive Ni@C catalyst featuring lattice‐distorted nickel cores and defective carbon shells. These strain‐rich heterointerfaces enhance dielectric loss and promote localized microwave hotspots, accelerating peroxymonosulfate activation and polymer‐chain
Xiao Lu, Shiying Ren, Jingkai Lin, Kunsheng Hu, Yalan Mo, Shaobin Wang, Wenjie Tian, Xiaoguang Duan   +7 more
wiley   +1 more source

A novel role of complement: mice deficient in the fifth componenet of complement (C5) exhibit impaired liver regeneration. [PDF]

, 2001
Components of innate immunity have recently been implicated in the regulation of developmental processes. Most strikingly,complement factors appear to be involved in limb regeneration in certain urodele species.
MASTELLOS, D, LAMBRIS, J. D., PAPADIMITRIOU, J. C, TSONIS, P. A, FRANCHINI, Silvia   +4 more
core   +1 more source

Safety and efficacy of pegcetacoplan in paroxysmal nocturnal hemoglobinuria

Therapeutic Advances in Hematology, 2022
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, hematologic disease characterized by complement-mediated hemolysis, thrombosis, and various degrees of bone marrow dysfunction.
Raymond S.M. Wong
doaj   +1 more source

Human Neutrophils Respond to Complement Activation and Inhibition in Microfluidic Devices

Frontiers in Immunology, 2021
Complement activation is key to anti-microbial defenses by directly acting on microbes and indirectly by triggering cellular immune responses. Complement activation may also contribute to the pathogenesis of numerous inflammatory and immunological ...
Sinan Muldur, Sinan Muldur, Douangsone D. Vadysirisack, Sharan Ragunathan, Yalan Tang, Alonso Ricardo, Camil Elie Sayegh, Daniel Irimia, Daniel Irimia   +8 more
doaj   +1 more source

Multi‐Biomimetic Structural Colors Inspired by Pearls and Bird Feathers

Advanced Materials, EarlyView.
A dual‐biomimetic strategy mimicking pearls and bird feathers is proposed to construct full‐gamut structural colors. By integrating a non‐strictly periodic inorganic multilayer architecture with tunable light absorbers, this facile approach circumvents the complex fabrication of traditional 1D photonic crystals, offering immense potential for cosmetics,
Zhiwei Wang, Qiuyu Cheng, Qiuyu Jin, Fu Tang, Wenbin Cao, Ayahisa Okawa, Takuya Hasegawa, Takehiro Goto, Natsumi Yamaguchi, Takumi Tanaka, Te‐Wei Chiu, Tohru Sekino, Shu Yin   +12 more
wiley   +1 more source