Veterinary Sciences, 2016 Evading innate immunity is a prerequisite for pathogenic microorganisms in order to survive in their respective hosts. Concerning Lyme disease spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato group, a broad range of diverse vertebrates ...
Peter Kraiczy
doaj +1 more source
Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1beta Release by Pulmonary Epithelial Cells [PDF]
, 2018 Phosphocholine-modified bacterial cell wall components are virulence factors enabling immune evasion and permanent colonization of the mammalian host, by mechanisms that are poorly understood.
Grau, Veronika +11 more
core +1 more source
Staphylococcus pseudintermedius Sbi paralogs inhibit complement and bind IgM, IgG Fc and Fab.
PLoS ONE, 2019 The success of staphylococci as pathogens has been attributed, in part, to their ability to evade their hosts' immune systems. Although the proteins involved in evasion have been extensively studied in staphylococci affecting humans little ...
Alaa H Sewid +4 more
doaj +1 more source
Sequence variations and protein expression levels of the two immune evasion proteins Gpm1 and Pra1 influence virulence of clinical Candida albicans isolates. [PDF]
PLoS ONE, 2015 Candida albicans, the important human fungal pathogen uses multiple evasion strategies to control, modulate and inhibit host complement and innate immune attack. Clinical C.
Shanshan Luo +4 more
doaj +1 more source
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
, 2017 Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
PLoS PathogensBorreliella burgdorferi, the causative agent of Lyme disease, has evolved unique complement evasion proteins that promote its ability to establish and maintain infection in mammalian hosts. Among these is B.
Alexandra D Powell-Pierce +6 more
doaj +1 more source
Characteristics of Staphylococcus aureus infections to consider in designing an effective vaccine. [PDF]
, 2010 _Staphylococcus aureus_ is a very versatile and adaptable microorganism. It can potentially infect virtually any host tissue. Given the appropriate conditions it can become a life-threatening pathogen, or a commensal colonizer of the nose.
Beatriz E. Baca +2 more
core +1 more source
Hepatitis C virus infection upregulates CD55 expression on the hepatocyte surface and promotes association with virus particles [PDF]
, 2013 CD55 limits excessive complement activation on the host cell surface by accelerating the decay of C3 convertases. In this study, we observed that hepatitis C virus (HCV) infection of hepatocytes or HCV core protein expression in transfected hepatocytes ...
A. M. Di Bisceglie +54 more
core +2 more sources
eLife, 2014 Genome-wide association studies have found variation within the complement factor H gene family links to host susceptibility to meningococcal disease caused by infection with Neisseria meningitidis (Davila et al., 2010).
Joseph JE Caesar +10 more
doaj +1 more source
Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies [PDF]
, 2006 Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA ...
Ahmed Raza +37 more
core +1 more source