Results 241 to 250 of about 392,488 (288)

Bioorthogonal tuning of nanosurface opsonisation <i>via</i> click coupling of a complement fusion protein inhibitor.

Chem Commun (Camb)
Jacques S, Gaikwad H, Pillatzke J, Moghimi SM, Simberg D.   +4 more
europepmc   +1 more source

Measurement of complement proteins may aid interpretation of pathophysiology in kidney transplant recipients with atypical hemolytic uremic syndrome. [PDF]

CEN Case Rep
Miura M, Higashiyama H, Tsuji T, Ohtani K, Wakamiya N.   +4 more
europepmc   +1 more source

Complement factor H supplementation rather than complete C3 knockout provides therapeutic benefits in IgA nephropathy. [PDF]

Mol Biomed
Li X, Ni X, Yuan X, Wu H, Shi S, Liu L, Lv J, Zhang H, Zhu L.   +8 more
europepmc   +1 more source

Complement Dysregulation in Kidney Diseases: Mechanisms, Biomarkers, and Emerging Targeted Therapies. [PDF]

Int J Mol Sci
Jesiołowski P, Krzywda M, Furmańczyk-Zawiska A, Durlik M.   +3 more
europepmc   +1 more source

New Anticomplement Drugs in Nephrology: Mechanism and Indication.

Kidney Blood Press Res
Macciò L, Russo E, Costigliolo F, Battaglia Y, Viazzi F, Esposito P.   +5 more
europepmc   +1 more source

Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections [PDF]

Blood, 2006
The complement system is an essential element in our innate defense against infections with Neisseria meningitidis. We describe 2 cases of meningococcal septic shock, 1 of them fatal, in 2 children of a Turkish family. In the surviving patient, alternative pathway activation was absent and factor D plasma concentrations were undetectable ...
Sprong, T., Roos, D., Weemaes, C.M.R., Neeleman, C., Geesing, C.L., Mollnes, T.E., Deuren, M. van   +6 more
openaire   +4 more sources

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Isolation of a carp complement protein homologous to mammalian factor D

Molecular Immunology, 1994
Factor D of carp (Cyprinus carpio) complement was purified to apparent homogeneity by a 4-step chromatographic procedure and examined for physicochemical and functional properties. Carp factor D proved to be an alpha-globulin with a molecular mass of 29 kDa and the serum concentration was estimated to be 6 micrograms/ml.
T, Yano, M, Nakao
openaire   +2 more sources

Specific interactions of polystyrene biomaterials with factor D of human complement

Biomaterials, 1993
The contact of blood with some biomaterials results in complement activation, primarily by the alternative pathway (AP). Insoluble polystyrene derivatives bearing isolated sulphonate groups (PSSO3) deplete complement, whereas identical surfaces substituted with both sulphonate and hydroxymethyl groups (PSCH2OH-SO3) are non-activators.
Pascual M, Plastre O, Montdargent B, Labarre D, Schifferli JA   +4 more
openaire   +3 more sources

Factor D of the alternative pathway of bovine complement: Isolation and characterization

Veterinary Immunology and Immunopathology, 1984
Factor D of the bovine alternative complement pathway has been purified by chromatography on CM-Sephadex C-50, Sephacryl S-200 and hydroxylapatite. The isolated factor D (0.25 mg from 1 litre of bovine serum) had an apparent molecular weight of 27,500 and a pI of 7.2. In whole bovine serum the pI of factor D was also 7.2.
M, Menger, W P, Aston
openaire   +2 more sources